Synthesis and Structure of the Nanomolecular Multicyclophane "Kuratowskiphane," an Achiral Non-Planar (K3,3) Topological Stereoisomer

Chao-Tsen Chen, Peter Gantzel, and Jay S. Siegel, K. K. Baldridge, Robin B. English, and D. M. Ho

Contribution from the University of California, San Diego, the San Diego Supercomputer Center, Rhodes University, S. Africa, and Princeton University

Angew. Chem. Int. Ed. Engl. 1995 fall cover issue.

Synopsis

The directed synthesis of specific topological stereoisomers is at the forefront of stereocontrolled synthesis of nanomolecules. with increasing size and weight dimensions, specific spacial entwinement becomes a significant design and synthesis concern. this investigation elucidates the K3,3 topological stereoelement through the design, directed synthesis, and complete molecular characterization of a nanomoelcular multicyclophane.