Post-Doctoral Positions Available
Postdoctoral Fellow, University of Toronto, Toronto, Canada [10/08/08]
Research Associate, Cornell University, Ithaca, NY [09/25/08]
Post-Doctoral Position, Indiana University School of Medicine, Indianapolis [09/24/08]
Senior Research Biologist/Research Fellow, Merck & Co., Inc. , West Point, PA [09/24/08]
Postdoctoral Associate, Fox Chase Cancer Center, Philadelphia [09/05/08]
PostDoctoral research associate, Hauptman Woodward Instiutute, Buffalo, NY [08/28/08]
Postdoctoral Fellow, Wadsworth Center, New York State Department of Health, Albany, New York [08/27/08]
DBA / Programmer, i-SAFE, Carlsbad, CA [08/26/08]
DBA / Programmer, i-SAFE, Carlsbad, CA [08/26/08]
DBA / Programmer, i-SAFE, Carlsbad, CA [08/26/08]
Postdoctoral Fellow, University of Pennsylvania School of Medicine, Philadelphia [08/25/08]
Post Doctoral, Protein Crystallography, University of Texas, Austin Texas [08/07/08]
Research Associate/Sr. Research Associate, Locus Pharmaceuticals, inc., Blue Bell, PA [07/31/08]
Post-doctoral Scientist, Purdue University, West Lafayette, Indiana, USA [07/26/08]
Post-doctoral Scientist, Purdue University, West Lafayette, Indiana, 47907, USA [07/26/08]
NIH funded Postdoctoral Fellowship, NIH main campus, Bethesda Maryland [07/23/08]
Postdoctoral Research Fellow, Children's National Medical Center, Washington, DC [07/16/08]
Postdoctoral Fellow - Drug Discovery & Structural Biology, Moffitt Cancer Center, Tampa, FL [07/11/08]
Postdoctoral Research Associate, Brookhaven National Lab, Long Island, NY [06/27/08]
Postdoctoral Scholar, Johns Hopkins University Medical School, Baltimore, Maryland [05/29/08]
Postdoctoral Fellowship: Protein Crystallography, EMBL (European Molecular Biology Laboratory), Hamburg, Germany [05/27/08]
postdoctoral fellow, Massachusetts General Hospital/Harvard Medical School, Boston, MA [05/20/08]
Postdoctoral Fellowship in Macromolecular Crystallography, Lawrence Berkeley Laboratory, Berkeley, California [04/13/08]
postdoctoral position, University of Illinois at Chicago, Chicago, Illinois, USA [04/02/08]
postdoctoral position, University of Illinois at Chicago, Chicago, Illinois, USA [04/02/08]
Postdoctoral Research Fellow, Case Western Reserve University, Cleveland, Ohio [03/27/08]
Postdoctoral Fellow, UCSD, La Jolla/San Diego [03/24/08]
Postdoctoral Position - Crystallization, SGX Pharmaceuticals, San Diego, CA 92121 [02/11/08]
Postdoctoral Research Fellow, University of Maryland, Rockville, Maryland [01/29/08]
Chemist Postdoctoral Fellow (Inorganic Nanocrystal Materials), Lawrence Berkeley National Laboratory, Berkeley, CA [01/25/08]
Postdoctoral Researcher, Southern Research Institute, Birmingham, AL [01/23/08]
Postdoctoral Researcher, Purdue University, West Lafayette, IN [01/10/08]
POSTDOCTORAL RESEARCH ASSOCIATE, Brookhaven National Laboratory, Upton, NY, U.S.A. [01/10/08]
Postdoctoral Associate, Harvard Medical School, The Hub (a.k.a. Boston, USA) [01/07/08]
Postdoctoral Research Associate, Yale University School of Medicine, New Haven, CT [01/03/08]
University of Toronto
Department: Structural Genomics Consortium
Location: Toronto, Canada
URL: http://www.sgc.utoronto.ca/pmwiki/pmwiki.php?n=ChromatinBiologyAndEpigenetics.HomePage
Start Date: Immediately
Duration: 3 years
Description: A Post-doctoral position in structural biology is available in the Chromatin biology and Epigenetic group at the Structural Genomics Consortium, University of Toronto. My lab aims to characterize chromatin proteins involved in histone code "reading" and "writing" by X-ray crystallography in combination with other biochemical and biophysical techniques. Applicants should have a Ph.D. in structural biology, biochemistry, biophysics, chemistry, or a related field with 0-5 years postdoctoral research experience. Interested candidates are invited to send their CV with 3 references to:jr.min@utoronto.ca.
Person to contact: Jinrong Min
Phone number: 416-9463868
Job Posted: 10/08/08
Job ID Number: 1223522706
Cornell University
Department: Macromolecular Diffracton Facility of Cornell High Energy Synchrotron Source (MacCHESS)
Location: Ithaca, NY
Description: The Macromolecular Diffraction Facility of the Cornell High-Energy Synchrotron Source (MacCHESS) is seeking to fill a staff scientist position. Applicants should have a Ph.D. degree in a relevant area of science, as well as relevant postdoctoral experience. Those with experience in x-ray solution scattering on biological systems (SAXS and WAXS), macromolecular crystallographic phasing methods, or high-pressure protein crystallography are encouraged to apply. Of special interest are applicants who can take structural biology into the future with the coherent, high-spectral brilliance, time-resolved x-rays expected from next-generation x-ray sources such as Cornell's Energy Recovery Linac (ERL)
Located on an ivy-league university campus in picturesque upstate New York, the Cornell High-Energy Synchrotron Source (CHESS) serves a world-wide user base of structural biologists, chemists, physicists, and engineers. MacCHESS is an NIH-supported National Resource providing support for structural biology at CHESS. Staff scientists are expected to initiate and carry out innovative research leading to advances in the application of X-radiation to key challenges in structural biology. In addition, scientists provide support to visiting research groups, collaborate with leading researchers at other institutions, and disseminate information to the scientific community. MacCHESS is a heavily team-oriented environment. Good communication skills, including fluency in the English language, and the ability to work in a group, are necessary.
Qualified candidates should send their curriculum vitae and arrange for three letters of recommendation to be sent to Kathy Dedrick (kd73@cornell.edu) 200L Wilson Lab, Ithaca, NY 14853
Deadline for application is November 1, 2008. Starting date is negotiable. Cornell is an equal opportunity employer.
Please submit: cv, 3 references
Person to contact: Kathy Dedrick
Surface mail address: Cornell University, Wilson Lab, Ithaca, NY 14853
Email address: kd73@cornell.edu
Phone number: 607-255-0920
Fax number: 607-255-8062
Job Posted: 09/25/08
Job ID Number: 1222372657
Indiana University School of Medicine
Department: Biochemistry and Molecular Biology
Location: Indianapolis
URL: www.biochemistry.iu.edu
Start Date: October 15, 2008
Description: A post-doctoral fellow position is available in the Department of Biochemistry and Molecular Biology for individuals with experience in protein structure/function analysis and protein crystallography. The research project will entail the development of prokaryotic and eukaryotic protein expression systems, crystallizations and protein structure determination. Additional work will involve the testing of functional predictions based on the structural analysis using enzymological tools, such as steady-state kinetics, binding studies and possible pre-steady state characterization of substrate binding. Experience with linux computing environments is also desirable. A Ph.D. in Biochemistry, Biophysics, Chemistry or similar background is required. Applicants should send their CV and the names of three references to Dr. Thomas Hurley, Department of Biochemistry and Molecular Biology, 635 Barnhill Drive, Indianapolis, IN, 46202-5122 (thurley@iupui.edu).
Person to contact: Thomas Hurley
Surface mail address: 635 Barnhill Drive, Indianapolis, IN 46202-5122
Email address: thurley@iupui.edu
Phone number: 317-278-2008
Fax number: 317-274-4686
Job Posted: 09/24/08
Job ID Number: 1222284361
Merck & Co., Inc.
Location: West Point, PA
URL: www.ecentralmetrics.com/url/?u=548357792-268
Description: Merck & Co. Inc., established in 1891, is a global research-driven pharmaceutical company dedicated to putting patients first.
Join us and experience our culture first-hand – one of strong ethics & integrity, diversified experiences and a resounding passion for improving human health. As part of our global team, you’ll have the opportunity to collaborate with talented and dedicated colleagues while developing and expanding your career.
X-Ray Crystallographer
This exciting position within Merck Global Structural Biology at West Point, PA will support drug lead discovery and optimization through the determination of X-ray structures of proteins. The successful candidate will perform crystallization, crystal optimization, and structure determination of protein-ligand complexes and will work in collaboration with medicinal and computational chemists. The successful candidate will also work closely with molecular biologists and protein biochemists in a center with automated cloning, expression and crystallization technologies.
Collaborative and productive interactions with other members of the cross-functional department is a must. The position involves active interaction with the internal and external scientific community to continually improve scientific understanding, including presentations at national or international meetings.
Required
1. PhD degree with at least 3 years’ postdoctoral training in protein crystallography (Senior Research Biochemist) or Ph.D. degree with postdoctoral training and at least 3-6 years of industry experience in protein crystallography (Research Fellow) are required.
2. Excellent communication (written, presentation and verbal), collaboration and scientific skills are required.
3. Ability to work effectively within timelines is required.
4. Experience with project management and a demonstrated ability to manage a portfolio of projects is a plus at the Research Fellow level.
5. Experience with molecular biology and protein biochemistry is preferred.
6. Experience in the application of biophysical characterization methods (e.g., protein NMR, Biacore, Thermoflor) or functional properties (e.g., enzyme kinetics) is a plus.
7. Previous industrial experience is a plus.
8. Ability to prepare peer-reviewed publications.
9. Demonstrated potential to develop project management skills and identify/develop new areas of scientific expertise in protein crystallography.
Education Requirement - PhD degree with at least 3 years’ postdoctoral training in protein crystallography (Senior Research Biochemist) or Ph.D. degree with postdoctoral training and at least 3-6 years of industry experience in protein crystallography (Research Fellow) are required.
Multiple positions are available
Consistently cited as a great place to work, we discover, develop, manufacture and market a wide range of vaccines and medicines to address unmet medical needs. Each of our employees is joined by an extraordinary sense of purpose — bringing Merck’s finest achievements to people around the world.
We offer an excellent salary and an industry-ranked benefits program, including tuition reimbursement, work-life balance initiatives and developmental programs at all levels. Merck’s retirement package includes a pension plan and one of the best 401(k) plans in the nation.
To be considered for this position, please visit our career site at www.ecentralmetrics.com/url/?u=548357792-268 to create a profile and submit your resume for requisition # BIO001876. Merck is an equal opportunity employer, M/F/D/V — proudly embracing diversity in all of its manifestations.
Our work is someone’s hope. Join us.
Where patients come first — Merck
Search Firm Representatives
Please Read Carefully:
Merck is not accepting unsolicited assistance from search firms for this employment opportunity. Please, no phone calls or emails. All resumes submitted by search firms to any employee at Merck via-email, the Internet or in any form and/or method without a valid written search agreement in place for this position will be deemed the sole property of Merck. No fee will be paid in the event the candidate is hired by Merck as a result of the referral or through other means.
Job Posted: 09/24/08
Job ID Number: 1222271815
Fox Chase Cancer Center
Department: Basic Science
Location: Philadelphia
URL: www.fccc.edu/research/pid/bu/
Start Date: Sept, 2008
Description: A postdoctoral position is available to work to study protein structure and function. We study how protein-protein interactions regulate the macromolecular assembly and intracellular trafficking of the cystic fibrosis transmembrane conductance regulator. We also use X-ray and neutron scattering to study protein structure and dynamics.
The position requires a Ph. D. degree in structural biology, or membrane protein biochemistry and biophysics. Highly motivated candidates who can work independently are encouraged to apply.
Please submit: CV and 3 references
Person to contact: Zimei Bu
Email address: zimei.bu@fccc.edu
Job Posted: 09/05/08
Job ID Number: 1220604291
Hauptman Woodward Instiutute
Department: Structural Biology
Location: Buffalo, NY
URL: www.hwi.buffalo.edu
Start Date: 2009
Duration: 2=3 years
Description: biophysics, biochemistry
Please submit: CV, Past accomplishments and future plan, 3 references
Person to contact: Chaudhuri
Email address: bchaudhuri@hwi.buffalo.edu
Phone number: 7168988681
Job Posted: 08/28/08
Job ID Number: 1219959902
Wadsworth Center, New York State Department of Health
Department: New York State Department of Health
Location: Albany, New York
URL: http://www.wadsworth.org/resnres/bios/lihongmin.htm
Start Date: ASAP
Description: A postdoctoral position is immediately available to study structure and function of proteins or protein complexes related to bacterial or viral infection and host response (http://www.wadsworth.org/resnres/bios/lihongmin.htm). The position is funded for 1 year through research grants from the NIH and private foundations, and may be extended dependent upon the availability of funding and satisfactory performance. The successful candidate should have a recent Ph.D. degree with highly motivation and interest in structure biology. Experiences in molecular biology and protein expression using insect cells (baculovirus, drosophila) will be advantaged. The position is at the Wadsworth Center, one of the nation's 'Best Places to Work in Academia.' (http://www.wadsworth.org). The Capitol city of Albany offers a reasonable cost-of-living and we offer competitive salary and benefits (NIH standard) and outstanding opportunities for career development.
Interested applicants should email a CV, including a list of publications, and the names of three references including the doctoral supervisor, to:
Hongmin Li, PhD
Wadsworth Center
New York State Department of Health
150 New Scotland Ave
Albany, NY 12208
Tel: 518-486-9154
Email: lih@wadsworth.org
Please submit: CV, 3 references, etc.
Person to contact: Hongmin Li
Surface mail address: lih@wadsworth.org
Email address: lih@wadsworth.org
Phone number: 518-486-9154
Job Posted: 08/27/08
Job ID Number: 1219858150
i-SAFE
Department: Information Technology
Location: Carlsbad, CA
URL: www.isafe.org
Start Date: 9/01/2008
Description: Job Description / Summary: DBA will create and maintain SQL databases and application servers for business data analysis requirements. Desi gn and coding of backend applications that interact with in-house custom CRM application (Goldmine) in a MS-SQL environment. Write SQL queries and Stored Procedures to run reports off of information collected in Goldmine. Develop applications required by the program projects and defines functional dependencies.
Key Responsibilities (work to be accomplished):
• Scripting of stored procedures, data import and export utilities, and batch scripts in a development and production team setting.
• Troubleshoot functional and performance issues with existing database objects. Improve performance, scalability and stability of databases.
• Works in conjunction with other IT development and business groups to understand functionality, scalability, performance, security, and integration requirements from the database perspective, and translates these requirements into functional, scalable and reusable components for our application development framework.
• Database Management, MS SQL Server, SQL Programming, Database Security.
• Experience with SQL DTS and database Replication services.
• Report on and analyze effectiveness of website and optimize website and architecture.
• Self-starter with ability to work independently and proactively
• Must be extremely detail-oriented and possess excellent verbal and written communication skills
• MCDBA certification is a plus
• Ability to manage multiple priorities in a fast-paced environment
Requirements / Guidelines:
Ability to determine computer problems and to coordinate hardware and/or software solutions.
Ability to write technical instructions in the use of programs and/or program modifications.
Ability to investigate and analyze information and to draw conclusions.
Ability to communicate with and interpret the operational requirements of end users.
Knowledge of customer service standards and procedures.
Ability to process computer data and to format and generate reports.
Knowledge of current technological developments/trends in area of expertise.
Knowledge of established programming procedures and programming languages.
Knowledge of computer flow charts and of programming logic and codes.
Ability to implement and troubleshoot programming changes and modifications.
Scope / Territory:
This is a headquarters level position (i.e., without geographic dimensions or travel requirements) that has no contemporaries or associates – it is the only position in the corporation responsible for overseeing all Communication Systems and Information Technologies.
Please submit: CV, Resume
Person to contact: Roger DeVito
Surface mail address: rdevito@isafe.org
Email address: rdevito@isafe.org
Phone number: 760-603-7911 x11
Job Posted: 08/26/08
Job ID Number: 1219791049
i-SAFE
Department: Information Technology
Location: Carlsbad, CA
URL: www.isafe.org
Start Date: 9/01/2008
Description: Job Description / Summary: DBA will create and maintain SQL databases and application servers for business data analysis requirements. Desi gn and coding of backend applications that interact with in-house custom CRM application (Goldmine) in a MS-SQL environment. Write SQL queries and Stored Procedures to run reports off of information collected in Goldmine. Develop applications required by the program projects and defines functional dependencies.
Key Responsibilities (work to be accomplished):
• Scripting of stored procedures, data import and export utilities, and batch scripts in a development and production team setting.
• Troubleshoot functional and performance issues with existing database objects. Improve performance, scalability and stability of databases.
• Works in conjunction with other IT development and business groups to understand functionality, scalability, performance, security, and integration requirements from the database perspective, and translates these requirements into functional, scalable and reusable components for our application development framework.
• Database Management, MS SQL Server, SQL Programming, Database Security.
• Experience with SQL DTS and database Replication services.
• Report on and analyze effectiveness of website and optimize website and architecture.
• Self-starter with ability to work independently and proactively
• Must be extremely detail-oriented and possess excellent verbal and written communication skills
• MCDBA certification is a plus
• Ability to manage multiple priorities in a fast-paced environment
Requirements / Guidelines:
Ability to determine computer problems and to coordinate hardware and/or software solutions.
Ability to write technical instructions in the use of programs and/or program modifications.
Ability to investigate and analyze information and to draw conclusions.
Ability to communicate with and interpret the operational requirements of end users.
Knowledge of customer service standards and procedures.
Ability to process computer data and to format and generate reports.
Knowledge of current technological developments/trends in area of expertise.
Knowledge of established programming procedures and programming languages.
Knowledge of computer flow charts and of programming logic and codes.
Ability to implement and troubleshoot programming changes and modifications.
Scope / Territory:
This is a headquarters level position (i.e., without geographic dimensions or travel requirements) that has no contemporaries or associates – it is the only position in the corporation responsible for overseeing all Communication Systems and Information Technologies.
Please submit: CV, Resume
Person to contact: Roger DeVito
Surface mail address: rdevito@isafe.org
Email address: rdevito@isafe.org
Phone number: 760-603-7911 x11
Job Posted: 08/26/08
Job ID Number: 1219791036
i-SAFE
Department: Information Technology
Location: Carlsbad, CA
URL: www.isafe.org
Start Date: 9/01/2008
Description: Job Description / Summary: DBA will create and maintain SQL databases and application servers for business data analysis requirements. Desi gn and coding of backend applications that interact with in-house custom CRM application (Goldmine) in a MS-SQL environment. Write SQL queries and Stored Procedures to run reports off of information collected in Goldmine. Develop applications required by the program projects and defines functional dependencies.
Key Responsibilities (work to be accomplished):
• Scripting of stored procedures, data import and export utilities, and batch scripts in a development and production team setting.
• Troubleshoot functional and performance issues with existing database objects. Improve performance, scalability and stability of databases.
• Works in conjunction with other IT development and business groups to understand functionality, scalability, performance, security, and integration requirements from the database perspective, and translates these requirements into functional, scalable and reusable components for our application development framework.
• Database Management, MS SQL Server, SQL Programming, Database Security.
• Experience with SQL DTS and database Replication services.
• Report on and analyze effectiveness of website and optimize website and architecture.
• Self-starter with ability to work independently and proactively
• Must be extremely detail-oriented and possess excellent verbal and written communication skills
• MCDBA certification is a plus
• Ability to manage multiple priorities in a fast-paced environment
Requirements / Guidelines:
Ability to determine computer problems and to coordinate hardware and/or software solutions.
Ability to write technical instructions in the use of programs and/or program modifications.
Ability to investigate and analyze information and to draw conclusions.
Ability to communicate with and interpret the operational requirements of end users.
Knowledge of customer service standards and procedures.
Ability to process computer data and to format and generate reports.
Knowledge of current technological developments/trends in area of expertise.
Knowledge of established programming procedures and programming languages.
Knowledge of computer flow charts and of programming logic and codes.
Ability to implement and troubleshoot programming changes and modifications.
Scope / Territory:
This is a headquarters level position (i.e., without geographic dimensions or travel requirements) that has no contemporaries or associates – it is the only position in the corporation responsible for overseeing all Communication Systems and Information Technologies.
Please submit: CV, Resume
Person to contact: Roger DeVito
Surface mail address: rdevito@isafe.org
Email address: rdevito@isafe.org
Phone number: 760-603-7911 x11
Job Posted: 08/26/08
Job ID Number: 1219791021
University of Pennsylvania School of Medicine
Department: Department of Physiology
Location: Philadelphia
URL: http://www.med.upenn.edu/dominguez/
Start Date: immediately
Duration: Two-year renewable contract
Description: A postdoctoral position is available immediately to study the structure and function of actin cytoskeleton dynamics. The actin cytoskeleton is a vast area, involving actin-binding proteins, signaling proteins, cytoskeleton scaffolding and membrane binding proteins. Most of the projects deal with protein complexes and involve large-scale protein expression and purification, biochemical and biophysical characterization and protein crystallography. Potential candidates should have a recent Ph.D. in biochemistry or biophysics. We offer competitive salary and benefits and outstanding opportunities for career development.
Please submit: CV, 3 references
Person to contact: Roberto Dominguez
Surface mail address: A507 Richards Bldg, 3700 Hamilton Walk, Philadelphia, PA 19104-6085
Email address: droberto@mail.med.upenn.edu
Phone number: 215-573-4559
Fax number: 215-573-5851
Job Posted: 08/25/08
Job ID Number: 1219689282
University of Texas
Department: Chemistry and Biochemistry
Location: Austin Texas
URL: www.icmb.utexas.edu/directory/details.asp?id=1773
Start Date: immediate
Description: We are looking for a trained protein crystallographer. The main project is the identification of inhibitors for the A chain of the cytotoxin called ricin. The project is reasonably well advanced with several modest inhibitors now known from virtual screening and high throughput screening of diversity libraries.
Future work will focus on improvement of inhibitors with the collaboration of a synthetic team and cell and animal testing team. Structural analysis of new inhibitors is important to the inhibitor design cycles. The structural biologists will be working with the organic synthesis group to help design efficacious inhibitors as drug leads.
Applicants should have experience with X-ray data collection, reduction, and analysis, and model building and refinement. In addition, experience with protein purification, elementary molecular cloning, and kinetic assays is desirable.
There are several other structural projects in the laboratory, including two other drug design project. In additon, we are engaged in an experimental Freshman research project, dealing with in silico virtual screening, which may offer teaching opportunities to candidates who are so inclined.
Please submit: CV, 3 references
Person to contact: Jon Robertus
Surface mail address: Dept of Chem & Biochem, Uniiv of Texas, Austin TX, 78712
Email address: jrobertus@mail.utexas.edu
Phone number: 512-471-3175
Fax number: 512 471-6135
Job Posted: 08/07/08
Job ID Number: 1218134601
Locus Pharmaceuticals, inc.
Department: Structural Biology
Location: Blue Bell, PA
URL: www.locuspharma.com
Start Date: ASAP
Description: Locus Pharmaceuticals, Inc. is a world leader in fragment-based, computational drug design. We have combined highly integrated chemistry, crystallography and biology capabilities to create a unique drug design and development platform for oral drug therapies in areas of unmet need. All of our development programs emanate from our proprietary computational technology and have been directed primarily in cancer and inflammation. The most advanced program is in Phase I human testing for cancer and two additional programs are in late stage preclinical development. Locus Pharmaceuticals has an immediate opening for a highly motivated and enthusiastic Research Associate to join Structural Biology Group. Duties: The successful candidate will be primarily responsible for purification, characterization, and crystallization of proteins for structural determination. The work includes development of novel purification protocols as well as optimization of existing protein purification strategies and crystallizing proteins in the presence or absence of small molecule ligands. The qualified individual should be able to work independently but collaboratively with a varied group of scientists. Skills: · Expertise in the area of protein purification and characterization with experience in a crystallography highly preferred. · Experience with and understanding of ion exchange, gel filtration, HIC, affinity and reverse phase chromatography required. · Broad experience with a variety of biochemical methods for protein characterization (protein quantitation, protein modification strategies, cross linking, limited proteolysis) is desirable. · Excellent instrument skills including the use of AKTA systems required. The successful candidate will be highly organized, able to work independently when necessary, have the ability to effectively collaborate within multidisciplinary teams, and possess good communication skills. Education: BS or MS in biochemistry, chemistry or related discipline
Please submit: CV
Person to contact: Susan Little - Sr. Director, HR
Email address: slittle@locuspharma.com
Job Posted: 07/31/08
Job ID Number: 1217525960
Purdue University
Department: Biological Sciences
Location: West Lafayette, Indiana, USA
Start Date: As soon as possible
Duration: two to five years
Description: A post-doctoral position is available in a virus structure laboratory. Applicants should have experience in computer program development or adaptation for crystallography or electron microscopy. Please e-mail applications to Michael Rossmann, mr@purdue.edu (dept of Biological Sciences, Purdue University, West Lafayette, IN 47907, USA).
Other details: NIH salary scale. Purdue employee benefits.
Please submit: Cv, 3 references, application letter
Person to contact: Michael G. Rossmann
Surface mail address: 915 W. State Street, Purdue University, West Lafayette, IN 47907, USA
Email address: mr@purdue.edu
Phone number: 765-494-4911
Fax number: 765-496-1189
Job Posted: 07/26/08
Job ID Number: 1217078680
Purdue University
Department: Biological Sciences
Location: West Lafayette, Indiana, 47907, USA
URL: http://bilbo.bio.purdue.edu/~viruswww/Rossmann_home/index.shtml
Start Date: As soon as possible
Duration: two to five years
Description: A post-doctoral position is available in a virus structure laboratory. Applicants should have experience in computer program development or adaptation for crystallography or electron microscopy. Please e-mail applications to Michael Rossmann, mr@purdue.edu (dept of Biological Sciences, Purdue University, West Lafayette, IN 47907, USA).
Person to contact: Michael Rossmann
Surface mail address: Dept. of Biological Sciences,
Job Posted: 07/26/08
Job ID Number: 1217078220
NIH main campus
Location: Bethesda Maryland
URL: snb.nichd.nih.gov/index.htm
Start Date: fall 2008
Duration: open until filled
Description: A postdoctoral position is available to study the structure and function of neurotransmitter receptors. We are looking for a highly motivated person who would like to join a group which combines crystallographic studies with biochemical and electrophysiological experiments to understand the function of glutamate receptor ion channels, the major mediators of excitatory synaptic transmission in the brain. A major component of the work involves protein expression and crystallization trials. Preference will be give to candidates with strong skills in protein purification and large scale expression in insect cell or mamalian cell culture techniques. Experience in macromolecular crystallography, or cell biology highly desirable. Must have excellent communication skills in English and a superb ability to work as part of a team.
The research facilities at NIH are outstanding with regular access to the SER-CAT beamline at APS. Recent papers describing work from the lab include: Nat Struct Mol Biol 13:1120-7 (Recent papers describing work from the lab include: Nat Struct Mol Biol 13:1120-7 (2006); Nature 440 :456-462 (2006); Neuron 53:829-841 (2007); Neuron 58:720-735 (2008); EMBO J PMID: 18636091 (2008)
Other details: Candidates must have been awarded PhD degree no earlier that 5 years prior to start of fellowship.
NIH is an Affirmative action employer.
J1 visa sponsorship for non US nationals (H1 visa NOT available for this position).
Please submit: CV, names for 3 references, 1 page summary of research experience
Person to contact: Dr. M.L. Mayer
Email address: mayerm@mail.nih.gov
Job Posted: 07/23/08
Job ID Number: 1216858279
Children's National Medical Center
Department: Children's Research Institute
Location: Washington, DC
URL: www.childrensnational.org/research/
Start Date: ASAP
Description: A Post-doctoral position in structural biology is available to train in structural biology of proteins of the urea cycle and arginine biosynthesis. The successful candidate will be mentored in generating and testing scientific hypotheses related to structural biology and biochemistry. He/she will works independently on projects under general guidance. Tasks will include design of study, collection and analysis of data, and reporting of results at symposia and in peer-reviewed manuscripts. Education & Training Required: Ph.D. or equivalent doctoral degree in molecular biology or related field. Major: Must have fulfilled all requirements and obtained the doctoral degree. Majors preferred: Biology, Biochemistry, Structural Biology, Molecular Biology, Cell Biology or Microbiology.
Experience Required: 2-3 years of related experience. Experience may have been obtained during doctoral training. Previous supervisory experience not required.
Special Knowledge, Skills, Abilities: Experience in protein biochemistry and molecular biology methods . Math proficiency and basic statistical skills. Basic UNIX skills. The following specific skills are preferred: construction of plasmids, transfection of cultured cells, gel electrophoresis, PCR analysis, protein purification, RNA and DNA purification, organelle fractionation, SDS/PAGE and western blotting.
Please submit: CV, names and contact information for 3 references
Person to contact: Dr. Dashuang Shi
Surface mail address: 111 Michigan Avenue
Email address: dshi@cnmcresearch.org
Phone number: 202-476-5817
Fax number: 202-476-6014
Job Posted: 07/16/08
Job ID Number: 1216215179
Moffitt Cancer Center
Department: Drug Discovery
Location: Tampa, FL
URL: www.moffitt.org/careers
Start Date: Immediately
Description: Postdoctoral positions are available immediately to study the structure and function of diverse drug targets at the Moffitt Cancer Center. The successful candidates will perform experiments on various medicinally important proteins to discover novel inhibitors with potential as drugs.
Qualified candidates should have a PhD or equivalent degree in Biology, Biochemistry, Chemistry or related field. Experience in protein crystallography or molecular modeling or protein chemistry is required. Additional experience in DNA recombinant technology and over-expression of proteins in bacteria, insect cells and/or yeast is a plus. Excellent verbal and written communication skills are required.
The H. Lee Moffitt Comprehensive Cancer Center is a modern facility on the University of South Florida Campus that conducts research on various aspects of Cancer Biology with emphasis on translational research. It is the third largest Cancer Center in the US based on patient volume. Research environment includes state of the art modern core research facilities.
Please apply online at www.moffitt.org/careers to REQ ID 2622 and send CV, cover letter, and the names and contact information of three references to Dr. Ernst Schönbrunn via email at ernst.schonbrunn@moffitt.org.
Other details: Equal Oportunity/Affirmative Action Employer.
Please submit: CV, cover letter, and contact information for three references
Person to contact: Dr. Ernst Schönbrunn
Email address: ernst.schonbrunn@moffitt.org
Job Posted: 07/11/08
Job ID Number: 1215804677
Brookhaven National Lab
Department: Biology
Location: Long Island, NY
URL: http://www.biology.bnl.gov/structure/fu.html
Start Date: Immediately
Description: A postdoctoral position is available immediately to study a class of metal transporter proteins (see JBC (2004) 279:12043; Science (2007) 317:1746). Potential candidates should have a recent Ph.D. in biochemistry or biophysics with extensive experience in protein crystallography and a strong interest in membrane protein structure biology. We offer competitive salary and outstanding opportunity for career development.
Please submit: CV and names of 3 references
Person to contact: Dax Fu
Email address: dax@bnl.gov
Phone number: 631-344-4208
Fax number: 631-344-3407
Job Posted: 06/27/08
Job ID Number: 1214570161
Johns Hopkins University Medical School
Department: Biophysics and Biophysical Chemistry
Location: Baltimore, Maryland
URL: biophysics.med.jhmi.edu/BIOPHYS/wade.html
Start Date: 7/01/2008
Description: Postdoctoral Position in the Department of Biophysics and Biophysical Chemistry at Johns Hopkins University in the Wade Laboratory. We use a battery of biophysical techniques to study the basis of multidrug recognition and biological switch properties of transcription regulators involved in bacterial multidrug resistance. Techniques used in the lab include steady state and time-resolved fluorescence spectroscopy, x-ray crystallography, analytical ultracentrifugation, isothermal calorimetry as well as a number of gel-based methods. Extensive experience in protein crystallography is preferred; the applicant must also be interested in pursuing techniques, which complement the structural approaches. Competitive salary and benefits.
Please submit: CV, 3 references
Person to contact: Herschel Wade
Surface mail address: 709 Huntarian, 725 N. Wolfe Street
Email address: herschel.wade@jhmi.edu
Phone number: 410 955 3077
Fax number: 410 502 6910
Job Posted: 05/29/08
Job ID Number: 1212087782
EMBL (European Molecular Biology Laboratory)
Location: Hamburg, Germany
URL: www.embl.org/jobs
Start Date: ASAP
Duration: 24 months
Description: We are developing new methods and technologies in macromolecular crystallization and are looking for a postdoc with expertise in the area of x-ray crystallography with an emphasis on the following topics:
-Protein expression and purification
-Macromolecular crystallization
-Protein crystal characterization (e.g. with x-ray or MetriPol analysis)
-Structural biology
The projects involve the testing and design of new crystallization methods and devices and the adaptation of existing techniques to crystallization. Applicants are also encouraged to perform research in structural biology.
Qualifications and experience: In addition to a PhD in a related field, applicants should also have a track record in structural biology. The successful candidate will work in a multidisciplinary environment with collaborators from industry and academia. The EMBL is an international research organization with English as a first language. Good communication and presentation skills are required.
EMBL is an inclusive, equal opportunity employer offering attractive conditions and benefits appropriate to an international research organisation.
Further information on the position can be obtained from Dr. Jochen Mueller Dieckmann: jochenmd@embl-hamburg.de
Please submit: To apply please email a cover letter, CV and names and contact information of three references, quoting ref. no. ACA/08/PD/08 in the subject line, to: application@embl.de
Person to contact: EMBL Personnel Section
Email address: application@embl.de
Job Posted: 05/27/08
Job ID Number: 1211899602
Massachusetts General Hospital/Harvard Medical School
Department: Renal Unit
Location: Boston, MA
Start Date: immediately
Description: A postdoctoral position is immediately available for a highly motivated individual with a recent Ph.D to study structure-function of integrin at Massachusetts General Hospital/Harvard Medical School. Diffractable crystals have been obtained. Experience in protein crystallography is advantageous but not absolutely required if he/she is willing to learn. Preference will be given to candidates who have a strong background in molecular biology and protein expression, especially in mammalian cells.
The initial period of employment is for 2 years starting as soon as possible with renewal for two more years thereafter.
Please submit: CV and names of three references
Person to contact: Dr. Jian-Ping Xiong
Surface mail address: Renal Unit, Massachusetts General Hospital, 149 13th St., Charlestown, MA 02129
Email address: xiong@helix.mgh.harvard.edu
Job Posted: 05/20/08
Job ID Number: 1211301530
Lawrence Berkeley Laboratory
Department: Physical Biosciences
Location: Berkeley, California
URL: cci.lbl.gov/~paul/jobs.html
Start Date: 3/28/2008
Duration: Up to 3 years
Description: This postdoctoral position will study the structure and function of macromolecular complexes and enzymes using X-ray crystallographic methods. This position will be shared between the Center for Protein Folding Machinery (proteinfoldingcenter.org) and the Joint BioEnergy Institute (JBEI). The biological systems to be studied will include: Type-II chaperonins responsible for the refolding of unfolded proteins in archeal and mammalian cells, Glycosyl transferases responsible for the synthesis of hemicellulose in plants, and Novel glycosyl hydrolases that are able to breakdown cellulosic material for biofuels production. The candidate will have experience with using crystallographic methods to study macromolecules; robotic hardware for performing crystallization trials and imaging trays are available. Crystals will be characterized and data collected using the beamline resources of the Berkeley Center for Structural Biology at the Advanced Light Source.
Essential: Primary duties and responsibilities will include using robotic hardware to perform screens for crystallization conditions. Optimization of crystallization conditions. Biophysical characterization of protein samples using standard techniques, such as dynamic light scattering. Characterization of crystals using the Berkeley Center for Structural Biology beamlines at the Advanced Light Source. Collection and analysis of diffraction data, model building and structure refinement. Extensive email and verbal interaction with other researchers. Marginal: Use of small angle X-ray scattering methods to analyze macromolecular complexes in solution.
Essential: Ph.D. or equivalent in a scientific discipline, preferably structural biology, biology, or chemistry. Demonstrated experience of scientific research using crystallographic methods. Experience with crystallization methods. Solid interpersonal skills and the ability to work in a team environment are critical. Ability to communicate with a broad range of researchers. Marginal: Experience with the use of small angle scattering methods. Familiarity with robotic hardware for crystal growth.
NOTE: This is a one year Term appointment with the possibility of renewal under the same terms and conditions, contingent upon continued funding and availability of work.
Lawrence Berkeley National Laboratory is a world leader in science and engineering research, with 11 Nobel Prize recipients over the past 75 years, and 59 present members of the National Academy of Sciences. LBNL conducts unclassified research across a wide range of scientific disciplines and hosts four national user facilities. AA/ EEO employer committed to the development of a safe and diverse workforce. Learn more at http://www.lbl.gov.
For more information about the Center for Protein Folding Machinery visit: http://proteinfoldingcenter.org/ and the Joint BioEnergy Institute visit: http://www.jbei.org/. For more information about the Berkeley Center for Structural Biology visit: http://bcsb.lbl.gov/
To apply: visit http://cjo.lbl.gov/ and search for the job number 21615. Please see http://cjo.lbl.gov/app_instr.html for details of how to apply.
Job Posted: 04/13/08
Job ID Number: 1208144770
University of Illinois at Chicago
Department: BIological Sciences
Location: Chicago, Illinois, USA
Start Date: available immediately
Description: A postdoctoral position is available in the Jeffery lab in the Dept. of Biological Sciences at the University of Illinois at Chicago. The successful candidate will join an ongoing project to determining the structure and mechanism of function of multidrug resistance transmembrane transporters and other transmembrane proteins. Experience in purification, solubilization, crystallization, and X-ray crystal structure determination of membrane proteins is preferred, but candidates with significant experience in protein purification, crystallization, and/or X-ray crystal structure determination of other proteins will also be considered. Also, experience in surface plasmon resonance (SPR) or other methods to study protein-protein interactions or protein-ligand interactions is desired. UIC is the largest university in the Chicago area and is located about 30 min from the Advanced Photon Source, one of the top synchrotrons in the world. Review of applicants will begin immediately. Candidates should please send by email (cjeffery@uic.edu) a current curriculum vitae, names and contact information for three references, and a cover letter describing his or her interest in the project.
Please submit: CV, names and contact information for 3 references, letter describing candidate's interest in the lab and project
Person to contact: Prof. Connie Jeffery
Surface mail address: MC567 900 S. Ashland Ave., Chicago, IL, 60607 USA
Email address: cjeffery@uic.edu
Phone number: 312-996-3168
Fax number: 312-413-2691
Job Posted: 04/02/08
Job ID Number: 1207178630
University of Illinois at Chicago
Department: BIological Sciences
Location: Chicago, Illinois, USA
Start Date: available immediately
Description: A postdoctoral position is available in the Jeffery lab in the Dept. of Biological Sciences at the University of Illinois at Chicago. The successful candidate will join an ongoing project to determining the structure and mechanism of function of multidrug resistance transmembrane transporters and other transmembrane proteins. Experience in purification, solubilization, crystallization, and X-ray crystal structure determination of membrane proteins is preferred, but candidates with significant experience in protein purification, crystallization, and/or X-ray crystal structure determination of other proteins will also be considered. Also, experience in surface plasmon resonance (SPR) or other methods to study protein-protein interactions or protein-ligand interactions is desired. UIC is the largest university in the Chicago area and is located about 30min from the Advanced Photon Source, one of the top synchrotrons in the world. Review of applicants will begin immediately. Candidates should please send by email (cjeffery@uic.edu) a current curriculum vitae, names and contact information for three references, and a cover letter describing his or her interest in the project.
Person to contact: Prof. Connie Jeffery
Surface mail address: MC567 900 S. Ashland Ave., Chicago, IL, 60607 USA
Job Posted: 04/02/08
Job ID Number: 1207177732
Case Western Reserve University
Department: Pharmacology
Location: Cleveland, Ohio
URL: http://pharmacology.case.edu/department/faculty/primary/dealwis.html
Start Date: May 1st
Duration: 2-4 years
Description: A postdoctoral position is available for a highly motivated individual to elucidate structures of cancer targets. Preference will be given to individuals with strong macromolecular crystallography background. Experience in molecular biology is a definite asset.
Person to contact: Chris Dealwis
Surface mail address: 10900 Euclid Ave, Cleveland, Ohio 44106-4965, USA
Email address: cxd114@case.edu
Phone number: (216)368-1652
Job Posted: 03/27/08
Job ID Number: 1206629423
UCSD
Department: Skaggs School of Pharmacy and Pharmaceutical Sciences/Scripps Research Institute
Location: La Jolla/San Diego
Start Date: -
Duration: Indefinite
Description: POSTDOCTORAL RESEARCH POSITION IN STRUCTURAL BIOLOGY OF MAMMALIAN CYTOCHROMES P450
A postdoctoral position is available in spring/summer 2008 for a strongly interactive project between Dr. James R. Halpert at the University of California, San Diego and Drs. C. David Stout and Eric F. Johnson at the Scripps Research Institute. The work is part of an expanding program to develop novel approaches for predicting the metabolism of new therapeutic agents. The specific objective is to elucidate the role of conformational plasticity in ligand recognition by mammalian membrane cytochromes P450 2B [J. Biol. Chem. (2006) 281:5973-5981; J. Biol. Chem. (2006) 281:8051-8061; Biochemistry (2007) 46:11559-11567]. Approaches include X-ray crystallography, isothermal titration calorimetry, fluorescence spectroscopy, site-directed mutagenesis, and molecular modeling. State of the art resources for structural and molecular biology are available at UCSD, Scripps, and SSRL. The successful candidate should have strong formal and practical training in X-ray crystallography including demonstrated expertise in solving, analyzing, and interpreting structures. A Ph.D. in biochemistry, biophysics, molecular biology, chemistry, or a related field is required. Excellent writing skills are highly desirable. Salary is competitive and negotiable. Review of applications will begin immediately and continue until the position is filled. Please provide a current c.v., names and contact information on three references, and a cover letter outlining your research interests.
Please submit: CV, 3 references, cover letter
Person to contact: Loralyn Cross
Surface mail address: 9500 Gilman Drive #0657 San Diego, CA 92093-0657
Email address: lkcross@ucsd.edu
Phone number: 858-822-7819
Fax number: 858-822-5591
Job Posted: 03/24/08
Job ID Number: 1206376979
SGX Pharmaceuticals
Location: San Diego, CA 92121
URL: http://www.sgxpharma.com
Start Date: 4-1-08
Description:
Post Doctoral Position in Crystallization
SGX is a biotechnology company focused on the discovery and development of innovative cancer therapeutics. We have an exciting opportunity for a Post Doctoral researcher to join the Crystallization group working on the Protein Structure Initiative.
The goal of the PSI is to solve structures of proteins with novel folds as well as structures of proteins of community interest. The project continually tests new techniques for efficient production of these structures. The successful candidate will be involved in the optimization of protein crystals, the development of new crystallization techniques, and will be an active participant in the project as a source of ideas and mentorship. The candidate will have access to the expertise of the existing crystallization and project team, several crystallization robots, a comprehensive database for data mining, the SGX-CAT beamline for data collection and the remaining infrastructure of an organization dedicated to solving difficult protein structures. Candidates with an interest in bioinformatics will have an opportunity to participate in construct design and protein engineering. Candidates with experience in protein crystallography will have opportunities to solve and refine novel structures.
Requirements:
A PhD in Crystallography or a related field with extensive crystallization experience. Experience solving structures by SAD or MAD and familiarity with the requisite software a plus. Experience in bioinformatics, molecular biology, or purification a plus.
Expectations:
• Appointee must be eligible for employment in the U.S.
• Appointment duration: Up to 2½ years, funded largely through the NIH Protein Structure Initiative.
• Post Doctoral appointees are eligible for company health benefits.
Person to contact: careers@sgxpharma.com
Job Posted: 02/11/08
Job ID Number: 1202765291
University of Maryland
Department: Center for Advanced Research in Biotechnology
Location: Rockville, Maryland
URL: www.umbi.umd.edu/mariuzza
Start Date: ASAP
Duration: 3-4 years
Description: NIH-funded postdoctoral position available immediately at the Center for Advanced Research in Biotechnology (CARB) of the University of Maryland for a protein crystallographer with recent PhD to join a multidisciplinary team investigating the structural basis for pathogen and tumor cell recognition by the human immune system. Several classes of recognition molecules are under study: antibodies, T cell receptors (TCRs), natural killer (NK) cell receptors, and receptors of the innate immune system (PGRPs, NODs, RIG-I). Projects include X-ray crystallographic studies of: 1) autoimmune and tumor-specific TCRs, 2) NK receptor–MHC complexes, 3) NOD–peptidoglycan complexes, and 4) RIG-I–RNA complexes. Experience in protein biochemistry is highly desirable. [Nature Immunol. 8, 398-408 (2007); Proc. Natl. Acad. Sci. USA 104, 8761-8766 (2007); Immunity 27, 572-584 (2007); Trends Biochem. Sci. 32, 500-508 (2007)]. Visit www.umbi.umd.edu/mariuzza. State-of-the-art X-ray facilities. Excellent opportunities for collaborative studies with molecular biologists and physical biochemists. CARB, a joint research center of the University of Maryland and the National Institute of Standards and Technology, is located in the heart of a major biotech community that includes MedImmune and Human Genome Sciences. Send CV and names of three references to: mariuzza@carb.nist.gov.
Please submit: CV and names of three references
Person to contact: Professor Roy A. Mariuzza
Surface mail address: 9600 Gudelsky Drive, Rockville, MD 20850
Email address: mariuzza@carb.nist.gov
Phone number: 240-314-6243
Fax number: 240-314-6225
Job Posted: 01/29/08
Job ID Number: 1201619066
Lawrence Berkeley National Laboratory
Location: Berkeley, CA
URL: http://jobs.lbl.gov/LBNLCareers/details.asp?jid=21435&p=1
Description: The Molecular Foundry at Berkeley Lab is a user facility for the design, synthesis, and characterization of materials with nanometer dimensions. One of five such Nanoscale Science Research Centers recently established by the U.S. Department of Energy, its charter is to pursue two primary missions: a) conduct outstanding research across the breadth of nanoscience; and b) collaborate with scientists from around the world who visit to use its state-of-the-art instruments, techniques, and expertise to further their own nanoscience research efforts. [See http://foundry.lbl.gov/]
The Inorganic Nanostructures Facility within the Foundry offers a unique postdoctoral position in the field of inorganic nanocrystal materials. This collaboration involves an interdisciplinary team of chemists and materials scientists who explore novel nanocrystals and their integration into functional materials. The research focus is energy and electronic technologies applications. Participation in both nanocrystal synthesis and integration efforts can be anticipated.
Key Responsibilities:
• Synthesis of inorganic nanoparticles in the solution phase and materials characterization of synthesized particles
• Integration of nanoparticles into films and composite materials (i.e., spin coating, dip coating, etc.)
• Microscopic characterization of films and composite materials
• Electrical and/or optical characterization of material properties
Qualifications:
• Relevant materials experience including nanocrystal synthesis, nanowire synthesis, sol-gel chemistry, or similar