Post Doctoral, Protein Crystallography
Massachusetts General Hospital-Harvard Medical School Affiliate
Department: MedicineLocation: Boston, MA
Start Date: June 1, 2010
Duration: 3 years
Description: We are seeking a talented and highly motivated Postdoctoral Fellow to work within the Structural Biology Group on the structure and function of eukaryotic membrane proteins associated with human disease. A PhD degree in structural biology, molecular biology, chemistry or a related field and at least three years of post-doctoral experience in protein crystallography are required. Applicants with experience in cloning and expression of recombinant protein in bacterial, yeast or insect cell systems, large-scale protein purification, macromolecular crystallization and structure determination are preferred. Salary commensurate with experience.
Please submit: Cover letter, CV with list of publications, and 3 references
Person to contact: Gregory Hamann
Email address: GHAMANN@PARTNERS.ORG
Phone number: 617-724-8839
Fax number: 617-726-7491
Job Posted: 02/03/10
Job ID Number: 1265206252
Postdoctoral research associate
Jackson State University
Department: ChemistryLocation: Jackson
Start Date: June 01, 2010
Description: Applications are accepted to fill a postdoctoral research associate position with the starting date of June 01, 2010 to work in the laboratory of Dr. Alamgir Hossain at Jackson State University. This project involves the studies on molecular recognition of anions with environmental and biological importance. The candidate is expected to work in a diverse environment, conduct research in a highly interdisciplinary area and write research manuscripts for peer review journals, The applicant should have a PhD degree in chemistry within three years. Background in host-guest chemistry, synthetic organic chemistry or inorganic supramolecular chemistry are preferred. Research experiences in NMR, potentiometric studies, UV-VIS, fluorescence and Raman spectroscopies are highly desirable. This is a full time position, therefore the successful candidate must work a minimum of 40 hours per week. This position will require a very highly motivated researcher with strong commitments. Applications should consist of a curriculum vitae, brief summary of research experience, and the names and email addresses of three referees. Please send applications by email to alamgir@chem.jsums.edu. The position is available for one year and can be extended upon satisfactory progress of the work. For further information please contact: Md. Alamgir Hossain Assistant Professor Department of Chemistry Jackson State University 1325 Lynch Street, Jackson, MS 39217 Tel: 601-979-3748 Fax: 601-979-3674 Email: alamgir@chem.jsums.edu http://chem.jsums.edu/alamgir
Person to contact: Md. Alamgir Hossain
Surface mail address: Department of Chemistry, Jackson, MS 39217
Email address: alamgir@chem.jsums.edu
Phone number: 601-979-3748
Fax number: 601-979-3674
Job Posted: 02/01/10
Job ID Number: 1265079560
Postdoctoral Research Associate
University of Wisconsin-Milwaukee
Department: Physics DepartmentLocation: Milwaukee, Wisconsin
URL: www4.uwm.edu/letsci/physics/
Start Date: 1 March 2010 (flexible)
Duration: 1-1.5 years (renewable)
Description: We are seeking to fill two DOE-funded positions in the area of x-ray scattering. The areas of work include those which exploit the novel capabilities of modern x-ray sources, such as synchrotrons and the x-ray free electron laser. One focus is on novel diffraction theories for structure determination of non-crystallized single biomolecules or ensembles of randomly oriented ones. Another is on surface x-ray diffraction, and possibly on the structure of liquid crystals. Opportunities exist for suitably qualified candidates for either experimental or theoretical work. One position is available for a year and a half in the first instance and the other for a year. Both positions may be renewed for longer periods. A competitive salary and benefits package will be offered. A Ph.D. in physics or a related area is required. Please contact Prof. Paul Lyman (plyman@uwm.edu) or Prof. Dilano Saldin (dksaldin@uwm.edu). Information about the Department and ongoing research is available at http://www4.uwm.edu/letsci/physics/.
Please submit: CV, names of 3 referees
Person to contact: Prof. P. F. Lyman or Prof. D. K. Saldin
Surface mail address: Department of Physics, University of Wisconsin-Milwaukee
Email address: plyman@uwm.edu or dksaldin@uwm.edu
Phone number: +1-414-229-4626 or +1-414-229-6423
Fax number: +1-414-229-5589
Job Posted: 12/17/09
Job ID Number: 1261092423
Postdoctoral Associate: Physics Problems in Protein Structure Determination
Cornell University
Department: PhysicsLocation: Ithaca, NY USA
Start Date: 3/1/10
Duration: 2 years (contingent on sustained funding)
Description: Our group studies a variety of problems related to the determination of protein structures by X-ray crystallography. One area of current focus is the physics of cryopreservation of protein solutions, protein crystals and other biological materials. We want to understand what happens to water and protein when they are cooled in solution, inside crystals and inside cells; and how factors including cryoprotectants and cooling rates affect ice nucleation and growth and protein conformational transformations. Based on this understanding, we want to develop new methods to maximize the information that can be obtained from protein crystals using X-ray crystallography, to apply these methods to select proteins, and to improve the cryopreservation of cells and tissues. We have recently developed two methods that have significant potential to impact our understanding of protein structure and dynamics. The first allows us to cool crystals 100 times faster than in conventional flash cooling methods. Most crystals can now be successfully cooled without any penetrating cryoprotectants, and the resulting X-ray determined protein structures are closer to the biologically relevant room-temperature structure. The second method allows us to collect high quality data from many proteins as a continuous function of temperature between 300 K and 100 K, including in the heretofore inaccessible region between 220 K and 180 K, near the protein dynamical transition. This makes possible a variety of studies of the conformational energy landscape and protein-solvent interactions. We are seeking a postdoctoral associate to continue and extend our current program, which includes a variety of physical measurements in addition to synchrotron-based X-ray crystallography. Candidates should have excellent "hands-on" experimental skills, interests in physics, physical chemistry and protein structure/function, and some synchrotron-based X-ray diffraction experience. They should be able to work quickly and efficiently, with a keen eye for what is important, and have excellent oral and written communication skills in English. Because of difficulties in evaluating credentials, interviewing, and securing visas for foreign candidates, only applications from those currently resident in and having visa status within the US or Canada will be considered.
Please submit: CV, brief (2 paragraph) statement of interest.
Person to contact: Robert E Thorne
Email address: ret6@cornell.edu
Job Posted: 12/17/09
Job ID Number: 1261089874
BCMP in collaboration with Central Arizona Medical Center - Florence, AZ
Location: CENTRAL ARIZONA MEDICAL CENTERStart Date: immediately
Description: Florence Community Healthcare, a 65-bed full-service community hospital located at 450 West Adamsville Road in Florence Arizona, will open it’s doors to the public late Fall of 2009. Renovation of the former Pinal General Hospital is underway and on target to meet the late Fall Grand Opening deadline. Florence Community Healthcare will be a world-class hospital, close to home. It will feature state-of-the-art technology as well as superior patient care. “One of our top priorities is to provide patients with an exceptional experience, in a caring and safe environment,” said Edward McEachern, MD and CEO of parent company, Initiatives Healthcare, Inc. “We also recognize the central role healthcare plays in a community and look forward to being a strong partner in creating a healthier community. We will be participating in a variety of community activities from now until our opening, and welcome the opportunity to present to local organizations.” At the time of completion in late Fall, it is anticipated that over 200 permanent positions will be created. “This will enhance the local and regional economy as well as provide a variety of employment opportunities. We are offering excellent career opportunities for healthcare professionals as well as other positions in the service industry sector,” McEachern said. “We are looking for people who want to make a difference in the community and seek candidates who want to be part of the Florence Community Healthcare team!” Please contact Andreas Kreusch call 602-677-4677or email applications to myflorencecareers@florencecommunityhealthcare.com. Florence Community Healthcare Facility is latest addition to Florence Arizona
Please submit: CV, 3 references, date of availability
Person to contact: F Sliz
Surface mail address: 450 ADAMSVILLE ROAD, PO BOX 2080
Email address: akresch@gfn.org
Job Posted: 12/07/09
Job ID Number: 1260183139
Postdoctoral Research Associate
Purdue University
Department: Biological SciencesLocation: West Lafayette, IN, USA
Start Date: Immediate
Duration: 1 year; extension possible
Description: Postdoctoral Position in Structural Biology of Membrane Proteins. A postdoctoral is sought to work on structure-function of one or more integral membrane proteins or protein complexes in a multi-investigator multi-institutional project centered in the structural biology group of the Dept. of Biological Sciences, Purdue University. The major expertise(s) that the person should bring to the projects include x-ray crystallography and/or structure analysis by single particle cryo-electron microscopy. Experience in membrane protein purification is relevant. The five laboratories at Purdue involved in this project will move to a new building at the end of this year. Interested parties should respond, including a CV and the names/addresses of 3 references, to W. A. Cramer (waclab@purdue.edu) by November 23, 2009.
Please submit: CV; 3 letters of reference
Person to contact: W. A. Cramer
Surface mail address: 915 West State St., Lilly Hall, W. Lafayette, IN 47907
Email address: waclab@purdue.edu
Phone number: 765-494-4956
Fax number: 765-496-1189
Job Posted: 11/03/09
Job ID Number: 1257276311
Postdoctoral Fellow
Cold Spring Harbor Laboratory
Location: New YorkDescription: Applications are invited for postdoctoral positions at Cold Spring Harbor Laboratory (CSHL) from highly enthusiastic individuals with strong interest in utilizing structural, electrophysiological, and biochemical approaches to study fundamental problems in ion and substrate transports across the membrane. Our goal is to understand molecular basis for synaptic transmission and neurological disorders and diseases. We use x-ray crystallography to obtain atomic structures of target membrane/glyco proteins and test structure-based functional hypotheses by various techniques including electrophysiology, analytical centrifugation, and fluorescence assay. We are equipped with a state-of-the-art facility to conduct membrane/glyco protein crystallography and functional studies including a high-throughput protein screening system, an automated crystallization screening device, a recently updated home x-ray source, electrophysiology rigs, and other setups such as isothermal titration colorimetry device. CSHL is also located within 30 min driving distance from the National Synchrotron Light Source at Brookhaven National Laboratory. Most importantly, a highly collaborative environment at CSHL provides a unique opportunity for postdocs to interact with scientists from various fields including cancer biology, neuroscience, and plant biology. Candidates must hold (or soon expect to hold) PhD in biochemistry, molecular biology, biophysics or related fields. Strong background in molecular biology, biochemistry, large-scale protein expression in eukaryotic and prokaryotic cells, and purification of membrane/glyco proteins is desired. Experience in x-ray crystallography or electrophysiology is desirable but not necessary. For more information, please check the laboratory website (http://www.cshl.edu/public/SCIENCE/furukawa.html) or contact me via email. Please send CV, a summary of research experience and interest, and three references to Hiro Furukawa by email at furukawa@cshl.edu
Please submit: CV, Brief description of research interest, 3 references
Person to contact: Hiro Furukawa
Surface mail address: 1 Bungtown Rd., Cold Spring Harbor, NY 11724
Email address: furukawa@cshl.edu
Phone number: 516-367-8872
Fax number: 516-367-8873
Job Posted: 10/27/09
Job ID Number: 1256670416
Postdoctoral Associate
Cornell University
Department: MacCHESSLocation: Ithaca, NY
URL: search-lepp@cornell.edu
Description: Post-doctoral Associate - Biological Small-Angle Solution Scattering Cornell High-Energy Synchrotron Source The Macromolecular Diffraction Facility of the Cornell High-Energy Synchrotron Source (MacCHESS) has an opening for a post-doctoral associate. Applicants should have a Ph.D. degree in a field relevant to structural biology. Preference will be given to those with experience in x-ray solution scattering on biological systems (SAXS and WAXS). The successful candidate will be expected to collaborate with visiting research groups collecting data at MacCHESS. Activities will include applying state-of-the art algorithms to BioSAXS data, modeling macromolecular complexes, or studying conformationally- variable regions of proteins. Experience in developing hardware and software for automation including microfluidics is also desirable. Located on an ivy-league university campus in picturesque upstate New York, the Cornell High-Energy Synchrotron Source (CHESS) serves a world-wide user base of structural biologists, chemists, physicists, and engineers. MacCHESS is an NIH-supported National Resource providing support for structural biology at CHESS. MacCHESS is a heavily team-oriented environment. Good clear communication skills are a must, including fluency in the English language. This position is a 1-year appointment, renewable for up to 3 years total, contingent upon availability of funds and employee performance. Please provide an application and arrange to have at least three letters of reference sent to: Dr. Marian Szebenyi, Chair Postdoctoral Associate Search Committee Newman Lab Cornell University Ithaca, NY 14853 USA Applications should include a cover letter, curriculum vita, a publication list, and a detailed summary of research experience and interests. Electronic submissions and inquiries may be addressed to search-lepp@cornell.edu. Deadline for application is November 15, 2009. Starting date is negotiable. Cornell is an equal opportunity employer.
Phone number: 607-255-4952
Fax number: 607-254-4552
Job Posted: 10/19/09
Job ID Number: 1255960967
NIH Funded Post-Doctoral Fellow in RNA Structure & Function
The University of Rochester Medical Center
Department: Department of Biochemistry & BiophysicsLocation: Rochester, New York
URL: dbb.urmc.rochester.edu/labs/wedekind/Site/Wedekind_Home.html
Start Date: immediately
Duration: 1-2 year or more
Description: The University of Rochester Medical Center Department of Biochemistry & Biophysics Rochester, New York, USA An NIH funded post-doctoral position is available immediately to investigate the mechanisms of action of riboswitches and ribozymes. Primary experimental methods include X-ray crystallography, computation refinement, single-turnover kinetics, small angle X-ray scattering (SAXS), synthetic organic chemistry, protein purification, dynamic light scattering, and molecular biology. Qualified candidates must hold a Ph.D. in chemistry, biochemistry or a related field. Prior experience with X-ray crystallography is preferred. Post-doctoral fellows will have an opportunity to work with other trainees and staff members in a modern research lab with excellent equipment and resources. Travel opportunities are also available for data collection and to present scientific findings at meetings. For additional information please send a curriculum vitae and the names of three references to Prof. Joseph Wedekind (joseph.wedekind@rochester.edu).
Please submit: cv, names of three references
Person to contact: Joseph Wedekind
Surface mail address: 601 Elmwood Avenue, Box 712, Dept. Biochemistry & Biophysics
Email address: joseph.wedekind@rochester.edu
Phone number: (585) 273-4516
Fax number: (585) 275-6007
Job Posted: 10/15/09
Job ID Number: 1255634724
Post-Doctoral Fellow
St. Jude Children's Research Hospital
Department: Structural BiologyLocation: Memphis, TN
Start Date: immediately
Description: A post-doctoral position in Structural Biology at St. Jude Children’s Research Hospital is available for highly motivated applicants to study the structure and function of replication proteins and their interaction with DNA. This position is available for applicants with a strong interest in protein crystallography and structural biology. Applicants should have recent PhD experience in biochemistry, molecular biology, crystallography, or a related field. The Structural Biology Department at St. Jude is highly interactive and has state-of-the-art facilities for structural studies, including shared synchrotron time. To apply, please send a cover letter, CV with list of publications, and 3 references.
Please submit: cover letter, CV with list of publications, and 3 references
Person to contact: Eric Enemark
Surface mail address: Department of Structural Biology, St. Jude Children’s Research Hospital, Mail Stop 311, 262 Danny Thomas Place, Memphis, TN 38105
Email address: Eric.Enemark@stjude.org
Job Posted: 09/28/09
Job ID Number: 1254154966
Postdoc position in structural biology & biochemistry
UC San Diego
Department: School of PharmacyLocation: La Jolla
Start Date: Jan 2010
Description: Postdoc Job Description: A full-time postdoctoral position is available at UC San Diego. We are looking for a highly motivated postdoctoral research fellow to join our laboratory. We are interested in structure-function studies of protein complexes involved in DNA repair process using a combination of x-ray crystallography, biochemical, and biophysical techniques. Qualifications: Successful candidates should have received a Ph.D. degree in structural biology, biophysics, biochemistry, chemistry, or related discipline. Applicants with experience in cloning and expression of recombinant protein in bacterial, yeast or insect cell systems, large-scale protein purification, macromolecular crystallization and structure determination are preferred. Applicants with a strong background in protein and nucleic acids biochemistry are also encouraged to apply. Good written and oral communication skills are essential. Procedure to Apply: Please send your CV, including contact information of 3 references (address, phone, and email) and list of your experimental expertise to Dong Wang, PhD. dongwang@stanford.edu.
Please submit: CV, including contact information of 3 references (address, phone, and email) and list of your experimental expertise
Person to contact: Dong Wang, PhD.
Email address: dongwang@stanford.edu
Job Posted: 09/23/09
Job ID Number: 1253754175
Research Associate
Stanford Synchrotron Radiation Lightsource
Location: SLAC National Accelerator LabURL: www-ssrl.slac.stanford.edu/
Start Date: ASAP
Description: The Stanford Synchrotron Radiation Lightsource (SSRL) has an opening for a Research Associate to help support our materials sciences small angle X-ray scattering program. This position has a component (roughly 50%) that involves beam line development at SSRL and a part (remaining 50%) involving SAXS related materials science. The facility part will involve instrument development at the SSRL materials sciences SAXS beam line (1-4). This will involve rebuilding much of the in-hutch beam line components (e.g., slits, flight paths, sample stages, etc.). There will also be some development of sample environments such as furnaces and an in-vacuum, grazing incidence capability. The science part of this position is somewhat flexible but will involve studies of complex materials using SAXS and related techniques (e.g., diffraction). It is likely that some of this will include collaborative studies with investigators at universities and national labs. Qualifications: a Ph.D. in a physical science. Experience with synchrotron small angle X-ray and/or neutron scattering. Good interpersonal skills. Some experience with instrumentation design and development and computer-instrument interfacing is desirable.
Please submit: CV
Person to contact: Mike Toney
Email address: mftoney@slac.stanford.edu.
Job Posted: 09/23/09
Job ID Number: 1253733688
Postdoctoral fellow
University of Minnesota
Department: Biochemistry, Molecular Biology, and BiophysicsLocation: Minneapolis, MN
URL: www.cbs.umn.edu/BMBB/faculty/Aihara.H.shtml
Start Date: January, 2010
Duration: 2 years
Description: A postdoctoral position will be open in January 2010 to conduct crystallographic studies of protein-DNA complexes. Our laboratory studies structure and function of various DNA-processing enzymes primarily using x-ray crystallography. Current research projects include retroviral integrases, tyrosine family of site-specific recombinases, and Holliday-junction resolvases. Successful candidate should have research experience (and Ph.D.) in biochemistry, biophysics, or similar disciplines. Prior experience with x-ray crystallography or other structural biology techniques is preferred. The University of Minnesota at Twin Cities offers superb research environment with state of the art x-ray diffraction and robotic crystallization facilities.
Please submit: CV & contact info of 3 references
Person to contact: Hideki Aihara
Surface mail address: 6-155 Jackson Hall, 321 Church Street S.E. Minneapolis, MN 55455
Email address: aihar001@umn.edu
Phone number: 612-624-1491
Job Posted: 09/17/09
Job ID Number: 1253213852
Postdoctoral researcher: protein crystallography and electron cryo-microscopy
University of Kansas
Department: Department of Molecular BiosciencesLocation: 1200 Sunnyside Ave., Lawrence, KS 66045
Start Date: Immediately
Duration: Up to 2 years, extensible
Description: An NIH-funded postdoctoral position is immediately available for a highly motivated individual with a strong interest in structure and function of macromolecular complexes in the laboratory of Dr. Liang Tang at the Department of Molecular Biosciences, University of Kansas (http://www.molecularbiosciences.ku.edu/faculty/tang.html). The projects include structural studies on protein complexes in the Type III secretion system and signal transduction in pathogenic bacteria by means of X-ray crystallography and electron cryo-microscopy. Multiple protein crystals are available and need to be optimized. The laboratory has easy access to a Rigaku RU-H3RHB X-ray generator with an R-axis IV++ imaging plate system and a 200kV FEI transmission electron microscope equipped with field emission gun both located in campus, and has regular access to synchrotron radiation beamlines. The position is funded up to two years, and may be extended dependent on performance and availability of funding. This position requires a Ph.D. in biochemistry or a related field, with a strong background in protein crystallography. For more information and to apply, go to: https://jobs.ku.edu and search with the job number 00004831. Review of applications has begun and will continue until the position is filled. EO/AA Employer.
Please submit: CV, 3 references, cover letter
Person to contact: Dr. Liang Tang
Surface mail address: Department of Molecular Biosciences, University of Kansas, 1200 Sunnyside Ave., Lawrence, KS 66045
Email address: tangl@ku.edu
Phone number: 785-864-5838
Fax number: 785-864-5294
Job Posted: 09/08/09
Job ID Number: 1252435110
Post doctoral position
University of Toronto
Location: Toronto, CanadaURL: http://www.sgc.utoronto.ca/Chromatin
Start Date: Immediately
Description: A Post-doctoral position in structural biology is available in the Chromatin biology and Epigenetic group at the Structural Genomics Consortium, University of Toronto. My lab aims to characterize proteins and Protein complexes involved in chromatin modification and gene regulation by X-ray crystallography in combination with other biochemical and biophysical techniques. Applicants should have a Ph.D. in structural biology, biochemistry, molecular/cell biology with 0-5 years postdoctoral research experience. Interested candidates are invited to send their CV with 3 references to:jr.min@utoronto.ca.
Person to contact: Jinrong Min
Email address: jr.min@utoronto.ca
Phone number: 416-9463868
Job Posted: 08/31/09
Job ID Number: 1251776781
Ph.D. Protein Crystallographer
Xtal BioStructures, Inc.
Location: Natick, MAURL: www.xtalbiostructures.com
Description: We seek an experienced crystallographer with post-doctoral experience to participate in a number of our diverse structural biology activities. These activities include: 1) structure-based drug design efforts; 2) structural analysis of protein therapeutic candidates; and 3) crystal structure analysis of proteins playing key roles in human disease. Candidates should have a wide range of active skills: protein crystallization and optimization, structure determination by molecular replacement, MIR and/or MAD methods, experience with a variety of computational programs, experience with home and synchrotron data collection, and ability to interpret and communicate structural information. Experience with any or all of the following is a plus: protein construct design; cloning, expression and purification of proteins; molecular modeling; and biophysical characterization (CD, ITC, SPR). The successful candidate will fit well into a collaborative environment and needs to exhibit strong leadership and excellent communication skills.
Please submit: CV
Surface mail address: 12 Michigan Dr., Natick, MA 01760
Email address: info@xtalbiostructures.com
Job Posted: 08/18/09
Job ID Number: 1250647436
Ph.D. Protein Crystallographer
Xtal BioStructures, Inc.
Location: Natick, MAURL: www.xtalbiostructures.com
Description: We seek an experienced crystallographer with post-doctoral experience to participate in a number of our diverse structural biology activities. These activities include: 1) structure-based drug design efforts; 2) structural analysis of protein therapeutic candidates; and 3) crystal structure analysis of proteins playing key roles in human disease. Candidates should have a wide range of active skills: protein crystallization and optimization, structure determination by molecular replacement, MIR and/or MAD methods, experience with a variety of computational programs, experience with home and synchrotron data collection, and ability to interpret and communicate structural information. Experience with any or all of the following is a plus: protein construct design; cloning, expression and purification of proteins; molecular modeling; and biophysical characterization (CD, ITC, SPR). The successful candidate will fit well into a collaborative environment and needs to exhibit strong leadership and excellent communication skills.
Please submit: CV
Surface mail address: 12 Michigan Dr., Natick, MA 01760
Email address: info@xtalbiostructures.com
Job Posted: 08/18/09
Job ID Number: 1250647398
A postdoctoral researcher, biological small-angle x-ray scattering
Stanford University
Department: Stanford Synchrotron Radiation Lightsource, SLAC Nat'l Accl LabLocation: Menlo Park, CA
Description: The Structural Molecular Biology group at SSRL, a Directorate of the SLAC National Accelerator Laboratory has an immediate opening for a postdoctoral researcher to join its biological small angle scattering/diffraction group. He/she will be involved in technological developments for solution x-ray scattering studies on proteins and macromolecular complexes as well as in-house and collaborative research projects, including molecular basis of neurodegenerative diseases. The initial term of appointment will be two years. Prior experience with x-ray scattering/diffraction experiments is desirable. We will also accept applications from qualified candidates trained in complementary computational or experimental techniques in molecular biophysics, physical biochemistry and structural biology. SLAC, located in Menlo Park, CA, adjacent to the Stanford University main campus on the San Francisco Peninsula, is a national laboratory operated by Stanford University for the US Department of Energy. Its proximity to first class academic institutions as well as industries in the San Francisco Bay Area promises young researchers an exceptional environment for professional growth.
Please submit: CV
Person to contact: Hiro Tsuruta
Surface mail address: 2575 Sand Hill Rd, Menlo Park, CA 94025-7015
Email address: tsuruta@stanford.edu
Phone number: 650 926 3104
Fax number: 650 926 4100
Job Posted: 08/18/09
Job ID Number: 1250636085
Postdoctoral Fellow - Membrane Protein Structure
Columbia University
Department: Department of Physiology and Cellular BiophysicsLocation: New York City, NY
URL: www.physiology.columbia.edu/structural.html
Start Date: Immediately
Description: We are seeking a talented and highly motivated Postdoctoral Fellow to work on the structure and function of eukaryotic membrane proteins associated with cardiovascular disease. The position is in a newly established laboratory within the Department of Physiology and Cellular Biophysics at Columbia University (NY). The successful candidate should ideally have experience in membrane protein expression, purification and/or structural biology techniques and a recent Ph.D. in biochemistry, biophysics or related discipline. The position is available immediately. Interested applicants should send their CV and a list of three references.
Please submit: CV and list of 3 references
Person to contact: Dr Filippo Mancia
Email address: fm123@columbia.edu
Phone number: (212) 3056082
Job Posted: 06/16/09
Job ID Number: 1245186263
Postdoctoral Fellow
The University of Western Ontario
Department: BiochemistryLocation: London, Ontario, Canada
URL: www.biochem.uwo.ca/fac/ling/ling.html
Start Date: ASAP
Duration: 2 year
Description: Postdoctoral positions in structural biology are available at Dr. Hong Ling's Laboratory in the Department of Biochemistry, University of Western Ontario, London, ON, Canada. The research in our lab is focused on structure-function studies of key proteins in translesion DNA replication and regulation of epigenetic factors. The current projects are built on our group’s previous success in structural determination of translesion proteins (PNAS 104: 14905-14910, 2007; Mol. Microbiol. 71: 678-691, 2009; EMBO J 28: 1644-1654, 2009) and the collaboration with other labs to expand the research in the Epigenome (Cell 128: 669-681, 693-705, 2007). For more information regarding the projects, please contact Dr. Hong Ling. The laboratory is fully equipped for molecular biology, biochemistry, biophysical measurements, and X-ray crystallography. We fully access the synchrotron beamlines in APS, CHESS, and NSLS. The University of Western Ontario (UWO) is one of the 12 research-intensive universities that receive operating funds from the Government of Canada. In the 2008 Globe and Mail (Canada's national newspaper) University Survey, UWO ranked No. 1 in student satisfaction and overall quality of education. The university has more than 30,000 students and a medical school that ranks among the top in the country. UWO is located in London, Ontario, Canada. London is a comfortable city (population: 350,000) with a reasonable cost of living and is close to major cities in eastern North America (two hours’ driving distance from Toronto). Qualified candidates should have experience in either Protein Crystallography or Biochemistry and Molecular Biology, with prior publications. Please send a CV and 3 references to Dr. Hong Ling by email at hling4@uwo.ca. For more information, please visit www.biochem.uwo.ca/fac/ling/ling.html
Other details: positions are open till filled
Person to contact: Dr. Hong Ling
Email address: hling4@uwo.ca
Phone number: 1 519 661 3557
Job Posted: 06/11/09
Job ID Number: 1244749491
POSTDOCTORAL FELLOW
RIKEN (The Institute of Physical and Chemical Research)
Department: Advanced Science InstituteLocation: Wako, Saitama, JAPAN
Start Date: ASAP
Description: POSTDOCTORAL FELLOW Position in Computational Structural Biology at the Zhang Initiative Research Unit, Advanced Science Institute, RIKEN, Japan We are seeking a highly motivated and experienced computational structural biologist to join the Zhang Initiative Research Unit at RIKEN. The successful candidate will use computational tools to tackle problems in the area of protein folding, structure prediction, crystallographic phasing or drug design. Qualifications: This position requires a PhD in biophysics, biochemistry, chemistry, bioinformatics or structural biology with experience in employing computational tools to solve biological or chemical problems. Experience in protein folding, protein structure prediction, protein structure analysis, protein crystallography or structure-based drug design are highly desired. Proficiency in object-oriented programming and scripting languages are also required. Experience in high performance computing, network computing or grid computing would be a plus. The ideal candidate should possess a track record of accomplishments demonstrating technical proficiency, independent thinking, and scientific creativity. The research environment in the unit is international and hence the ability to communicate in English is required. Salary and benefits: This is a full-time position with an annual renewable contract. Salary will be commensurate with qualification and experience. Commuting and housing allowance will be provided. Application and required documents: Complete CV (including list of publications) and names and contact information of three references.
Please submit: CV, 3 references
Person to contact: Kam Zhang, Ph.D
Surface mail address: Zhang Initiative Research Unit, Advanced Science Institute, RIKEN (The Institute of Physical and Chemical Research), 2-1 Hirosawa, Wako, Saitama 351-0198, Japan
Email address: zhang-unit@riken.jp
Phone number: +81-48-467-8792
Fax number: +81-48-467-8790
Job Posted: 06/04/09
Job ID Number: 1244103778
Postdoctoral fellow in Protein crystallography
University of California, Riverside
Department: BiochemistryLocation: Riverside, CA
Start Date: immediately
Duration: one year, renewable
Description: A postdoctoral position of protein X-ray crystallography is open immediately. The successful candidate will work on projects related to DNA damage response and DNA repair mechanism. We will apply cross-discipline methods in our research including X-ray crystallography, mutagenesis, biochemistry, and computational modeling/docking. State-of-the-art instruments for robotic crystal screening, imaging, and in-house data collection are available in the newly established protein crystallographic core facility within the department. The applicant must have a Ph.D. degree in life sciences or related disciplines. The successful candidate will have demonstrated record of strong skills in macromolecular X-ray crystallography. For application, please send a CV, list of publications and PDB codes for deposited coordinates, and names of three references to Dr. Li Fan by e-mail at lifan@ucr.edu.
Please submit: cv, cover letter, and at least 3 refs
Person to contact: Li Fan
Email address: lifan@ucr.edu
Phone number: 9518273630
Fax number: 9518274434
Job Posted: 05/29/09
Job ID Number: 1243630337
Postdoctoral Research Associate for Neutron Diffraction on HB-3A Four-Circle Diffractometer Instrument
Oak Ridge National Laboratory
Department: Neutron Scattering Science DivisionLocation: Oak Ridige, TN
URL: http://orise.orau.gov/sep/needs/files/ORNL09-82-NSSD.pdf
Start Date: ASAP
Description: Postdoctoral Research Associate for Neutron Diffraction on HB-3A Four-Circle Diffractometer Instrument Neutron Scattering Science Division Oak Ridge National Laboratory Oak Ridge, Tennessee ORNL09-82-NSSD Project Description: Responsibilities include conducting independent research using neutron diffraction as a primary research tool, mainly on the HFIR HB-3A Four-Circle Diffractometer, but also on other instruments at SNS and HFIR. Works with other members in the Neutron Scattering Science Division and collaborates with scientists in Divisions of Oak Ridge National Laboratory. Major Duties/Responsibilities: Conceives and conducts independent and collaborative neutron scattering experiments at HFIR and SNS, with emphasis on crystallography and magnetic crystal structures. • Participates in crystal growth experiments using solvothermal, flux growth, counter diffusion, and other methods as required. • Presents research results at scientific meetings and publishes research results in scientific journals. • Assists with the operation of the HB-3A Four-Circle Diffractometer instrument at HFIR. • Maintains a strong commitment to the implementation and perpetuation of values and ethics. • Ensures compliance with environment, safety, health and quality program requirements. Qualifications: Candidates with a recent Ph.D. in Physics, Chemistry, Materials Science, or related fields will be considered. Demonstrated expertise in the area of diffraction studies of condensed matter magnetism and/or small-molecule crystallography. Experience and knowledge with data acquisition systems and data analysis for single-crystal neutron diffraction are desirable. Strong written and oral communication skills and the desire to work in a team environment on scientifically challenging problems are required. Reports to the lead instrument scientist of HB-3A Four-Circle Diffractometer. Applicants cannot have received the most recent degree more than five years prior to the date of application and must complete all degree requirements before starting their appointment. Technical Questions: Contact Dr. Bryan Chakoumakos at chakoumakobc@ornl.gov. Please reference the position title and number when corresponding about this position. How to Apply: Qualified applicants must apply online at https://www2.orau.gov/ORNL_POST/. All applicants will need to register before they can begin the online application. For complete instructions, on how to apply, please see the instructions at http://www.orau.gov/orise/edu/ornl/ornl-pdpm/application.htm. When applying for this position, please reference the position title and number. This appointment is offered through the ORNL Postgraduate Research Participation Program and is administered by the Oak Ridge Institute for Science and Education (ORISE). The program is open to all qualified U.S. and non-U.S. citizens without regard to race, color, age, religion, sex, national origin, physical or mental disability, or status as a Vietnam-era veteran or disabled veteran.
Other details: This appointment is offered through the ORNL Postgraduate Research Participation Program and is administered by the Oak Ridge Institute for Science and Education (ORISE). The program is open to all qualified U.S. and non-U.S. citizens without regard to race, color, age, religion, sex, national origin, physical or mental disability, or status as a Vietnam-era veteran or disabled veteran.
Please submit: Online application
Person to contact: Dr. Bryan Chakoumakos
Surface mail address: n/a
Email address: chakoumakobc@ornl.gov
Phone number: n/a
Fax number: n/a
Job Posted: 05/21/09
Job ID Number: 1242924795
Postdoctoral Research Associate for Neutron Diffraction on HB-3A Four-Circle Diffractometer Instrument
Oak Ridge National Laboratory
Department: Neutron Scattering Science DivisionLocation: Oak Ridige, TN
URL: http://orise.orau.gov/sep/needs/files/ORNL09-82-NSSD.pdf
Start Date: ASAP
Description: Postdoctoral Research Associate for Neutron Diffraction on HB-3A Four-Circle Diffractometer Instrument Neutron Scattering Science Division Oak Ridge National Laboratory Oak Ridge, Tennessee ORNL09-82-NSSD Project Description: Responsibilities include conducting independent research using neutron diffraction as a primary research tool, mainly on the HFIR HB-3A Four-Circle Diffractometer, but also on other instruments at SNS and HFIR. Works with other members in the Neutron Scattering Science Division and collaborates with scientists in Divisions of Oak Ridge National Laboratory. Major Duties/Responsibilities: Conceives and conducts independent and collaborative neutron scattering experiments at HFIR and SNS, with emphasis on crystallography and magnetic crystal structures. • Participates in crystal growth experiments using solvothermal, flux growth, counter diffusion, and other methods as required. • Presents research results at scientific meetings and publishes research results in scientific journals. • Assists with the operation of the HB-3A Four-Circle Diffractometer instrument at HFIR. • Maintains a strong commitment to the implementation and perpetuation of values and ethics. • Ensures compliance with environment, safety, health and quality program requirements. Qualifications: Candidates with a recent Ph.D. in Physics, Chemistry, Materials Science, or related fields will be considered. Demonstrated expertise in the area of diffraction studies of condensed matter magnetism and/or small-molecule crystallography. Experience and knowledge with data acquisition systems and data analysis for single-crystal neutron diffraction are desirable. Strong written and oral communication skills and the desire to work in a team environment on scientifically challenging problems are required. Reports to the lead instrument scientist of HB-3A Four-Circle Diffractometer. Applicants cannot have received the most recent degree more than five years prior to the date of application and must complete all degree requirements before starting their appointment. Technical Questions: Contact Dr. Bryan Chakoumakos at chakoumakobc@ornl.gov. Please reference the position title and number when corresponding about this position. How to Apply: Qualified applicants must apply online at https://www2.orau.gov/ORNL_POST/. All applicants will need to register before they can begin the online application. For complete instructions, on how to apply, please see the instructions at http://www.orau.gov/orise/edu/ornl/ornl-pdpm/application.htm. When applying for this position, please reference the position title and number. This appointment is offered through the ORNL Postgraduate Research Participation Program and is administered by the Oak Ridge Institute for Science and Education (ORISE). The program is open to all qualified U.S. and non-U.S. citizens without regard to race, color, age, religion, sex, national origin, physical or mental disability, or status as a Vietnam-era veteran or disabled veteran.
Other details: This appointment is offered through the ORNL Postgraduate Research Participation Program and is administered by the Oak Ridge Institute for Science and Education (ORISE). The program is open to all qualified U.S. and non-U.S. citizens without regard to race, color, age, religion, sex, national origin, physical or mental disability, or status as a Vietnam-era veteran or disabled veteran.
Please submit: Online application
Person to contact: Dr. Bryan Chakoumakos
Surface mail address: n/a
Email address: chakoumakobc@ornl.gov
Phone number: n/a
Fax number: n/a
Job Posted: 05/21/09
Job ID Number: 1242924591
Postdoctoral Research Associate for Neutron Diffraction on HB-3A Four-Circle Diffractometer Instrument
Oak Ridge National Laboratory
Department: Neutron Scattering Science DivisionLocation: Oak Ridige, TN
URL: http://orise.orau.gov/sep/needs/files/ORNL09-82-NSSD.pdf
Start Date: ASAP
Description: Postdoctoral Research Associate for Neutron Diffraction on HB-3A Four-Circle Diffractometer Instrument Neutron Scattering Science Division Oak Ridge National Laboratory Oak Ridge, Tennessee ORNL09-82-NSSD Project Description: Responsibilities include conducting independent research using neutron diffraction as a primary research tool, mainly on the HFIR HB-3A Four-Circle Diffractometer, but also on other instruments at SNS and HFIR. Works with other members in the Neutron Scattering Science Division and collaborates with scientists in Divisions of Oak Ridge National Laboratory. Major Duties/Responsibilities: Conceives and conducts independent and collaborative neutron scattering experiments at HFIR and SNS, with emphasis on crystallography and magnetic crystal structures. • Participates in crystal growth experiments using solvothermal, flux growth, counter diffusion, and other methods as required. • Presents research results at scientific meetings and publishes research results in scientific journals. • Assists with the operation of the HB-3A Four-Circle Diffractometer instrument at HFIR. • Maintains a strong commitment to the implementation and perpetuation of values and ethics. • Ensures compliance with environment, safety, health and quality program requirements. Qualifications: Candidates with a recent Ph.D. in Physics, Chemistry, Materials Science, or related fields will be considered. Demonstrated expertise in the area of diffraction studies of condensed matter magnetism and/or small-molecule crystallography. Experience and knowledge with data acquisition systems and data analysis for single-crystal neutron diffraction are desirable. Strong written and oral communication skills and the desire to work in a team environment on scientifically challenging problems are required. Reports to the lead instrument scientist of HB-3A Four-Circle Diffractometer. Applicants cannot have received the most recent degree more than five years prior to the date of application and must complete all degree requirements before starting their appointment. Technical Questions: Contact Dr. Bryan Chakoumakos at chakoumakobc@ornl.gov. Please reference the position title and number when corresponding about this position. How to Apply: Qualified applicants must apply online at https://www2.orau.gov/ORNL_POST/. All applicants will need to register before they can begin the online application. For complete instructions, on how to apply, please see the instructions at http://www.orau.gov/orise/edu/ornl/ornl-pdpm/application.htm. When applying for this position, please reference the position title and number. This appointment is offered through the ORNL Postgraduate Research Participation Program and is administered by the Oak Ridge Institute for Science and Education (ORISE). The program is open to all qualified U.S. and non-U.S. citizens without regard to race, color, age, religion, sex, national origin, physical or mental disability, or status as a Vietnam-era veteran or disabled veteran.
Other details: This appointment is offered through the ORNL Postgraduate Research Participation Program and is administered by the Oak Ridge Institute for Science and Education (ORISE). The program is open to all qualified U.S. and non-U.S. citizens without regard to race, color, age, religion, sex, national origin, physical or mental disability, or status as a Vietnam-era veteran or disabled veteran.
Please submit: Online application
Person to contact: Dr. Bryan Chakoumakos
Surface mail address: n/a
Email address: chakoumakobc@ornl.gov
Phone number: n/a
Fax number: n/a
Job Posted: 05/21/09
Job ID Number: 1242924535
Postdoctoral Research Associate for Neutron Diffraction on HB-3A Four-Circle Diffractometer Instrument
Oak Ridge National Laboratory
Department: Neutron Scattering Science DivisionLocation: Oak Ridige, TN
URL: http://orise.orau.gov/sep/needs/files/ORNL09-82-NSSD.pdf
Start Date: ASAP
Description: Postdoctoral Research Associate for Neutron Diffraction on HB-3A Four-Circle Diffractometer Instrument Neutron Scattering Science Division Oak Ridge National Laboratory Oak Ridge, Tennessee ORNL09-82-NSSD Project Description: Responsibilities include conducting independent research using neutron diffraction as a primary research tool, mainly on the HFIR HB-3A Four-Circle Diffractometer, but also on other instruments at SNS and HFIR. Works with other members in the Neutron Scattering Science Division and collaborates with scientists in Divisions of Oak Ridge National Laboratory. Major Duties/Responsibilities: Conceives and conducts independent and collaborative neutron scattering experiments at HFIR and SNS, with emphasis on crystallography and magnetic crystal structures. • Participates in crystal growth experiments using solvothermal, flux growth, counter diffusion, and other methods as required. • Presents research results at scientific meetings and publishes research results in scientific journals. • Assists with the operation of the HB-3A Four-Circle Diffractometer instrument at HFIR. • Maintains a strong commitment to the implementation and perpetuation of values and ethics. • Ensures compliance with environment, safety, health and quality program requirements. Qualifications: Candidates with a recent Ph.D. in Physics, Chemistry, Materials Science, or related fields will be considered. Demonstrated expertise in the area of diffraction studies of condensed matter magnetism and/or small-molecule crystallography. Experience and knowledge with data acquisition systems and data analysis for single-crystal neutron diffraction are desirable. Strong written and oral communication skills and the desire to work in a team environment on scientifically challenging problems are required. Reports to the lead instrument scientist of HB-3A Four-Circle Diffractometer. Applicants cannot have received the most recent degree more than five years prior to the date of application and must complete all degree requirements before starting their appointment. Technical Questions: Contact Dr. Bryan Chakoumakos at chakoumakobc@ornl.gov. Please reference the position title and number when corresponding about this position. How to Apply: Qualified applicants must apply online at https://www2.orau.gov/ORNL_POST/. All applicants will need to register before they can begin the online application. For complete instructions, on how to apply, please see the instructions at http://www.orau.gov/orise/edu/ornl/ornl-pdpm/application.htm. When applying for this position, please reference the position title and number. This appointment is offered through the ORNL Postgraduate Research Participation Program and is administered by the Oak Ridge Institute for Science and Education (ORISE). The program is open to all qualified U.S. and non-U.S. citizens without regard to race, color, age, religion, sex, national origin, physical or mental disability, or status as a Vietnam-era veteran or disabled veteran.
Please submit: Online application
Person to contact: Dr. Bryan Chakoumakos
Email address: chakoumakobc@ornl.gov
Job Posted: 05/21/09
Job ID Number: 1242924487
Postdoctoral Research Associate for Neutron Diffraction on HB-3A Four-Circle Diffractometer Instrument
Oak Ridge National Laboratory
Department: Neutron Scattering Science DivisionLocation: Oak Ridige, TN
URL: http://orise.orau.gov/sep/needs/files/ORNL09-82-NSSD.pdf
Start Date: ASAP
Description: Postdoctoral Research Associate for Neutron Diffraction on HB-3A Four-Circle Diffractometer Instrument Neutron Scattering Science Division Oak Ridge National Laboratory Oak Ridge, Tennessee ORNL09-82-NSSD Project Description: Responsibilities include conducting independent research using neutron diffraction as a primary research tool, mainly on the HFIR HB-3A Four-Circle Diffractometer, but also on other instruments at SNS and HFIR. Works with other members in the Neutron Scattering Science Division and collaborates with scientists in Divisions of Oak Ridge National Laboratory. Major Duties/Responsibilities: Conceives and conducts independent and collaborative neutron scattering experiments at HFIR and SNS, with emphasis on crystallography and magnetic crystal structures. • Participates in crystal growth experiments using solvothermal, flux growth, counter diffusion, and other methods as required. • Presents research results at scientific meetings and publishes research results in scientific journals. • Assists with the operation of the HB-3A Four-Circle Diffractometer instrument at HFIR. • Maintains a strong commitment to the implementation and perpetuation of values and ethics. • Ensures compliance with environment, safety, health and quality program requirements. Qualifications: Candidates with a recent Ph.D. in Physics, Chemistry, Materials Science, or related fields will be considered. Demonstrated expertise in the area of diffraction studies of condensed matter magnetism and/or small-molecule crystallography. Experience and knowledge with data acquisition systems and data analysis for single-crystal neutron diffraction are desirable. Strong written and oral communication skills and the desire to work in a team environment on scientifically challenging problems are required. Reports to the lead instrument scientist of HB-3A Four-Circle Diffractometer. Applicants cannot have received the most recent degree more than five years prior to the date of application and must complete all degree requirements before starting their appointment. Technical Questions: Contact Dr. Bryan Chakoumakos at chakoumakobc@ornl.gov. Please reference the position title and number when corresponding about this position. How to Apply: Qualified applicants must apply online at https://www2.orau.gov/ORNL_POST/. All applicants will need to register before they can begin the online application. For complete instructions, on how to apply, please see the instructions at http://www.orau.gov/orise/edu/ornl/ornl-pdpm/application.htm. When applying for this position, please reference the position title and number. This appointment is offered through the ORNL Postgraduate Research Participation Program and is administered by the Oak Ridge Institute for Science and Education (ORISE). The program is open to all qualified U.S. and non-U.S. citizens without regard to race, color, age, religion, sex, national origin, physical or mental disability, or status as a Vietnam-era veteran or disabled veteran.
Please submit: Online application
Person to contact: Dr. Bryan Chakoumakos
Email address: chakoumakobc@ornl.gov
Job Posted: 05/21/09
Job ID Number: 1242924479
Postdoctoral Research Associate for Neutron Diffraction on HB-3A Four-Circle Diffractometer Instrument
Oak Ridge National Laboratory
Department: Neutron Scattering Science DivisionLocation: Oak Ridige, TN
URL: http://orise.orau.gov/sep/needs/files/ORNL09-82-NSSD.pdf
Start Date: ASAP
Description: Postdoctoral Research Associate for Neutron Diffraction on HB-3A Four-Circle Diffractometer Instrument Neutron Scattering Science Division Oak Ridge National Laboratory Oak Ridge, Tennessee ORNL09-82-NSSD Project Description: Responsibilities include conducting independent research using neutron diffraction as a primary research tool, mainly on the HFIR HB-3A Four-Circle Diffractometer, but also on other instruments at SNS and HFIR. Works with other members in the Neutron Scattering Science Division and collaborates with scientists in Divisions of Oak Ridge National Laboratory. Major Duties/Responsibilities: Conceives and conducts independent and collaborative neutron scattering experiments at HFIR and SNS, with emphasis on crystallography and magnetic crystal structures. • Participates in crystal growth experiments using solvothermal, flux growth, counter diffusion, and other methods as required. • Presents research results at scientific meetings and publishes research results in scientific journals. • Assists with the operation of the HB-3A Four-Circle Diffractometer instrument at HFIR. • Maintains a strong commitment to the implementation and perpetuation of values and ethics. • Ensures compliance with environment, safety, health and quality program requirements. Qualifications: Candidates with a recent Ph.D. in Physics, Chemistry, Materials Science, or related fields will be considered. Demonstrated expertise in the area of diffraction studies of condensed matter magnetism and/or small-molecule crystallography. Experience and knowledge with data acquisition systems and data analysis for single-crystal neutron diffraction are desirable. Strong written and oral communication skills and the desire to work in a team environment on scientifically challenging problems are required. Reports to the lead instrument scientist of HB-3A Four-Circle Diffractometer. Applicants cannot have received the most recent degree more than five years prior to the date of application and must complete all degree requirements before starting their appointment. Technical Questions: Contact Dr. Bryan Chakoumakos at chakoumakobc@ornl.gov. Please reference the position title and number when corresponding about this position. How to Apply: Qualified applicants must apply online at https://www2.orau.gov/ORNL_POST/. All applicants will need to register before they can begin the online application. For complete instructions, on how to apply, please see the instructions at http://www.orau.gov/orise/edu/ornl/ornl-pdpm/application.htm. When applying for this position, please reference the position title and number. This appointment is offered through the ORNL Postgraduate Research Participation Program and is administered by the Oak Ridge Institute for Science and Education (ORISE). The program is open to all qualified U.S. and non-U.S. citizens without regard to race, color, age, religion, sex, national origin, physical or mental disability, or status as a Vietnam-era veteran or disabled veteran.
Please submit: Online application
Person to contact: Dr. Bryan Chakoumakos
Email address: chakoumakobc@ornl.gov
Job Posted: 05/21/09
Job ID Number: 1242924455
Computing & X-Ray Scientist
St. Jude Children's Research Hospital
Location: Memphis, TennesseeURL: www.stjude.org/jobs
Description:
Computing & X-Ray Scientist
Memphis, TN
St. Jude Children's Research Hospital, located in Memphis, Tennessee, is a premier center for research and treatment of potentially fatal childhood diseases, including cancer and certain blood, genetic, and immunodeficiency disorders. The hospital's mission is to advance cures, and means of prevention, for pediatric catastrophic diseases through research and treatment. St. Jude is dedicated to providing unsurpassed patient care and to advancing the health of children through biomedical research.
Currently, St. Jude Children's Research Hospital has an opening for a Computing & X-Ray Scientist (Job Number 17868).
The Computing & X-Ray Scientist oversees the day-to-day operation of the computing and X-ray facilities that support the research in the Department of Structural Biology and collaborations with researchers throughout the institution, notably in the Department of Chemical Biology and Therapeutics. The selected candidate will work with ITS personnel to maintain and backup the computing infrastructure within the department, install software as necessary, and maintain computer networks. The candidate will work with the manufacturer of the X-ray equipment to solve hardware and software problems, and performs routine maintenance of the equipment. Acquire knowledge relevant to biophysical computing and X-ray crystallography. Perform other related duties as assigned or directed to meet the goals and objectives of the department.
Requirements:
- Ph.D. in an appropriate scientific field required.
- 5 years of experience in structural biology, computing and/or a related field is required.
- Expertise in LINUX/OSX systems administration and all aspects of macromolecular crystallography including the use and implementation of crystallographic software packages, data collection and processing, and structure determination and refinement required.
- Experience in the maintenance of in-house X-ray equipment preferred.
St. Jude offers a positive working culture, professional advancement, & competitive compensation. Qualified applicants may apply for this position or others via our online process at: www.stjude.org/jobs
www.stjude.org
An Equal Opportunity Employer
Job Posted: 04/06/09
Job ID Number: 1239052599
Postdoctoral Fellow and Research Associate
Boston University School of Medicine
Department: Physiology and BiophysicsLocation: Boston, Mass
URL: biophysics.bumc.bu.edu/faculty/guo/index.html
Start Date: immediately
Duration: 1-3 years
Description: Two positions (one postdoctoral fellow and one research associate) are open for highly motivated individuals to work on biochemical and crystallographic studies of enzymes involved in post-translational processings and immunity. Some crystals are already available. The work may involve any aspect of protein purification, mutagenesis, crystal growth, data collection, model building and refinement. Suitable candidates will also have the chance to participate in the biochemical characterization of the proteins. A background in protein expression/biochemistry and/or x-ray structure determination is prerequisite. Experienced macromolecular crystallographers are preferred, but highly motivated recent graduates (PhD or BS/MS degree) with a strong background in protein biochemistry and interested in learning crystallography are also encouraged to apply. The laboratory is fully equipped for biochemical experiments, and with state-of-the-art crystallographic facilities. In addition, the National Synchrotron Light Source at the Brookhaven National Laboratory is only 4-hour driving away. Available immediately, applications will be accepted till positions filled.
Other details: Equal Opportunity Employer
Please submit: Cover letter with curriculum vita and the names and addresses (including e-mail addresses) of three referees
Person to contact: Dr. Hwai-Chen Guo
Surface mail address: 700 Albany Street, Boston, MA 02118
Email address: hcguo@bu.edu
Phone number: 617-638-4023
Job Posted: 03/27/09
Job ID Number: 1238179448
Crystallography of enzyme-RNA complexes
University of California at Santa Barbara
Department: Chemistry & BiochemistryLocation: Santa Barbara, CA
URL: www.chem.ucsb.edu/peoplefaculty/perona
Start Date: May 1 2009
Duration: 2 years or longer
Description: POSTDOCTORAL POSITION - ENZYME-RNA INTERACTIONS An NIH-funded postdoctoral position is available immediately for the detailed characterization of enzyme-tRNA complexes by Xray crystallography. Projects include work on aminoacyl-tRNA synthetases, tRNA-dependent amino acid-modifying enzymes, and tRNA-modifying enzymes. Projects encompass both de novo structure determinations and detailed structure-function studies. This position provides an opportunity to integrate Xray crystallography with enzymology, including rapid chemical quench and fluorescence approaches. Experience in macromolecular crystallography is required. Preference given to individuals with a background in nucleic acid biochemistry. Contact: Dr. John Perona, perona@chem.ucsb.edu
Please submit: CV and names of 2 references.
Person to contact: Dr John Perona
Surface mail address: Department of Chemistry & Biochemistry, University of California at Santa Barbara, Santa Barbara CA 93106-9510
Email address: perona@chem.ucsb.edu
Phone number: 805-893-7389
Fax number: 805-893-4120
Job Posted: 03/25/09
Job ID Number: 1238006223
Postdoctoral Fellow , Membrane Protein Structural Biology
Genomics Institute of the Novartis Research Foundation
Department: Structural BiologyLocation: San Diego, USA
URL: www.gnf.org
Start Date: Immediately
Description: We are seeking talented and highly motivated Postdoctoral Fellows to work within the Structural Biology Department of GNF on the structure and function of eukaryotic membrane proteins associated with human disease. Projects will utilize GNF’s state of the art robotic eukaryotic protein expression, bio-analytic, crystallization and X-ray data collection systems to investigate and determine the structures of novel membrane proteins. The position provides a unique opportunity to conduct research in an exceptional multi-disciplinary environment studying many aspects of the biological sciences from pure biology to translational drug discovery research. The successful candidate should ideally have experience in membrane protein expression, purification and analysis, a desire to learn structural biology techniques and a recent Ph.D. in biochemistry, biophysics or related discipline. Good communication skills and the ability to work in a team are essential. Applications or informal enquiries should be directed to G. Spraggon gspraggon@gnf.org and Andreas Kreusch akreusch@gnf.org 10675 John Jay Hopkins Drive San Diego, CA 92121 The Genomics Institute of the Novartis Research Foundation (GNF) located in the Torrey Pines area of San Diego, CA focuses on paradigm-shifting technologies, making possible new approaches to complex biomedical problems. Pioneering technology platforms in genomics, proteomics, chemistry, structural biology, computation biology and engineering have been established as part of an integrated, multidisciplinary approach to biomedical research and drug discovery. The mission is to develop and apply innovative technologies to the discovery of new biological processes and a detailed understanding of their underlying molecular mechanisms ultimately leading to new or improved human therapeutics. Currently the institute consists of approximately 500 scientist dedicated to various areas such as Neurobiology, Cancer Biology, Immunology, Metabolic/Cardiovascular and Infectious Disease. Visit our website: http://www.gnf.org for complete list of employment opportunities. GNF offers excellent compensation and a great benefits package.
Person to contact: Andreas Kreusch and Glen Spraggon
Surface mail address: 10675 John Jay Hopkins Drive, San Diego, CA 92121
Email address: akreusch@gnf.org, gspraggo@gnf.org
Phone number: 858 812 1890
Job Posted: 03/17/09
Job ID Number: 1237326035
Postdoctoral Research Associate
New Haven
URL: http://info.med.yale.edu/pharm/faculty/index.php?bioID=9Description: A postdoctoral position is available for an NIH-sponsored study of Alzheimer's amyloid precursor protein (APP) and its disease-causing fragment. Although we use x-ray crystallography as the primary experimental tool, this project also involves monoclonal antibodies, binding studies, and extensive modeling and mutagenesis. Therefore, we prefer applicants who have substantial training in molecular biology, chrome, biochemistry and biophysics.
Person to contact: Ya Ha, Associate Professor of Pharmacology
Surface mail address: ya.ha@yale.edu
Email address: ya.ha@yale.edu
Phone number: 203-785-7530
Fax number: 203-785-7670
Job Posted: 03/09/09
Job ID Number: 1236627665
Associate Research Scientist
Columbia University
Department: BiologyLocation: New York, NY
URL: www.nesg.org
Start Date: immediate
Description: An accomplished and dynamic senior scientist is sought to join the high-throughput protein biochemistry / crystallography group of the Northeast Structural Genomics Consortium (www.nesg.org) at Columbia University. The successful applicant will be appointed as an Associate Research Scientist and will participate in cutting-edge projects directed at using structural information to elucidate the function of uncharacterized protein families as well as engineering proteins for improved crystallization. A track-record in successfully crystallizing proteins is essential, and experience solving structures is a plus. Preference will be given to candidates with expertise in crystallizing protein complexes with nucleic acids. A PhD in a related field and at least three years of post-doctoral experience in protein crystallization / crystallography are required. Salary commensurate with experience. Contact Philip Manor at PM2047@Columbia.edu.
Person to contact: Philip Manor
Surface mail address: 1212 Amsterdam Ave., MC 2437, NY, NY 10027
Email address: PM2047@columbia.edu
Phone number: 212-854-4936
Job Posted: 03/05/09
Job ID Number: 1236275491
Postdoctoral Research Fellows - Drug Discovery
Moffitt Cancer Center
Department: Drug DiscoveryLocation: Tampa, FL
URL: tbe.taleo.net/NA4/ats/careers/requisition.jsp?org=MOFFITT&cws=1&rid=4415
Description: Postdoctoral positions are available to study the structure and function of diverse drug targets in the laboratory of Dr. Ernst Schönbrunn at H. Lee Moffitt Cancer Center and Research Institute. This is a post-graduate entry-level position in which the individual is responsible for assisting with research activities as well as conducting independent research projects when appropriate under limited supervision. The successful candidate will perform experiments on various medicinally important proteins to discover novel inhibitors with potential as drugs. This position entails the cloning, large scale purification and characterization of recombinant proteins. Depending on interests and skills, the successful candidate will be provided with the opportunity to expand his/her expertise in methods relevant to drug discovery such as molecular modeling, enzyme kinetics, high-throughput screening and protein crystallography. Qualified candidates should have a PhD or equivalent degree in Biology, Biochemistry, Chemistry or related field with a background in molecular biology and/or protein chemistry. Extensive experience in DNA recombinant technology and large-scale purification of proteins is required. Experience in macromolecular crystallography and/or enzyme kinetics is highly desirable. Excellent verbal and written communication skills are required. The H. Lee Moffitt Comprehensive Cancer Center is a modern facility on the University of South Florida Campus that conducts research on various aspects of Cancer Biology with emphasis on translational research. It is the third largest Cancer Center in the US based on patient volume. Research environment includes state of the art modern core facilities and pathogen-free modern animal facilities, access to clinical material, etc. Please apply online at www.moffitt.org/careers to REQ ID 4415 and send CV, cover letter, and the names and contact information of three references to Dr. Ernst Schönbrunn via email at Joy.DeComarmond@moffitt.org.
Please submit: CV, cover letter, and the names and contact information of three references
Person to contact: Dr. Ernst Schönbrunn
Email address: Joy.DeComarmond@moffitt.org
Job Posted: 02/25/09
Job ID Number: 1235582400
Postdoctoral Research Fellows - Drug Discovery
Moffitt Cancer Center
Department: Drug DiscoveryLocation: Tampa, FL
URL: tbe.taleo.net/NA4/ats/careers/requisition.jsp?org=MOFFITT&cws=1&rid=4415
Description: Postdoctoral positions are available to study the structure and function of diverse drug targets in the laboratory of Dr. Ernst Schönbrunn at H. Lee Moffitt Cancer Center and Research Institute. This is a post-graduate entry-level position in which the individual is responsible for assisting with research activities as well as conducting independent research projects when appropriate under limited supervision. The successful candidate will perform experiments on various medicinally important proteins to discover novel inhibitors with potential as drugs. This position entails the cloning, large scale purification and characterization of recombinant proteins. Depending on interests and skills, the successful candidate will be provided with the opportunity to expand his/her expertise in methods relevant to drug discovery such as molecular modeling, enzyme kinetics, high-throughput screening and protein crystallography. Qualified candidates should have a PhD or equivalent degree in Biology, Biochemistry, Chemistry or related field with a background in molecular biology and/or protein chemistry. Extensive experience in DNA recombinant technology and large-scale purification of proteins is required. Experience in macromolecular crystallography and/or enzyme kinetics is highly desirable. Excellent verbal and written communication skills are required. The H. Lee Moffitt Comprehensive Cancer Center is a modern facility on the University of South Florida Campus that conducts research on various aspects of Cancer Biology with emphasis on translational research. It is the third largest Cancer Center in the US based on patient volume. Research environment includes state of the art modern core facilities and pathogen-free modern animal facilities, access to clinical material, etc. Please apply online at www.moffitt.org/careers to REQ ID 4415 and send CV, cover letter, and the names and contact information of three references to Dr. Ernst Schönbrunn via email at Joy.DeComarmond@moffitt.org.
Please submit: CV, cover letter, and the names and contact information of three references
Person to contact: Dr. Ernst Schönbrunn
Email address: Joy.DeComarmond@moffitt.org
Job Posted: 02/25/09
Job ID Number: 1235582374
PDF position
Hospital for Sick Children/University of Toronto
Department: Program in Molecular Structure & FunctionLocation: Toronto, Canada
URL: www.sickkids.ca/research/HowellLab/
Start Date: May 1, 2009
Description: A postdoctoral position is available at The Hospital for Sick Children/University of Toronto to continue our structure-function studies on the polymerization, modification and export of alginate, an exopolysaccharide produced by the opportunistic pathogen Pseudomonas aeruginosa and involved in biofilm formation in the lungs of Cystic Fibrosis patients. While exopolysaccharide biosynthesis and secretion has long been a focus of investigation within the microbiology community, the molecular mechanisms by which multi-protein complexes facilitate export of these polymers are still poorly understood. The position available is ideally suited to a highly motivated and energetic individual who is keen to work in a multi-disciplinary environment involving both microbiology and structural biology research, and has an interest in protein-protein interactions and/or cellular export processes. The successful candidate must have a PhD degree in a relevant field and previous research experience in either protein crystallography, the study of protein-protein interactions and/or microbiology. A strong background in molecular biology and protein chemistry would be an asset. Toronto is the most culturally diverse city in North America and home to one of the largest Structural Biology communities worldwide . With investigators specializing in protein crystallography, NMR spectroscopy, electron microscopy, computational chemistry, and protein folding and design, the city provides a stimulating environment for learning and practicing the techniques of modern structural biology. The position is available May 1, 2009 with funding for a qualified candidate for at least 3 years. Interested candidates should send a CV including a description of research experience(s) and the names of three professional references to: Dr. P. Lynne Howell at howell@sickkids.ca.
Please submit: CV and names of 3 professinal references
Person to contact: P. Lynne Howell
Email address: howell@sickkids.ca
Job Posted: 02/23/09
Job ID Number: 1235414782
Post-doctoral Research Associate
Columbia University
Department: Biological SciencesLocation: New York City
URL: como.bio.columbia.edu/tong/
Start Date: immediately
Description: Two Post-doctoral Research Associate positions are available for structural studies on enzymes involved in fatty acid metabolism or proteins involved in pre-mRNA 3'-end processing. We have extensive experience in these areas, and have produced many high-impact publications. Please see my home page for more information. Strong experience in protein biochemistry is required. Prior experience with X-ray crystallography is desirable. The successful candidates will be eligible for subsidized Columbia University housing. In addition to research in the laboratory, you will also be able to experience the excitement of New York City life, and have your own bite of the Big Apple.
Please submit: CV and names of three references
Person to contact: Liang Tong
Surface mail address: Dept. of Biological Sciences, Columbia University, New York, NY 10027
Email address: ltong@columbia.edu
Job Posted: 02/17/09
Job ID Number: 1234888200
Postdoctoral Fellow
Yale University
Department: PharmacologyLocation: New Haven, CT
URL: http://info.med.yale.edu/pharm/faculty/index.php?bioID=14
Start Date: Immediately
Description: A POSTDOCTORAL POSITION at the Yale University School of Medicine is available for a multidisciplinary and collaborative research project. Both human thymidylate synthase (TS) and dihydrofolate reductase (DHFR) are targets of cancer therapy due to their importance in DNA biosynthesis and DNA repair (for TS) and for de novo synthesis of purines and pyrimidines as well as the synthesis of certain amino acids (for DHFR). The binding of these proteins to their mRNA inhibits translation providing a mechanism of auto-regulation. In addition to the structural source of these interactions, we are also interested in understanding the mechanism by which binding of mRNA inhibits enzymatic activity (competitive, non-competitive, or uncompetitive). Training and experience in biochemistry and X-ray crystallography is required.
Please submit: CV and three references
Person to contact: Nicole Colon, Elias Lolis
Surface mail address: Department of Pharmacology, Yale University, 333 Cedar St., New Haven, CT 06520
Email address: nicole.colon@yale.edu, elias.lolis@yale.edu
Phone number: 203-785-7469
Job Posted: 02/05/09
Job ID Number: 1233871553
Postdoctoral Fellow
Lerner Research Institute, Cleveland Clinic
Department: PathobiologyLocation: Cleveland, Ohio, USA
URL: www.lerner.ccf.org/pathobio/stuehr/
Start Date: 2009
Duration: NA
Description: A Post-Doctoral fellowship is available immediately in the lab of Dr. Dennis Stuehr for those who have an interest in mechanism, structure-function, and regulation of redox enzymes at the molecular level. The successful applicant will join a multi-disciplinary protein structure-function lab. Our lab is fully equipped for molecular and cell biology, protein expression & purification, conventional & pre-steady-state kinetic studies (stopped flow spectroscopy, rapid freeze, and chemical quench), computational work, & through on-site collaborators protein crystallization, hydrogen-deuterium exchange mass spectrometry, NMR, and binding studies using ITC and surface plasmon resonance. Candidates with experience in protein crystallization or protein HxD mass spectrometry are particularly encouraged to apply. Salary is commensurate with NIH guidelines and applicant experience.
Please submit: Cover letter, CV, 3 references
Person to contact: Dr. Dennis Stuehr
Surface mail address: Lerner Institute NC2, 9500 Euclid Ave., Cleveland, OH 44195
Email address: stuehrd@ccf.org
Phone number: 216-445-6950
Fax number: 216-636-0104
Job Posted: 02/05/09
Job ID Number: 1233850543
Postdoctoral Fellow
Samuel Roberts Noble Foundation
Department: Plant Biology DivisionLocation: Ardmore, Oklahoma
URL: www.noble.org/PlantBio/
Start Date: ASAP
Description: A postdoctoral position is available in the laboratory of Dr. Xiaoqiang Wang in the Plant Biology Division at the Samuel Roberts Noble Foundation. The research is to study the structure and function of enzymes involved in plant natural product biosynthesis, and nucleic acid binding proteins and the mechanisms of gene regulation. The lab is well equipped with state-of-the-art equipment for molecular biology, protein biochemistry, and crystallography, including two AKTAPurifers, Phoenix crystallization robot and an R-AXIS IV++ detector with a RU-H3R rotating anode generator and X-stream cryosystem. Applicants should have a Ph.D. with experience in crystallography and protein expression and purification. Salary begins at $41,200 and commensurate with experience, plus excellent benefits. Informal inquiries can be made to Dr. Wang (Email: xwang@noble.org, Tel: 580-2246720). Applicants are requested to apply online by completing the application and submitting a resume and contact information for three references. Applications will be accepted until a candidate is hired. Interested applicants should apply at www.noble.org/Jobs/WebsiteEmployment/ (Position Number: PB-S065-56).
Please submit: CV, list of references
Person to contact: Dr. Xiaoqiang Wang
Surface mail address: Samuel Roberts Noble Foundation, Plant Biology Division, P.O. Box 2180, Ardmore, OK 73402
Email address: xwang@noble.org
Phone number: 580-2246720
Fax number: 580-2246692
Job Posted: 02/02/09
Job ID Number: 1233616069
Postdoctoral position
Baylor College of Medicine
Department: PharmacologyLocation: Houston, Texas
URL: http://www.bcm.edu/pharmacology/index.cfm?pmid=9685
Start Date: ASAP
Description: We are seeking a talented and motivated individual to join the Structural Biology Group in the Department of Pharmacology at Baylor School of Medicine (Vacancy number at BCM job site:175287AC). We study-function relationship of proteins in NO/cGMP signaling pathway. We use a highly interdisciplinary approach including x-ray crystallography, NMR, yeast genetics and biochemistry. The laboratory is surrounded in an interdisciplinary research environment and equipped with state-of-the-art instruments for high-throughput crystallography. These include a Mosquito, liquid handling robot complete with an automated imaging system and Rigaku MicroMax 007 generator with have high flux mirrors and R-AXIS detector. The successful candidates must have PhD degree in structural biology and experience in protein chemistry and macromolecular crystallography. Applicants should apply at BCM job site https://www.medschooljobs.org using Vacancy number, 175287AC. Alternatively send curriculum vitae, a brief statement of research accomplishments and interests, and names of three references to: andrewm@bcm.tmc.edu. The position is available immediately for one year with the possibility of extension for subsequent years. Competitive salary will be commensurate with experience and qualification.
Please submit: CV and three references
Person to contact: Andrew McCullough
Surface mail address: andrewm@bcm.tmc.edu
Email address: ckim@bcm.edu
Phone number: 713-798-8411
Job Posted: 01/30/09
Job ID Number: 1233356516
post doc or staff scientist
Vanderbilt University Medical Center
Department: PharmacologyLocation: Nashville, TN
URL: medschool.mc.vanderbilt.edu/facultydata/php_files/show_faculty.php?id3=16208
Start Date: immediately
Description: Dear CCP4 Users, We have an opening for one federally funded post-doctoral position for a structural biologist or protein biochemist to study bacterial voltage-gated sodium channels. The ideal candidate will be self-motivated, creative, organized, and experienced in crystallography or protein biochemistry. The lab is a structural biology group within the department of Pharmacology at the Vanderbilt University medical center in Nashville, TN. Nashville combines the features of a college town with those of a fairly large city. Urban amenities include restaurants, museums, theatres, music, yet the cost of living is moderate and the city is very livable. Please email questions, CV’s, and references to Ben Spiller: [log in to unmask]
Please submit: cv, list of references
Person to contact: Ben Spiller
Email address: benjamin.spiller@vanderbilt.edu
Job Posted: 01/07/09
Job ID Number: 1231366999
Postdoctoral position
Oregon Health and Science University
Department: Physiology and PharmacologyLocation: Portland, Oregon
URL: www.ohsu.edu/ohsuedu/academic/som/physpharm/faculty/valiyaveetil-lab.cfm
Start Date: flexible
Duration: 04-01-2009
Description: A postdoctoral position is available immediately in a research group applying unnatural amino acid mutagenesis, structural biology and electrophysiology to the study of ion channel structure and function. Novel methods for the semi-synthesis of membrane protein will be applied to the study of potassium-selective channels and other medically relevant membrane proteins, (Valiyaveetil, F. I. et. al. Science, 2006, 314, 1004-7, Valiyaveetil, F. I. et. al. J. Am. Chem. Soc., 2006, 128, 11591-9). The laboratory provides the opportunity to gain experience in unnatural amino acid mutagenesis and protein semi-synthesis. A Ph.D. in biochemistry, biophysics or a related discipline is required. Practical experience with structural biology or membrane protein biochemistry is desired but not essential.
Please submit: CV and names of 3 references
Person to contact: Francis Valiyaveetil
Surface mail address: 3181 SW Sam Jackson Park Road, Mail code: L334, Dept. of Physiology and Pharmacology
Email address: valiyave@ohsu.edu
Phone number: 503-418-0946
Job Posted: 01/05/09
Job ID Number: 1231217876
Senior Auditor - Global Clinical Audits
Schering Plough
Department: Schering PloughLocation: Kenilworth, NJ
URL: http://appclix.postmasterlx.com/track.html?pid=402881bd1e48ea6f011e4b9cc7ca0684&source=crystallographic
Start Date: 12/19/2008
Description: Schering-Plough is an innovation-driven, science-centered global health care company. Through our own biopharmaceutical research and collaborations with partners, we create therapies that help save and improve lives around the world. We apply our research-and-development platform to human prescription and consumer products as well as to animal health products. Schering-Plough's vision is to "Earn Trust, Every Day" with the doctors, patients, customers and other stakeholders served by our colleagues around the world. Senior Auditor - Global Clinical Audits Requisition Number: 23429BR Global Clinical Audits Senior Auditor independently performs or leads all types of audits to assess quality level and compliance with applicable GCP regulations. Communicates audit findings and recommendations for corrective actions to clients on all levels and evaluates adequacy and completeness of corrective action plans. Reviews audit reports prior to issuance to clients for accuracy and consistency and provides guidance to auditors in communicating findings and recommendations. Evaluates audit report findings for identification of trends. Participates in evaluation of effectiveness of the audit program applied to specific projects. Applies advanced technical skills in compliance with Good Clinical Practices related to clinical research. Participates in development of written procedures for the unit. Participates in development and training of new audit staff. Participates in development of quality improvement strategies and tools for the client groups. MAJOR ACTIVITIES AND RESPONSIBILITIES Describe briefly the major activities of the position. Indicate the approximate percentage of time spent on each activity. 50% Independently conducts audits of SPRI sponsored clinical trials, including worldwide clinical investigator audits, clinical vendor audits, directed process audits, due diligence and other special audits and assessments as assigned. Communicates audit findings in writing to auditees, their management and other responsible personnel. Recommends corrective and preventive actions. Tracks generation of corrective action plans. Evaluates adequacy and completeness of corrective/preventive action plans. 15% Reviews audit reports prior to issuance to clients for accuracy and consistency. Provides guidance to the auditors in communicating findings and recommendations. Evaluates audit findings for an assessment of effectiveness of the quality and compliance program applied for specific projects and provides recommendations for increased effectiveness. Participates in evaluation of audit findings to identify compliance trends and system - related issues within client group projects for periodic communication to management. 10% Participates in development of process improvement strategies and tools for client groups and training on these strategies, as needed. 10% Participates in development and training of new audit staff. 10% Participates in development of written procedures and guidelines for the unit and associated training. 5% Maintains required knowledge of applicable regulations and government, industry and company GCP standards and their interpretations by participating in industry trainings, workshops and discussion groups. Serves as consultant to client groups in interpretations of regulations, standards and compliance issues, with minimal supervision. Qualifications: BA/BS in the life sciences and 8 years relevant industry experience with 5 years experience in the GCP - regulated environment or equivalent. or Advanced degree with 5 years of relevant industry experience and 4 years of experience in the GCP - regulated environment or equivalent. and Must be willing to travel approximately 20-30%. Must have a thorough understanding of GCP regulations and standards for interpretation of audit findings, the impact and implications. Computer skills and understanding are necessary. Excellent written and verbal communication skills are required. Appropriate technical skills in GCP compliance are necessary. Schering-Plough is an equal opportunity employer. M/F/D/V How to apply: Please copy and paste the following link into your browser address bar: http://appclix.postmasterlx.com/track.html?pid=402881bd1e48ea6f011e4b9cc7ca0684&source=crystallographic
Person to contact: Human Resources
Email address: fars.crmservices@fadv.com
Phone number: 999-999-9999
Job Posted: 12/19/08
Job ID Number: 1229697519
Postdoctoral Research Associate
Brookhaven National Lab
Department: BiologyLocation: Long Island, NY
URL: http://www.biology.bnl.gov/structure/fu.html
Start Date: Immediately
Description: A postdoctoral position is available immediately to study a class of metal transporter proteins (see JBC (2004) 279:12043; Science (2007) 317:1746). Potential candidates should have a recent Ph.D. in biochemistry or biophysics with extensive experience in protein crystallography and a strong interest in membrane protein structure biology. We offer competitive salary and outstanding opportunity for career development.
Please submit: CV and three references
Person to contact: Dax Fu
Email address: dax@bnl.gov
Phone number: 631-344-4208
Fax number: 631-344-3407
Job Posted: 12/16/08
Job ID Number: 1229477967
Postdoctoral Research Associate
Brookhaven National Laboratory
Department: Biology DepartmentLocation: 50 Bell Avenue, Upton, New York
URL: www.biology.bnl.gov/plantbio/liu.html
Start Date: immediately
Description: Requires a Ph.D. in Biochemistry or Structural Biology. Experience in protein engineering, analytical biochemistry and/or phenolic chemical characterization (FPLC, LC-MS, GC-MS, and NMR) is preferred. The qualified candidate will employ laboratory protein evolution, x-ray crystallography, and the related biochemical approaches to probe the structure-function relationship, and the structure- based protein evolution for the enzymes involved in lignocellulosic biosynthesis and /or the related secondary metabolisms. BNL has a state-of-the art facility for biochemistry and biophysics studies. Convenient synchrotron beamlines are available in National Synchrotron Light Source. Competitive salary (starting around $47K/year) will be commensurate with experience and qualification. Under the direction of C.-J. Liu, Biology Department (cliu@bnl.gov). The interested candidate should apply through Human resources at http://www.bnl.gov
Other details: Please go to www.bnl.gov, click on Job Opportunities and then Search Job List to apply for this position. Please apply to Job ID # 14649.
Please submit: CV, names of 3 references
Person to contact: Dr. Chang-Jun Liu
Surface mail address: cliu@bnl.gov
Job Posted: 11/21/08
Job ID Number: 1227320123
Postdoctoral Research Associate
Brookhaven National Laboratory
Department: Biology DepartmentLocation: 50 Bell Avenue, Upton, New York
URL: www.biology.bnl.gov/plantbio/liu.html
Start Date: immediately
Description: Requires a Ph.D. in Biochemistry or Structural Biology. Experience in protein engineering, analytical biochemistry and/or phenolic chemical characterization (FPLC, LC-MS, GC-MS, and NMR) is preferred. The qualified candidate will employ laboratory protein evolution, x-ray crystallography, and the related biochemical approaches to probe the structure-function relationship, and the structure- based protein evolution for the enzymes involved in lignocellulosic biosynthesis and /or the related secondary metabolisms. BNL has a state-of-the art facility for biochemistry and biophysics studies. Convenient synchrotron beamlines are available in National Synchrotron Light Source. Competitive salary (starting around $47K/year) will be commensurate with experience and qualification. Under the direction of C.-J. Liu, Biology Department (cliu@bnl.gov). The interested candidate should apply through Human resources at http://www.bnl.gov
Other details: Please go to www.bnl.gov, click on Job Opportunities and then Search Job List to apply for this position. Please apply to Job ID # 14649.
Please submit: CV, names of 3 references
Person to contact: Dr. Chang-Jun Liu
Surface mail address: cliu@bnl.gov
Job Posted: 11/21/08
Job ID Number: 1227320061
Post Doctoral, Protein Crystallography
Univeristy of Texas
Department: Chemistry and BiochemistryLocation: Austin Texas
Start Date: As soon as possible
Description: We are looking for a trained protein crystallographer. The main project is the identification of inhibitors for the influenza protein NS1. We are using high throughput and virtual screening, along with molecular modeling, to identify potential inhibitors. Several candidates have been identified. Future work will focus on improvement of inhibitors with the collaboration of a synthetic team and cell and animal testing team. Structural analysis of new inhibitors is important to the inhibitor design cycles. The structural biologists will be working with the organic synthesis group to help design efficacious inhibitors as drug leads. Applicants should have experience with X-ray data collection, reduction, and analysis, and model building and refinement. In addition, experience with protein purification, elementary molecular cloning, and kinetic assays is desirable. There are several other structural projects in the laboratory, including two other drug design projects.
Please submit: CV, 3 references
Person to contact: Jon Robertus
Surface mail address: Dept of Chem & Biochem, Uniiv of Texas, Austin TX, 78712
Email address: jrobertus@mail.utexas.edu
Phone number: 512-471-3175
Fax number: 512 471-6135
Job Posted: 11/20/08
Job ID Number: 1227197697
Post-doctoral Rsearch Associate
Jackson State University
Department: ChemistryLocation: Jackson, MS
Start Date: Immediately
Description: A Postdoctoral Research Associate position in chemistry is available at Jackson State University. The project involves the synthesis, characterization, modification of various colloidal quantum dots, including CdSe, CdS, PbSe, PbS, CdTe etc. followed by toxicity and safety tests on animal models and environmental systems The candidate is expected to work independently and conduct research in a highly interdisciplinary environment of chemist, biologist and toxicologist. The successful candidate should have a Ph.D. in chemistry, materials science or a related field. Applicants must demonstrate experience in nanomaterial synthesis and characterization relevant to quantum dots. Research experience in analytical chemistry, instrumental analysis, TEM, SEM is preferred. Interested applicants should email CV along with a brief summary of research experience and contact information for three references to Dr. Zikri Arslan. Please send applications via email at zikri.arslan@jsums.edu. The position is available immediately for one year with the possibility of extension for subsequent years.
Other details: JSU is an equal opportunity employer
Please submit: CV, description of research experince, contact information for 3 references
Person to contact: Dr. Zikri Arslan
Surface mail address: Jackson State University, Chemistry Department, PO Box 17910 Jackson, MS 39217
Email address: zikri.arslan@jsums.edu
Phone number: 601-979-2072
Fax number: 601-979-3674
Job Posted: 11/18/08
Job ID Number: 1227043035
Research Scientist (#26697)
Bristol-Myers Squibb
Department: Analytical Research & DevelopmentLocation: Lawrenceville, NJ
URL: www.bms.com/career
Start Date: ASAP
Description: Title: Research Scientist Req#: 26697 Location: Lawrenceville, NJ Type: Full Time Description: The successful candidate will work in a state of the art Solid State Chemistry laboratory housing two very bright rotating anode x ray generators each equipped with a single crystal and a powder diffractometer. As a member of a highly effective team, that provides crystallography collaboration in support of drug discovery and preclinical compound optimization, the candidate will be responsible for 1. Growing single crystals and assisting structure determination of discovery lead compounds and intermediates 2. Conducting powder diffraction experiments in support of crystallization efforts, formulation characterization, and single crystal studies 3. The alignment, calibration, and maintenance of the generators, single crystal or powder diffractometers, prompt and effective communication with vendors 4. Effective oral communication, timely written documentation, and data base entry of results. The candidate will also have the opportunity to develop cross site interactions with process chemists and pharmaceutical scientists and participate in the final form selection, salt and polymorph screening of Active Pharmaceutical Ingredients, API. Requirements:A PhD, MS with 4 years of experience or BS with 7 years of experience level background in organic chemistry, engineering, x ray diffraction data collection, processing and analysis is sought. The candidate should have hands on experience with x ray diffraction equipment and with the crystallization of organic or inorganic materials. Experience in single crystal methods, including structure solution and refinement, is highly desirable. A working knowledge of physical characterization techniques, e.g. thermal analysis, microscopy, sorption analysis for chemical or pharmaceutical bulk solids is a plus. Good organizational, written and verbal communication skills as well as a demonstrated ability to work on a team are likewise essential. If interested, we invite you to apply online to www.bms.com/career and enter the requisition number 26697. Bristol Myers Squibb is an equal opportunity employer M/F/D/V.
Job Posted: 11/13/08
Job ID Number: 1226592775
Research Scientist (#26697)
Bristol-Myers Squibb
Department: Analytical Research & DevelopmentLocation: Lawrenceville, NJ
URL: http://www.bms.com/career/data/index.html
Start Date: ASAP
Duration: Full Time
Description: Description: The successful candidate will work in a state of the art Solid State Chemistry laboratory housing two very bright rotating anode x ray generators each equippedwith a single crystal and a powder diffractometer. As a member of a highly effective team, that provides crystallography collaboration in support of drug discovery and preclinical compound optimization, the candidate will be responsible for 1. Growing single crystals and assisting structure determination of discovery lead compounds and intermediates 2. Conducting powder diffraction experimentsin support of crystallization efforts, formulation characterization, and singlecrystal studies 3. The alignment, calibration, and maintenance of the generators, single crystal or powder diffractometers, prompt and effective communication with vendors 4. Effective oral communication, timely written documentation, and data base entry of results. The candidate will also have the opportunity to develop cross site interactions with process chemists and pharmaceutical scientists and participate in the final form selection, salt and polymorph screening of Active Pharmaceutical Ingredients, API. Requirements: A PhD, MS with 4 years of experience or BS with 7 years of experience levelbackground in organic chemistry, engineering, x ray diffraction data collection, processing and analysis is sought. The candidate should have hands on experience with x ray diffraction equipment and with the crystallization of organic or inorganic materials. Experience in single crystal methods, including structure solution and refinement, is highly desirable. A working knowledge of physical characterization techniques, e.g. thermal analysis, microscopy, sorption analysis for chemical or pharmaceutical bulk solids is a plus. Good organizational, written and verbal communication skills as well as a demonstrated ability to work on a team are likewise essential.
Other details: To be considered for the position, please also apply directly to the position on our website
Please submit:
Person to contact: George Peterson
Email address: George.Peterson@bms.com
Job Posted: 11/13/08
Job ID Number: 1226590800
Research Scientist (#26697)
Bristol-Myers Squibb
Department: Analytical Research & DevelopmentLocation: Lawrenceville, NJ
URL: http://www.bms.com/career/data/index.html
Start Date: ASAP
Duration: Full Time
Description: Description: The successful candidate will work in a state of the art Solid State Chemistry laboratory housing two very bright rotating anode x ray generators each equippedwith a single crystal and a powder diffractometer. As a member of a highly effective team, that provides crystallography collaboration in support of drug discovery and preclinical compound optimization, the candidate will be responsible for 1. Growing single crystals and assisting structure determination of discovery lead compounds and intermediates 2. Conducting powder diffraction experimentsin support of crystallization efforts, formulation characterization, and singlecrystal studies 3. The alignment, calibration, and maintenance of the generators, single crystal or powder diffractometers, prompt and effective communication with vendors 4. Effective oral communication, timely written documentation, and data base entry of results. The candidate will also have the opportunity to develop cross site interactions with process chemists and pharmaceutical scientists and participate in the final form selection, salt and polymorph screening of Active Pharmaceutical Ingredients, API. Requirements: A PhD, MS with 4 years of experience or BS with 7 years of experience levelbackground in organic chemistry, engineering, x ray diffraction data collection, processing and analysis is sought. The candidate should have hands on experience with x ray diffraction equipment and with the crystallization of organic or inorganic materials. Experience in single crystal methods, including structure solution and refinement, is highly desirable. A working knowledge of physical characterization techniques, e.g. thermal analysis, microscopy, sorption analysis for chemical or pharmaceutical bulk solids is a plus. Good organizational, written and verbal communication skills as well as a demonstrated ability to work on a team are likewise essential.
Other details: To be considered for the position, please also apply directly to the position on our website
Please submit:
Person to contact: George Peterson
Email address: George.Peterson@bms.com
Job Posted: 11/13/08
Job ID Number: 1226590776
postdoctoral research associate
Jacskon State University
Department: Department of ChemistryLocation: Jackson, MS
URL: chem.jsums.edu/gao/
Start Date: immediately
Description: Applications are being accepted for a postdoctoral research associate working on the investigation of photoactivity from bio-molecules, developments of nano-sensitizers for singlet oxygen production, and photocatalysis. Candidates with strong background in photochemistry and photosensitization are encouraged to apply. Experiences in time-resolved laser, steady-state photolysis and NMR operation would be a plus. Please send your CV with the contact information of three references to Dr. Ruomei Gao at rgao@chem.jsums.edu.
Please submit: CV and contact information of 3 references
Person to contact: Dr. Ruomei Gao
Email address: rgao@chem.jsums.edu
Job Posted: 10/26/08
Job ID Number: 1225045953
Research Associate
Cornell University
Department: Macromolecular Diffracton Facility of Cornell High Energy Synchrotron Source (MacCHESS)Location: Ithaca, NY
Description: The Macromolecular Diffraction Facility of the Cornell High-Energy Synchrotron Source (MacCHESS) is seeking to fill a staff scientist position. Applicants should have a Ph.D. degree in a relevant area of science, as well as relevant postdoctoral experience. Those with experience in x-ray solution scattering on biological systems (SAXS and WAXS), macromolecular crystallographic phasing methods, or high-pressure protein crystallography are encouraged to apply. Of special interest are applicants who can take structural biology into the future with the coherent, high-spectral brilliance, time-resolved x-rays expected from next-generation x-ray sources such as Cornell's Energy Recovery Linac (ERL) Located on an ivy-league university campus in picturesque upstate New York, the Cornell High-Energy Synchrotron Source (CHESS) serves a world-wide user base of structural biologists, chemists, physicists, and engineers. MacCHESS is an NIH-supported National Resource providing support for structural biology at CHESS. Staff scientists are expected to initiate and carry out innovative research leading to advances in the application of X-radiation to key challenges in structural biology. In addition, scientists provide support to visiting research groups, collaborate with leading researchers at other institutions, and disseminate information to the scientific community. MacCHESS is a heavily team-oriented environment. Good communication skills, including fluency in the English language, and the ability to work in a group, are necessary. Qualified candidates should send their curriculum vitae and arrange for three letters of recommendation to be sent to Kathy Dedrick (kd73@cornell.edu) 200L Wilson Lab, Ithaca, NY 14853 Deadline for application is November 1, 2008. Starting date is negotiable. Cornell is an equal opportunity employer.
Please submit: cv, 3 references
Person to contact: Kathy Dedrick
Surface mail address: Cornell University, Wilson Lab, Ithaca, NY 14853
Email address: kd73@cornell.edu
Phone number: 607-255-0920
Fax number: 607-255-8062
Job Posted: 09/25/08
Job ID Number: 1222372657
Senior Research Biologist/Research Fellow
Merck & Co., Inc.
Location: West Point, PAURL: www.ecentralmetrics.com/url/?u=548357792-268
Description: Merck & Co. Inc., established in 1891, is a global research-driven pharmaceutical company dedicated to putting patients first. Join us and experience our culture first-hand – one of strong ethics & integrity, diversified experiences and a resounding passion for improving human health. As part of our global team, you’ll have the opportunity to collaborate with talented and dedicated colleagues while developing and expanding your career. X-Ray Crystallographer This exciting position within Merck Global Structural Biology at West Point, PA will support drug lead discovery and optimization through the determination of X-ray structures of proteins. The successful candidate will perform crystallization, crystal optimization, and structure determination of protein-ligand complexes and will work in collaboration with medicinal and computational chemists. The successful candidate will also work closely with molecular biologists and protein biochemists in a center with automated cloning, expression and crystallization technologies. Collaborative and productive interactions with other members of the cross-functional department is a must. The position involves active interaction with the internal and external scientific community to continually improve scientific understanding, including presentations at national or international meetings. Required 1. PhD degree with at least 3 years’ postdoctoral training in protein crystallography (Senior Research Biochemist) or Ph.D. degree with postdoctoral training and at least 3-6 years of industry experience in protein crystallography (Research Fellow) are required. 2. Excellent communication (written, presentation and verbal), collaboration and scientific skills are required. 3. Ability to work effectively within timelines is required. 4. Experience with project management and a demonstrated ability to manage a portfolio of projects is a plus at the Research Fellow level. 5. Experience with molecular biology and protein biochemistry is preferred. 6. Experience in the application of biophysical characterization methods (e.g., protein NMR, Biacore, Thermoflor) or functional properties (e.g., enzyme kinetics) is a plus. 7. Previous industrial experience is a plus. 8. Ability to prepare peer-reviewed publications. 9. Demonstrated potential to develop project management skills and identify/develop new areas of scientific expertise in protein crystallography. Education Requirement - PhD degree with at least 3 years’ postdoctoral training in protein crystallography (Senior Research Biochemist) or Ph.D. degree with postdoctoral training and at least 3-6 years of industry experience in protein crystallography (Research Fellow) are required. Multiple positions are available Consistently cited as a great place to work, we discover, develop, manufacture and market a wide range of vaccines and medicines to address unmet medical needs. Each of our employees is joined by an extraordinary sense of purpose — bringing Merck’s finest achievements to people around the world. We offer an excellent salary and an industry-ranked benefits program, including tuition reimbursement, work-life balance initiatives and developmental programs at all levels. Merck’s retirement package includes a pension plan and one of the best 401(k) plans in the nation. To be considered for this position, please visit our career site at www.ecentralmetrics.com/url/?u=548357792-268 to create a profile and submit your resume for requisition # BIO001876. Merck is an equal opportunity employer, M/F/D/V — proudly embracing diversity in all of its manifestations. Our work is someone’s hope. Join us. Where patients come first — Merck Search Firm Representatives Please Read Carefully: Merck is not accepting unsolicited assistance from search firms for this employment opportunity. Please, no phone calls or emails. All resumes submitted by search firms to any employee at Merck via-email, the Internet or in any form and/or method without a valid written search agreement in place for this position will be deemed the sole property of Merck. No fee will be paid in the event the candidate is hired by Merck as a result of the referral or through other means.
Job Posted: 09/24/08
Job ID Number: 1222271815
Postdoctoral Associate
Fox Chase Cancer Center
Department: Basic ScienceLocation: Philadelphia
URL: www.fccc.edu/research/pid/bu/
Start Date: Sept, 2008
Description: A postdoctoral position is available to work to study protein structure and function. We study how protein-protein interactions regulate the macromolecular assembly and intracellular trafficking of the cystic fibrosis transmembrane conductance regulator. We also use X-ray and neutron scattering to study protein structure and dynamics. The position requires a Ph. D. degree in structural biology, or membrane protein biochemistry and biophysics. Highly motivated candidates who can work independently are encouraged to apply.
Please submit: CV and 3 references
Person to contact: Zimei Bu
Email address: zimei.bu@fccc.edu
Job Posted: 09/05/08
Job ID Number: 1220604291
PostDoctoral research associate
Hauptman Woodward Instiutute
Department: Structural BiologyLocation: Buffalo, NY
URL: www.hwi.buffalo.edu
Start Date: 2009
Duration: 2=3 years
Description: biophysics, biochemistry
Please submit: CV, Past accomplishments and future plan, 3 references
Person to contact: Chaudhuri
Email address: bchaudhuri@hwi.buffalo.edu
Phone number: 7168988681
Job Posted: 08/28/08
Job ID Number: 1219959902
DBA / Programmer
i-SAFE
Department: Information TechnologyLocation: Carlsbad, CA
URL: www.isafe.org
Start Date: 9/01/2008
Description: Job Description / Summary: DBA will create and maintain SQL databases and application servers for business data analysis requirements. Desi gn and coding of backend applications that interact with in-house custom CRM application (Goldmine) in a MS-SQL environment. Write SQL queries and Stored Procedures to run reports off of information collected in Goldmine. Develop applications required by the program projects and defines functional dependencies. Key Responsibilities (work to be accomplished): • Scripting of stored procedures, data import and export utilities, and batch scripts in a development and production team setting. • Troubleshoot functional and performance issues with existing database objects. Improve performance, scalability and stability of databases. • Works in conjunction with other IT development and business groups to understand functionality, scalability, performance, security, and integration requirements from the database perspective, and translates these requirements into functional, scalable and reusable components for our application development framework. • Database Management, MS SQL Server, SQL Programming, Database Security. • Experience with SQL DTS and database Replication services. • Report on and analyze effectiveness of website and optimize website and architecture. • Self-starter with ability to work independently and proactively • Must be extremely detail-oriented and possess excellent verbal and written communication skills • MCDBA certification is a plus • Ability to manage multiple priorities in a fast-paced environment Requirements / Guidelines: Ability to determine computer problems and to coordinate hardware and/or software solutions. Ability to write technical instructions in the use of programs and/or program modifications. Ability to investigate and analyze information and to draw conclusions. Ability to communicate with and interpret the operational requirements of end users. Knowledge of customer service standards and procedures. Ability to process computer data and to format and generate reports. Knowledge of current technological developments/trends in area of expertise. Knowledge of established programming procedures and programming languages. Knowledge of computer flow charts and of programming logic and codes. Ability to implement and troubleshoot programming changes and modifications. Scope / Territory: This is a headquarters level position (i.e., without geographic dimensions or travel requirements) that has no contemporaries or associates – it is the only position in the corporation responsible for overseeing all Communication Systems and Information Technologies.
Please submit: CV, Resume
Person to contact: Roger DeVito
Surface mail address: rdevito@isafe.org
Email address: rdevito@isafe.org
Phone number: 760-603-7911 x11
Job Posted: 08/26/08
Job ID Number: 1219791049
DBA / Programmer
i-SAFE
Department: Information TechnologyLocation: Carlsbad, CA
URL: www.isafe.org
Start Date: 9/01/2008
Description: Job Description / Summary: DBA will create and maintain SQL databases and application servers for business data analysis requirements. Desi gn and coding of backend applications that interact with in-house custom CRM application (Goldmine) in a MS-SQL environment. Write SQL queries and Stored Procedures to run reports off of information collected in Goldmine. Develop applications required by the program projects and defines functional dependencies. Key Responsibilities (work to be accomplished): • Scripting of stored procedures, data import and export utilities, and batch scripts in a development and production team setting. • Troubleshoot functional and performance issues with existing database objects. Improve performance, scalability and stability of databases. • Works in conjunction with other IT development and business groups to understand functionality, scalability, performance, security, and integration requirements from the database perspective, and translates these requirements into functional, scalable and reusable components for our application development framework. • Database Management, MS SQL Server, SQL Programming, Database Security. • Experience with SQL DTS and database Replication services. • Report on and analyze effectiveness of website and optimize website and architecture. • Self-starter with ability to work independently and proactively • Must be extremely detail-oriented and possess excellent verbal and written communication skills • MCDBA certification is a plus • Ability to manage multiple priorities in a fast-paced environment Requirements / Guidelines: Ability to determine computer problems and to coordinate hardware and/or software solutions. Ability to write technical instructions in the use of programs and/or program modifications. Ability to investigate and analyze information and to draw conclusions. Ability to communicate with and interpret the operational requirements of end users. Knowledge of customer service standards and procedures. Ability to process computer data and to format and generate reports. Knowledge of current technological developments/trends in area of expertise. Knowledge of established programming procedures and programming languages. Knowledge of computer flow charts and of programming logic and codes. Ability to implement and troubleshoot programming changes and modifications. Scope / Territory: This is a headquarters level position (i.e., without geographic dimensions or travel requirements) that has no contemporaries or associates – it is the only position in the corporation responsible for overseeing all Communication Systems and Information Technologies.
Please submit: CV, Resume
Person to contact: Roger DeVito
Surface mail address: rdevito@isafe.org
Email address: rdevito@isafe.org
Phone number: 760-603-7911 x11
Job Posted: 08/26/08
Job ID Number: 1219791036
DBA / Programmer
i-SAFE
Department: Information TechnologyLocation: Carlsbad, CA
URL: www.isafe.org
Start Date: 9/01/2008
Description: Job Description / Summary: DBA will create and maintain SQL databases and application servers for business data analysis requirements. Desi gn and coding of backend applications that interact with in-house custom CRM application (Goldmine) in a MS-SQL environment. Write SQL queries and Stored Procedures to run reports off of information collected in Goldmine. Develop applications required by the program projects and defines functional dependencies. Key Responsibilities (work to be accomplished): • Scripting of stored procedures, data import and export utilities, and batch scripts in a development and production team setting. • Troubleshoot functional and performance issues with existing database objects. Improve performance, scalability and stability of databases. • Works in conjunction with other IT development and business groups to understand functionality, scalability, performance, security, and integration requirements from the database perspective, and translates these requirements into functional, scalable and reusable components for our application development framework. • Database Management, MS SQL Server, SQL Programming, Database Security. • Experience with SQL DTS and database Replication services. • Report on and analyze effectiveness of website and optimize website and architecture. • Self-starter with ability to work independently and proactively • Must be extremely detail-oriented and possess excellent verbal and written communication skills • MCDBA certification is a plus • Ability to manage multiple priorities in a fast-paced environment Requirements / Guidelines: Ability to determine computer problems and to coordinate hardware and/or software solutions. Ability to write technical instructions in the use of programs and/or program modifications. Ability to investigate and analyze information and to draw conclusions. Ability to communicate with and interpret the operational requirements of end users. Knowledge of customer service standards and procedures. Ability to process computer data and to format and generate reports. Knowledge of current technological developments/trends in area of expertise. Knowledge of established programming procedures and programming languages. Knowledge of computer flow charts and of programming logic and codes. Ability to implement and troubleshoot programming changes and modifications. Scope / Territory: This is a headquarters level position (i.e., without geographic dimensions or travel requirements) that has no contemporaries or associates – it is the only position in the corporation responsible for overseeing all Communication Systems and Information Technologies.
Please submit: CV, Resume
Person to contact: Roger DeVito
Surface mail address: rdevito@isafe.org
Email address: rdevito@isafe.org
Phone number: 760-603-7911 x11
Job Posted: 08/26/08
Job ID Number: 1219791021
Postdoctoral Fellow
University of Pennsylvania School of Medicine
Department: Department of PhysiologyLocation: Philadelphia
URL: http://www.med.upenn.edu/dominguez/
Start Date: immediately
Duration: Two-year renewable contract
Description: A postdoctoral position is available immediately to study the structure and function of actin cytoskeleton dynamics. The actin cytoskeleton is a vast area, involving actin-binding proteins, signaling proteins, cytoskeleton scaffolding and membrane binding proteins. Most of the projects deal with protein complexes and involve large-scale protein expression and purification, biochemical and biophysical characterization and protein crystallography. Potential candidates should have a recent Ph.D. in biochemistry or biophysics. We offer competitive salary and benefits and outstanding opportunities for career development.
Please submit: CV, 3 references
Person to contact: Roberto Dominguez
Surface mail address: A507 Richards Bldg, 3700 Hamilton Walk, Philadelphia, PA 19104-6085
Email address: droberto@mail.med.upenn.edu
Phone number: 215-573-4559
Fax number: 215-573-5851
Job Posted: 08/25/08
Job ID Number: 1219689282
Post Doctoral, Protein Crystallography
University of Texas
Department: Chemistry and BiochemistryLocation: Austin Texas
URL: www.icmb.utexas.edu/directory/details.asp?id=1773
Start Date: immediate
Description: We are looking for a trained protein crystallographer. The main project is the identification of inhibitors for the A chain of the cytotoxin called ricin. The project is reasonably well advanced with several modest inhibitors now known from virtual screening and high throughput screening of diversity libraries. Future work will focus on improvement of inhibitors with the collaboration of a synthetic team and cell and animal testing team. Structural analysis of new inhibitors is important to the inhibitor design cycles. The structural biologists will be working with the organic synthesis group to help design efficacious inhibitors as drug leads. Applicants should have experience with X-ray data collection, reduction, and analysis, and model building and refinement. In addition, experience with protein purification, elementary molecular cloning, and kinetic assays is desirable. There are several other structural projects in the laboratory, including two other drug design project. In additon, we are engaged in an experimental Freshman research project, dealing with in silico virtual screening, which may offer teaching opportunities to candidates who are so inclined.
Please submit: CV, 3 references
Person to contact: Jon Robertus
Surface mail address: Dept of Chem & Biochem, Uniiv of Texas, Austin TX, 78712
Email address: jrobertus@mail.utexas.edu
Phone number: 512-471-3175
Fax number: 512 471-6135
Job Posted: 08/07/08
Job ID Number: 1218134601
Research Associate/Sr. Research Associate
Locus Pharmaceuticals, inc.
Department: Structural BiologyLocation: Blue Bell, PA
URL: www.locuspharma.com
Start Date: ASAP
Description: Locus Pharmaceuticals, Inc. is a world leader in fragment-based, computational drug design. We have combined highly integrated chemistry, crystallography and biology capabilities to create a unique drug design and development platform for oral drug therapies in areas of unmet need. All of our development programs emanate from our proprietary computational technology and have been directed primarily in cancer and inflammation. The most advanced program is in Phase I human testing for cancer and two additional programs are in late stage preclinical development. Locus Pharmaceuticals has an immediate opening for a highly motivated and enthusiastic Research Associate to join Structural Biology Group. Duties: The successful candidate will be primarily responsible for purification, characterization, and crystallization of proteins for structural determination. The work includes development of novel purification protocols as well as optimization of existing protein purification strategies and crystallizing proteins in the presence or absence of small molecule ligands. The qualified individual should be able to work independently but collaboratively with a varied group of scientists. Skills: · Expertise in the area of protein purification and characterization with experience in a crystallography highly preferred. · Experience with and understanding of ion exchange, gel filtration, HIC, affinity and reverse phase chromatography required. · Broad experience with a variety of biochemical methods for protein characterization (protein quantitation, protein modification strategies, cross linking, limited proteolysis) is desirable. · Excellent instrument skills including the use of AKTA systems required. The successful candidate will be highly organized, able to work independently when necessary, have the ability to effectively collaborate within multidisciplinary teams, and possess good communication skills. Education: BS or MS in biochemistry, chemistry or related discipline
Please submit: CV
Person to contact: Susan Little - Sr. Director, HR
Email address: slittle@locuspharma.com
Job Posted: 07/31/08
Job ID Number: 1217525960
Post-doctoral Scientist
Purdue University
Department: Biological SciencesLocation: West Lafayette, Indiana, USA
Start Date: As soon as possible
Duration: two to five years
Description: A post-doctoral position is available in a virus structure laboratory. Applicants should have experience in computer program development or adaptation for crystallography or electron microscopy. Please e-mail applications to Michael Rossmann, mr@purdue.edu (dept of Biological Sciences, Purdue University, West Lafayette, IN 47907, USA).
Other details: NIH salary scale. Purdue employee benefits.
Please submit: Cv, 3 references, application letter
Person to contact: Michael G. Rossmann
Surface mail address: 915 W. State Street, Purdue University, West Lafayette, IN 47907, USA
Email address: mr@purdue.edu
Phone number: 765-494-4911
Fax number: 765-496-1189
Job Posted: 07/26/08
Job ID Number: 1217078680
Post-doctoral Scientist
Purdue University
Department: Biological SciencesLocation: West Lafayette, Indiana, 47907, USA
URL: http://bilbo.bio.purdue.edu/~viruswww/Rossmann_home/index.shtml
Start Date: As soon as possible
Duration: two to five years
Description: A post-doctoral position is available in a virus structure laboratory. Applicants should have experience in computer program development or adaptation for crystallography or electron microscopy. Please e-mail applications to Michael Rossmann, mr@purdue.edu (dept of Biological Sciences, Purdue University, West Lafayette, IN 47907, USA).
Person to contact: Michael Rossmann
Surface mail address: Dept. of Biological Sciences,
Job Posted: 07/26/08
Job ID Number: 1217078220
NIH funded Postdoctoral Fellowship
NIH main campus
Location: Bethesda MarylandURL: snb.nichd.nih.gov/index.htm
Start Date: fall 2008
Duration: open until filled
Description: A postdoctoral position is available to study the structure and function of neurotransmitter receptors. We are looking for a highly motivated person who would like to join a group which combines crystallographic studies with biochemical and electrophysiological experiments to understand the function of glutamate receptor ion channels, the major mediators of excitatory synaptic transmission in the brain. A major component of the work involves protein expression and crystallization trials. Preference will be give to candidates with strong skills in protein purification and large scale expression in insect cell or mamalian cell culture techniques. Experience in macromolecular crystallography, or cell biology highly desirable. Must have excellent communication skills in English and a superb ability to work as part of a team. The research facilities at NIH are outstanding with regular access to the SER-CAT beamline at APS. Recent papers describing work from the lab include: Nat Struct Mol Biol 13:1120-7 (Recent papers describing work from the lab include: Nat Struct Mol Biol 13:1120-7 (2006); Nature 440 :456-462 (2006); Neuron 53:829-841 (2007); Neuron 58:720-735 (2008); EMBO J PMID: 18636091 (2008)
Other details: Candidates must have been awarded PhD degree no earlier that 5 years prior to start of fellowship. NIH is an Affirmative action employer. J1 visa sponsorship for non US nationals (H1 visa NOT available for this position).
Please submit: CV, names for 3 references, 1 page summary of research experience
Person to contact: Dr. M.L. Mayer
Email address: mayerm@mail.nih.gov
Job Posted: 07/23/08
Job ID Number: 1216858279
Postdoctoral Research Fellow
Children's National Medical Center
Department: Children's Research InstituteLocation: Washington, DC
URL: www.childrensnational.org/research/
Start Date: ASAP
Description: A Post-doctoral position in structural biology is available to train in structural biology of proteins of the urea cycle and arginine biosynthesis. The successful candidate will be mentored in generating and testing scientific hypotheses related to structural biology and biochemistry. He/she will works independently on projects under general guidance. Tasks will include design of study, collection and analysis of data, and reporting of results at symposia and in peer-reviewed manuscripts. Education & Training Required: Ph.D. or equivalent doctoral degree in molecular biology or related field. Major: Must have fulfilled all requirements and obtained the doctoral degree. Majors preferred: Biology, Biochemistry, Structural Biology, Molecular Biology, Cell Biology or Microbiology. Experience Required: 2-3 years of related experience. Experience may have been obtained during doctoral training. Previous supervisory experience not required. Special Knowledge, Skills, Abilities: Experience in protein biochemistry and molecular biology methods . Math proficiency and basic statistical skills. Basic UNIX skills. The following specific skills are preferred: construction of plasmids, transfection of cultured cells, gel electrophoresis, PCR analysis, protein purification, RNA and DNA purification, organelle fractionation, SDS/PAGE and western blotting.
Please submit: CV, names and contact information for 3 references
Person to contact: Dr. Dashuang Shi
Surface mail address: 111 Michigan Avenue
Email address: dshi@cnmcresearch.org
Phone number: 202-476-5817
Fax number: 202-476-6014
Job Posted: 07/16/08
Job ID Number: 1216215179
Postdoctoral Fellow - Drug Discovery & Structural Biology
Moffitt Cancer Center
Department: Drug DiscoveryLocation: Tampa, FL
URL: www.moffitt.org/careers
Start Date: Immediately
Description: Postdoctoral positions are available immediately to study the structure and function of diverse drug targets at the Moffitt Cancer Center. The successful candidates will perform experiments on various medicinally important proteins to discover novel inhibitors with potential as drugs. Qualified candidates should have a PhD or equivalent degree in Biology, Biochemistry, Chemistry or related field. Experience in protein crystallography or molecular modeling or protein chemistry is required. Additional experience in DNA recombinant technology and over-expression of proteins in bacteria, insect cells and/or yeast is a plus. Excellent verbal and written communication skills are required. The H. Lee Moffitt Comprehensive Cancer Center is a modern facility on the University of South Florida Campus that conducts research on various aspects of Cancer Biology with emphasis on translational research. It is the third largest Cancer Center in the US based on patient volume. Research environment includes state of the art modern core research facilities. Please apply online at www.moffitt.org/careers to REQ ID 2622 and send CV, cover letter, and the names and contact information of three references to Dr. Ernst Schönbrunn via email at ernst.schonbrunn@moffitt.org.
Other details: Equal Oportunity/Affirmative Action Employer.
Please submit: CV, cover letter, and contact information for three references
Person to contact: Dr. Ernst Schönbrunn
Email address: ernst.schonbrunn@moffitt.org
Job Posted: 07/11/08
Job ID Number: 1215804677
Postdoctoral Scholar
Johns Hopkins University Medical School
Department: Biophysics and Biophysical ChemistryLocation: Baltimore, Maryland
URL: biophysics.med.jhmi.edu/BIOPHYS/wade.html
Start Date: 7/01/2008
Description: Postdoctoral Position in the Department of Biophysics and Biophysical Chemistry at Johns Hopkins University in the Wade Laboratory. We use a battery of biophysical techniques to study the basis of multidrug recognition and biological switch properties of transcription regulators involved in bacterial multidrug resistance. Techniques used in the lab include steady state and time-resolved fluorescence spectroscopy, x-ray crystallography, analytical ultracentrifugation, isothermal calorimetry as well as a number of gel-based methods. Extensive experience in protein crystallography is preferred; the applicant must also be interested in pursuing techniques, which complement the structural approaches. Competitive salary and benefits.
Please submit: CV, 3 references
Person to contact: Herschel Wade
Surface mail address: 709 Huntarian, 725 N. Wolfe Street
Email address: herschel.wade@jhmi.edu
Phone number: 410 955 3077
Fax number: 410 502 6910
Job Posted: 05/29/08
Job ID Number: 1212087782
Postdoctoral Fellowship: Protein Crystallography
EMBL (European Molecular Biology Laboratory)
Location: Hamburg, GermanyURL: www.embl.org/jobs
Start Date: ASAP
Duration: 24 months
Description: We are developing new methods and technologies in macromolecular crystallization and are looking for a postdoc with expertise in the area of x-ray crystallography with an emphasis on the following topics: -Protein expression and purification -Macromolecular crystallization -Protein crystal characterization (e.g. with x-ray or MetriPol analysis) -Structural biology The projects involve the testing and design of new crystallization methods and devices and the adaptation of existing techniques to crystallization. Applicants are also encouraged to perform research in structural biology. Qualifications and experience: In addition to a PhD in a related field, applicants should also have a track record in structural biology. The successful candidate will work in a multidisciplinary environment with collaborators from industry and academia. The EMBL is an international research organization with English as a first language. Good communication and presentation skills are required. EMBL is an inclusive, equal opportunity employer offering attractive conditions and benefits appropriate to an international research organisation. Further information on the position can be obtained from Dr. Jochen Mueller Dieckmann: jochenmd@embl-hamburg.de
Please submit: To apply please email a cover letter, CV and names and contact information of three references, quoting ref. no. ACA/08/PD/08 in the subject line, to: application@embl.de
Person to contact: EMBL Personnel Section
Email address: application@embl.de
Job Posted: 05/27/08
Job ID Number: 1211899602
postdoctoral fellow
Massachusetts General Hospital/Harvard Medical School
Department: Renal UnitLocation: Boston, MA
Start Date: immediately
Description: A postdoctoral position is immediately available for a highly motivated individual with a recent Ph.D to study structure-function of integrin at Massachusetts General Hospital/Harvard Medical School. Diffractable crystals have been obtained. Experience in protein crystallography is advantageous but not absolutely required if he/she is willing to learn. Preference will be given to candidates who have a strong background in molecular biology and protein expression, especially in mammalian cells. The initial period of employment is for 2 years starting as soon as possible with renewal for two more years thereafter.
Please submit: CV and names of three references
Person to contact: Dr. Jian-Ping Xiong
Surface mail address: Renal Unit, Massachusetts General Hospital, 149 13th St., Charlestown, MA 02129
Email address: xiong@helix.mgh.harvard.edu
Job Posted: 05/20/08
Job ID Number: 1211301530
Postdoctoral Fellowship in Macromolecular Crystallography
Lawrence Berkeley Laboratory
Department: Physical BiosciencesLocation: Berkeley, California
URL: cci.lbl.gov/~paul/jobs.html
Start Date: 3/28/2008
Duration: Up to 3 years
Description: This postdoctoral position will study the structure and function of macromolecular complexes and enzymes using X-ray crystallographic methods. This position will be shared between the Center for Protein Folding Machinery (proteinfoldingcenter.org) and the Joint BioEnergy Institute (JBEI). The biological systems to be studied will include: Type-II chaperonins responsible for the refolding of unfolded proteins in archeal and mammalian cells, Glycosyl transferases responsible for the synthesis of hemicellulose in plants, and Novel glycosyl hydrolases that are able to breakdown cellulosic material for biofuels production. The candidate will have experience with using crystallographic methods to study macromolecules; robotic hardware for performing crystallization trials and imaging trays are available. Crystals will be characterized and data collected using the beamline resources of the Berkeley Center for Structural Biology at the Advanced Light Source. Essential: Primary duties and responsibilities will include using robotic hardware to perform screens for crystallization conditions. Optimization of crystallization conditions. Biophysical characterization of protein samples using standard techniques, such as dynamic light scattering. Characterization of crystals using the Berkeley Center for Structural Biology beamlines at the Advanced Light Source. Collection and analysis of diffraction data, model building and structure refinement. Extensive email and verbal interaction with other researchers. Marginal: Use of small angle X-ray scattering methods to analyze macromolecular complexes in solution. Essential: Ph.D. or equivalent in a scientific discipline, preferably structural biology, biology, or chemistry. Demonstrated experience of scientific research using crystallographic methods. Experience with crystallization methods. Solid interpersonal skills and the ability to work in a team environment are critical. Ability to communicate with a broad range of researchers. Marginal: Experience with the use of small angle scattering methods. Familiarity with robotic hardware for crystal growth. NOTE: This is a one year Term appointment with the possibility of renewal under the same terms and conditions, contingent upon continued funding and availability of work. Lawrence Berkeley National Laboratory is a world leader in science and engineering research, with 11 Nobel Prize recipients over the past 75 years, and 59 present members of the National Academy of Sciences. LBNL conducts unclassified research across a wide range of scientific disciplines and hosts four national user facilities. AA/ EEO employer committed to the development of a safe and diverse workforce. Learn more at http://www.lbl.gov. For more information about the Center for Protein Folding Machinery visit: http://proteinfoldingcenter.org/ and the Joint BioEnergy Institute visit: http://www.jbei.org/. For more information about the Berkeley Center for Structural Biology visit: http://bcsb.lbl.gov/ To apply: visit http://cjo.lbl.gov/ and search for the job number 21615. Please see http://cjo.lbl.gov/app_instr.html for details of how to apply.
Job Posted: 04/13/08
Job ID Number: 1208144770
postdoctoral position
University of Illinois at Chicago
Department: BIological SciencesLocation: Chicago, Illinois, USA
Start Date: available immediately
Description: A postdoctoral position is available in the Jeffery lab in the Dept. of Biological Sciences at the University of Illinois at Chicago. The successful candidate will join an ongoing project to determining the structure and mechanism of function of multidrug resistance transmembrane transporters and other transmembrane proteins. Experience in purification, solubilization, crystallization, and X-ray crystal structure determination of membrane proteins is preferred, but candidates with significant experience in protein purification, crystallization, and/or X-ray crystal structure determination of other proteins will also be considered. Also, experience in surface plasmon resonance (SPR) or other methods to study protein-protein interactions or protein-ligand interactions is desired. UIC is the largest university in the Chicago area and is located about 30 min from the Advanced Photon Source, one of the top synchrotrons in the world. Review of applicants will begin immediately. Candidates should please send by email (cjeffery@uic.edu) a current curriculum vitae, names and contact information for three references, and a cover letter describing his or her interest in the project.
Please submit: CV, names and contact information for 3 references, letter describing candidate's interest in the lab and project
Person to contact: Prof. Connie Jeffery
Surface mail address: MC567 900 S. Ashland Ave., Chicago, IL, 60607 USA
Email address: cjeffery@uic.edu
Phone number: 312-996-3168
Fax number: 312-413-2691
Job Posted: 04/02/08
Job ID Number: 1207178630
postdoctoral position
University of Illinois at Chicago
Department: BIological SciencesLocation: Chicago, Illinois, USA
Start Date: available immediately
Description: A postdoctoral position is available in the Jeffery lab in the Dept. of Biological Sciences at the University of Illinois at Chicago. The successful candidate will join an ongoing project to determining the structure and mechanism of function of multidrug resistance transmembrane transporters and other transmembrane proteins. Experience in purification, solubilization, crystallization, and X-ray crystal structure determination of membrane proteins is preferred, but candidates with significant experience in protein purification, crystallization, and/or X-ray crystal structure determination of other proteins will also be considered. Also, experience in surface plasmon resonance (SPR) or other methods to study protein-protein interactions or protein-ligand interactions is desired. UIC is the largest university in the Chicago area and is located about 30min from the Advanced Photon Source, one of the top synchrotrons in the world. Review of applicants will begin immediately. Candidates should please send by email (cjeffery@uic.edu) a current curriculum vitae, names and contact information for three references, and a cover letter describing his or her interest in the project.
Person to contact: Prof. Connie Jeffery
Surface mail address: MC567 900 S. Ashland Ave., Chicago, IL, 60607 USA
Job Posted: 04/02/08
Job ID Number: 1207177732
Postdoctoral Research Fellow
Case Western Reserve University
Department: PharmacologyLocation: Cleveland, Ohio
URL: http://pharmacology.case.edu/department/faculty/primary/dealwis.html
Start Date: May 1st
Duration: 2-4 years
Description: A postdoctoral position is available for a highly motivated individual to elucidate structures of cancer targets. Preference will be given to individuals with strong macromolecular crystallography background. Experience in molecular biology is a definite asset.
Person to contact: Chris Dealwis
Surface mail address: 10900 Euclid Ave, Cleveland, Ohio 44106-4965, USA
Email address: cxd114@case.edu
Phone number: (216)368-1652
Job Posted: 03/27/08
Job ID Number: 1206629423
Postdoctoral Position - Crystallization
SGX Pharmaceuticals
Location: San Diego, CA 92121URL: http://www.sgxpharma.com
Start Date: 4-1-08
Description: Post Doctoral Position in Crystallization SGX is a biotechnology company focused on the discovery and development of innovative cancer therapeutics. We have an exciting opportunity for a Post Doctoral researcher to join the Crystallization group working on the Protein Structure Initiative. The goal of the PSI is to solve structures of proteins with novel folds as well as structures of proteins of community interest. The project continually tests new techniques for efficient production of these structures. The successful candidate will be involved in the optimization of protein crystals, the development of new crystallization techniques, and will be an active participant in the project as a source of ideas and mentorship. The candidate will have access to the expertise of the existing crystallization and project team, several crystallization robots, a comprehensive database for data mining, the SGX-CAT beamline for data collection and the remaining infrastructure of an organization dedicated to solving difficult protein structures. Candidates with an interest in bioinformatics will have an opportunity to participate in construct design and protein engineering. Candidates with experience in protein crystallography will have opportunities to solve and refine novel structures. Requirements: A PhD in Crystallography or a related field with extensive crystallization experience. Experience solving structures by SAD or MAD and familiarity with the requisite software a plus. Experience in bioinformatics, molecular biology, or purification a plus. Expectations: • Appointee must be eligible for employment in the U.S. • Appointment duration: Up to 2½ years, funded largely through the NIH Protein Structure Initiative. • Post Doctoral appointees are eligible for company health benefits.
Person to contact: careers@sgxpharma.com
Job Posted: 02/11/08
Job ID Number: 1202765291
Postdoctoral Research Fellow
University of Maryland
Department: Center for Advanced Research in BiotechnologyLocation: Rockville, Maryland
URL: www.umbi.umd.edu/mariuzza
Start Date: ASAP
Duration: 3-4 years
Description: NIH-funded postdoctoral position available immediately at the Center for Advanced Research in Biotechnology (CARB) of the University of Maryland for a protein crystallographer with recent PhD to join a multidisciplinary team investigating the structural basis for pathogen and tumor cell recognition by the human immune system. Several classes of recognition molecules are under study: antibodies, T cell receptors (TCRs), natural killer (NK) cell receptors, and receptors of the innate immune system (PGRPs, NODs, RIG-I). Projects include X-ray crystallographic studies of: 1) autoimmune and tumor-specific TCRs, 2) NK receptor–MHC complexes, 3) NOD–peptidoglycan complexes, and 4) RIG-I–RNA complexes. Experience in protein biochemistry is highly desirable. [Nature Immunol. 8, 398-408 (2007); Proc. Natl. Acad. Sci. USA 104, 8761-8766 (2007); Immunity 27, 572-584 (2007); Trends Biochem. Sci. 32, 500-508 (2007)]. Visit www.umbi.umd.edu/mariuzza. State-of-the-art X-ray facilities. Excellent opportunities for collaborative studies with molecular biologists and physical biochemists. CARB, a joint research center of the University of Maryland and the National Institute of Standards and Technology, is located in the heart of a major biotech community that includes MedImmune and Human Genome Sciences. Send CV and names of three references to: mariuzza@carb.nist.gov.
Please submit: CV and names of three references
Person to contact: Professor Roy A. Mariuzza
Surface mail address: 9600 Gudelsky Drive, Rockville, MD 20850
Email address: mariuzza@carb.nist.gov
Phone number: 240-314-6243
Fax number: 240-314-6225
Job Posted: 01/29/08
Job ID Number: 1201619066
Chemist Postdoctoral Fellow (Inorganic Nanocrystal Materials)
Lawrence Berkeley National Laboratory
Location: Berkeley, CAURL: http://jobs.lbl.gov/LBNLCareers/details.asp?jid=21435&p=1
Description: The Molecular Foundry at Berkeley Lab is a user facility for the design, synthesis, and characterization of materials with nanometer dimensions. One of five such Nanoscale Science Research Centers recently established by the U.S. Department of Energy, its charter is to pursue two primary missions: a) conduct outstanding research across the breadth of nanoscience; and b) collaborate with scientists from around the world who visit to use its state-of-the-art instruments, techniques, and expertise to further their own nanoscience research efforts. [See http://foundry.lbl.gov/] The Inorganic Nanostructures Facility within the Foundry offers a unique postdoctoral position in the field of inorganic nanocrystal materials. This collaboration involves an interdisciplinary team of chemists and materials scientists who explore novel nanocrystals and their integration into functional materials. The research focus is energy and electronic technologies applications. Participation in both nanocrystal synthesis and integration efforts can be anticipated. Key Responsibilities: • Synthesis of inorganic nanoparticles in the solution phase and materials characterization of synthesized particles • Integration of nanoparticles into films and composite materials (i.e., spin coating, dip coating, etc.) • Microscopic characterization of films and composite materials • Electrical and/or optical characterization of material properties Qualifications: • Relevant materials experience including nanocrystal synthesis, nanowire synthesis, sol-gel chemistry, or similar • Experience with x-ray diffraction (XRD), transmission electron microscopy (TEM), optical spectroscopy (absorption and fluorescence), infrared spectroscopy (FTIR) and/or thermal analysis such as thermogravimetric analysis (TGA) • Experience with characterization techniques such as atomic force microscopy (AFM) and scanning electron microscopy (SEM) • Experience with electronic device prototyping and characterization • Demonstrated critical analysis and communication skills evidenced by research publications in peer reviewed journals • Recent Ph.D. in Chemistry, Materials Science, or a related field Reference “Internet” and “American Crystallographic Association” as your source.
Other details: Berkeley Lab is an affirmative action/equal opportunity employer committed to the development of a diverse workforce. Learn more at www.lbl.gov.
Please submit: Please submit a single attachment with your CV and letter of interest.
Person to contact: Amy Pagsolingan
Email address: avpagsolingan@lbl.gov
Job Posted: 01/25/08
Job ID Number: 1201303923
Postdoctoral Researcher
Southern Research Institute
Department: Drug Development Division/Protein CrystallographyLocation: Birmingham, AL
URL: www.southernresearch.org
Start Date: Immediately
Description: Postdoctoral Researcher Immediate opportunity requiring a PhD in Protein Structural Biology or related discipline. Ph.D. candidates within 90 days of obtaining their diploma are also encouraged to apply (degree must be awarded prior to employment). Requires experience in protein structural biology, including 1) protein purification and crystallization, 2) data collection and processing, 3) structure determination and model refinement. Experience in molecular biology, UNIX system managing, or molecular modeling is a plus. The successful candidate will perform research projects involving protein purification, crystallization and structure determination by X-ray protein crystallography. Please apply for Position #sr-02014 at www.southernresearch.org. – AA/EOE
Other details: AA/EOE Employer
Person to contact: Apply online for Position #sr-02014
Job Posted: 01/23/08
Job ID Number: 1201115246
Postdoctoral Researcher
Purdue University
Department: Biolocial SciencesLocation: West Lafayette, IN
URL: chen.bio.purdue.edu
Start Date: immediately
Description: Postdoctoral positions in Structural Biology are available immediately in the Chen laboratory at Purdue University. As part of the Markey Center for Structural Biology, the Chen lab integrates X-ray crystallography and biochemical methods to study the mechanism of active transport (See Nature, 450: 515-521; PNAS,102:17969-17974; and Mol. Cell, 12:651-661). For more information please visit our website at http://chen.bio.purdue.edu. Successful candidates should have (or expect) a recent doctoral degree with demonstrated experience in macromolecular crystallography and protein biochemistry.
Please submit: CV and names of three referees
Person to contact: Jue Chen
Surface mail address: 915 W. State Street, West Lafayette, IN 47907
Email address: chenjue@purdue.edu
Phone number: 765-496-3113
Fax number: 765-496-1189
Job Posted: 01/10/08
Job ID Number: 1199986624
POSTDOCTORAL RESEARCH ASSOCIATE
Brookhaven National Laboratory
Department: BiologyLocation: Upton, NY, U.S.A.
Start Date: 1st quater 2008
Duration: Two years
Description: This new project is under the direction of A. M. Orville, and is also associated with the PXRR group (www.px.nsls.bnl.gov) at Brookhaven National Laboratory (BNL). The PXRR group conducts research, technology development, operations, and training at six beamlines (X8, X12b, X12c, X25, X26c, X29) at the National Synchrotron Light Source (NSLS). A long-term goal for the PXRR group is to create a resource for macromolecular crystallography at NSLS-II, the new synchrotron light source that is being created at BNL during the next five to seven years. Microcrystals only a few microns along an edge are often easy to obtain; but, are typically of no use for traditional diffraction studies. In contrast, the brightness and focused beam anticipated at NSLS-II provides an ideal opportunity to use microcrystals for diffraction studies. A major barrier that remains to be overcome is how to manipulate microcrystals for structure determination. Part of the research strategy will be to use a large number of randomly oriented microcrystals, from each of which only a small fraction of the whole dataset is collected, in order to build-up the complete dataset. Full expression of these methods may approach the physical limits of crystal diffraction and will clearly help motivate the optimum performance of NSLS-II. Consequently, we will develop novel microcrystallography methods at the NSLS and look forward to utilizing the outstanding characteristics of NSLS-II facility. The position requires a Ph.D. in biochemistry, structural biology, chemistry, or physics. Experience in macromolecular crystallography and/or synchrotron x-ray sources is desired. The prospective candidate must be able to interact with a diverse group of scientists and engineers, as well as work independently. Send CV and contact information for four mentors or referees to felicia@bnl.gov referring to Position No. FH4835.
Other details: referring to Position No. FH4835
Please submit: CV and contact info to request 4 letters of reference
Person to contact: Felicia Hartsough, FH4835
Surface mail address: Human Resources and Occupational Medicine Division, Brookhaven Nationial Lab, Upton, NY 11973
Email address: felicia@bnl.gov
Phone number: 631-344-2213
Fax number: 631-344-7170
Job Posted: 01/10/08
Job ID Number: 1199972727
Postdoctoral Associate
Harvard Medical School
Department: BCMP in collaboration with Children's Hospital; Center for Molecular and Cellular DynamicsLocation: The Hub (a.k.a. Boston, USA)
URL: www.employment.harvard.edu
Start Date: immediately
Description: A postdoctoral position is available for a highly motivated individual to study proteins from the microRNA processing pathway. Preference will be given to candidates who have a strong background in molecular biology as well as in protein and RNA biochemistry. Experience with crystallography will be advantageous and although it is not required you must be willing to learn. Please submit application materials electronically in the pdf format.
Please submit: CV, 3 references, date of availability
Person to contact: Piotr Sliz, Assistant Professor of Pediatrics
Surface mail address: 250 Longwood Ave, Rm SGM-130
Email address: sliz@crystal.harvard.edu
Phone number: 617-432-5608, ext 70
Fax number: 617-432-5600
Job Posted: 01/07/08
Job ID Number: 1199768331
Postdoctoral Research Associate
Yale University School of Medicine
Department: PharmacologyLocation: New Haven, CT
URL: info.med.yale.edu/pharm/faculty/index.php?bioID=9
Start Date: Immediately
Duration: 3-4 years
Description: A postdoctoral position is available for an NIH-sponsored study of Alzheimer's amyloid precursor protein (APP) and its disease-causing fragment. Although we use x-ray crystallography as the primary experimental tool, this project also involves monoclonal antibodies, binding studies, and extensive modeling and mutagenesis. Therefore, we prefer applicants who have substantial training in molecular biology, biochemistry and biophysics.
Please submit: c.v. and names of 3 references
Person to contact: Ya Ha, Associate Professor of Pharmacology
Surface mail address: 333 Cedar Street, New Haven, CT 06520
Email address: ya.ha@yale.edu
Phone number: 203-785-7530
Fax number: 203-785-7670
Job Posted: 01/03/08
Job ID Number: 1199377094
Last posting: 02/03/10
Problems? Send mail to aca@sdsc.edu.