Table of Contents

• The Primary Source of Macromolecular Structure Data  - The Protein Data Bank (PDB)
• Brief History
• Holdings
• Curation
• Growth with Reference to Structure Genomics
• Obsolete Entries
• Entries on Hold

Format

• Effective Use of the PDB

• Id Searches
• SearchLite - Keyword Searches
• SearchFields - Specific Queries
• Iterative Queries

• Derived Resources - General
• Access - via Molecular Information Agent (MIA)
• Structure - Details and Quality - PDBSum
• Structure Classification - SCOP and CATH
• Structure Comparison - The General Problem
• Structure Comparison Methods - CE, DALI, and VAST
• Other
• Class Problems
• How do I obtain a list of all human DNA structures in the PDB that are not in complex with another molecule?
• Finding sequence vs structure homology in the A and B Chains of Hemoglobin
• Exploring poor geometry - Neurotoxin b
• Finding cyclic peptides
• How similar are the structures of ribonuclease A in different crystal forms?

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