X-ray Facility Manager, Rutgers University, Piscataway, NJ [01/02/08]
EMBL (European Molecular Biology Laboratory]
Location: Grenoble France
URL: www.embl.org
Start Date: As soon as possible after closing date
Duration: An initial contract of 3 years will be offered to the successful candidate. This can be renewed, depending on circumstances at the time of review.
Description: A highly motivated scientist is required to join Andrew McCarthy's Synchrotron Crystallography team in the EMBL Grenoble Outstation. This team works in close collaboration with the ESRF on advanced data collection methods and instrumentation with the aim of impacting on challenging structural biological problems. The successful candidate will be responsible for the routine operations, maintenance and user support of the recently built and highly successful microfocus beamline ID23-2 at the ESRF. Other activities, to be carried out together with the EMBL Diffraction Instrumentation team, will include development and commissioning of instruments and scientific software associated with the sample environment on synchrotron MX beamlines, in particular the development of methodologies for collecting X-ray data from microcrystals.
The successful candidate should have a PhD degree and at least two years post-doctoral experience in protein crystallography. An interest in and knowledge of instrumentation and software for macromolecular crystallography beamlines at a synchrotron is highly desirable, and scientific computing skills are required. Successful candidate will work closely with external visitors and should have an excellent command of English. Basic knowledge of French would be advantageous
Please submit: To apply, please email a cover letter, CV (in English) and contact information of three professional references quoting ref. no. ACA/08/054 in the subject line, to: application@embl.de
Job Posted: 07/16/08
Job ID Number: 1216275610
University of Illinois
Department: School of Chemical Sciences/X-ray Facility and Materials Laboratory
Location: Champaign-Urbana, Illinois
URL: www.scs.uiuc.edu/SCS/position/x-ray_post.pdf
Start Date: ASAP after closing date of 06/30/2008
Duration: n/a
Description: The School of Chemical Sciences (SCS) seeks a full-time (12 month) regular academic professional as Research Chemist (crystallographer) to manage the School’s X-ray facility and materials laboratory. The lab provides a complete structural chemistry service with state-of-the-art hardware and software systems that allow for detailed crystallographic analysis of materials from minerals to macromolecules, but especially small molecules. In addition to performing experiments for School faculty, this position is responsible for maintaining the instruments, providing user support and training, supervising facility staff, assisting in preparation of instrument proposals, and overseeing financial reports. The position reports to the School director.
Minimum qualifications: PhD in chemistry, biochemistry, physics, or related field, OR bachelor’s or master’s in same with 5+ years experience; effective interpersonal skills.
Desired qualifications: Prior experience in small molecule crystallography; knowledge of SMART, APEX, and, ideally, GADDS (WAXS), and SAXS; hands-on experience guiding users on these instruments.
Salary: Commensurate with qualifications and experience.
Starting date: As soon as possible after closing date.
Closing date: For full consideration, all application material (including cover letter, curriculum vitae, 3 letters of reference) must be received by 5:00pm on the closing date of June 30, 2008. Applicants may be interviewed before the closing date; however, no hiring decision will be made until after that date.
Application: SCS prefers that applications be submitted through the online application at http://www.scs.uiuc.edu/scs_applicants. Include a cover letter, curriculum vitae, and three references. We strongly recommend that you fill out the online application form as soon as you have assembled the names and email addresses of 3 references. This will create your application file, after which you (and your letter writers) will be able to upload application documents and reference letters. If necessary, applications (including email address) may be mailed to Attn: Research Chemist Search Committee, School of Chemical Sciences, 106 Noyes Lab, 505 S. Mathews Ave., Urbana, IL 61801.
Technical questions: Thomas Rauchfuss (217-333-7355, rauchfuz@uiuc.edu).
Application-related questions: Cheryl Kappes (217-333-5070, scs_apply@scs.uiuc.edu).
Other details: The University of Illinois is an Affirmative Action Equal Opportunity Employer.
Please submit: Submit cover letter, CV, & 3 references online at http://www.scs.uiuc.edu/scs_applicants
Person to contact: Cheryl Kappes
Surface mail address: 505 S. Mathews Ave, Urbana, IL 61801
Email address: scs_apply@scs.uiuc.edu
Phone number: 217-333-5070
Fax number: 217-333-3120
Job Posted: 05/22/08
Job ID Number: 1211481563
University of Kansas
Department: Higuchi Biosciences Center
Location: Lawrence, Kansas
URL: psf.cobre.ku.edu
Start Date: ASAP. Application review begins June 18, 2008
Description: Position Description: The University of Kansas has an immediate career opportunity for a highly motivated and experienced scientist to lead the Protein Structure Laboratory. This Core Laboratory is part of a Center of Biomedical Research Excellence in Protein Structure and Function. It focuses on the use of X-ray crystallography for macromolecular structure determination in support of research groups associated with the COBRE and other research centers and departments. It operates in a highly collegial and collaborative research environment and supports a diverse range of investigators and research projects. The Associate Director will oversee the operation of the laborator; provide expertise, training, and/or service in crystallization, diffraction and structure determination as required by client projects; and assist or collaborate with clients on preparation of manuscripts and grant applications involving macromolecular X-ray crystallography. For further information please see http://psf.cobre.ku.edu. To apply please go to https://jobs.ku.edu, position #00206773.
Position requirements: Ph.D. or equivalent degree in biochemistry or a closely related field with at least two years of experience in application of macromolecular X-ray structure determination. This would preferably include experience working in collaborative and/or team-based projects and least four publications in leading peer-reviewed journals, at least two of which deal with macromolecular X-ray structure determination. Strong oral, written and interpersonal communication skills are also essential for this position.
Salary: Competitive commensurate with experience.
Other details: Complete online application at https://jobs.ku.edeu and attach cover letter, curriculum vitae, and complete contact information for 3 references. Information included in curriculum vitae need not be repeated on application; simply insert "see attached." First consideration given to complete applications received by the review date. EO/AA Employer.
Person to contact: Peggy Williams
Surface mail address: 2099 Constant Ave, Lawrence, KS 66047
Email address: pwilliam@ku.edu
Phone number: 785-864-5340
Fax number: 785-864-3578
Job Posted: 05/09/08
Job ID Number: 1210365592
Job Posted: 05/09/08
Job ID Number: 1210364432
Stanford Linear Accelerator Center, Stanford University
Department: Structural Molecular Biology Group at Stanford Synchrotron Radiation Laboratory
Location: Menlo Park, CA
Duration: 3+ years
Description: Associate Staff Scientist in biological x-ray scattering at Stanford Synchrotron Radiation Laboratory.
The Structural Molecular Biology (SMB) group at the Stanford Synchrotron Radiation Laboratory (SSRL), Stanford University, a national user research facility and a Directorate of the Stanford Linear Accelerator Center, seeks a Ph.D. scientist with a strong experimental background in physicochemical studies of biological macromolecules. The scientist is expected to engage in methodological and technological developments in structural biology using small angle x-ray scattering techniques and collaborative research projects that take advantage of the developments. The scientist is furthermore required to participate in the daily operation and user support of an insertion-device small angle x-ray scattering facility dedicated to structural studies on mostly non-crystalline biological systems. The scientist will be appointed as a Stanford University Academic Staff – Research Associate with working title of Associate Staff Scientist for initially 3 years, and with full employee benefits. The appointment is renewable, subject to performance and grant funding status.
The candidate must have a Ph.D. or equivalent academic degree in biophysics, physical biochemistry, biophysical chemistry, structural biology or a closely related scientific discipline, working on biological macromolecules and/or assemblies. Demonstrated experimental skills in protein or nucleic acid physical chemistry and x-ray scattering/diffraction techniques are required. Considerable experience in instrument development is desirable. Postdoctoral research or comparable training is preferred. The candidate must have demonstrated ability to work in a team environment, and possess excellent communication and interpersonal skills to work effectively with a diverse group of scientists, technical staff as well as external users. She/he should be a highly motivated individual and is expected to play a key role in methodology/instrumentation developments and collaborative research under supervision of a senior scientist. Stanford University is committed to equal opportunity through affirmative action in employment. For additional information on our activities, please visit http://www-ssrl.slac.stanford.edu/~saxs/ or contact Dr. Hiro Tsuruta at tsuruta@slac.stanford.edu. Please send CV and names of three references to Frances Liu, fliu@ssrl.slac.stanford.edu; SSRL, MS69, 2575 Sand Hill Rd, Menlo Park, CA 94025.
Please submit: CV, 3 references
Person to contact: Frances Liu
Surface mail address: 2575 Sand Hill Rd, MS69
Email address: fliu@slac.stanford.edu
Phone number: 650 926 4074
Fax number: 650 926 4100
Job Posted: 04/29/08
Job ID Number: 1209495963
Northwestern University
Department: Chemistry
Location: Evanston, Illinois
URL: www.chem.northwestern.edu/news/item?id=1981
Start Date: 6/1/2008
Description: The Department of Chemistry is rapidly expanding the analytical capabilities in the Integrated Molecular Structure Education and Research Center (IMSERC) that will culminate in the opening of a new 10,000 sq. ft. facility in 2011 and the addition of three new Senior Scientist positions. The facility houses the department’s NMR, mass spectrometry, single crystal X-ray and trace metals analysis capabilities. The IMSERC is an open access analytical research center where users have 24x7 access to capital intensive characterization techniques and expert scientists are available to train users on proper selection of techniques and perform advanced characterization of synthetic materials. The IMSERC currently houses a Smart 1000 and APEX2 X-ray diffractometer. The IMSERC is seeking candidates with a record of teaching, laboratory management and performing structure determination for organic and inorganic compounds. Individual must be familiar with modern software, such as SHELX and JANA, and must have a demonstrated history of solving structures with incorporated solvent, merohedrally twinned crystals and working with air sensitive samples. Competence with refining modulated structures is highly desired. Duties include sample analysis, consultation on crystallization techniques, and assistance with data interpretation, user training and manuscript preparation. In addition, the successful application will assist the Director with the identification of needed additional equipment and the preparation of grant proposals to obtain such equipment. More information about the IMSERC is available at http://www.chem.northwestern.edu/news/item?id=1981. The successful candidate will have a Ph.D. in chemistry or a related field and 5-10 years of X-ray crystallography experience and an extensive publication record. A past history of lab management and/or graduate level teaching experience is strongly preferred. Scientists with industrial backgrounds are encouraged to apply. Salary is commensurate with experience level. Send resume with names and contact information for three references to: Dr. Andrew Ott, Dept. of Chemistry, Northwestern University, 2145 Sheridan Rd., Evanston, IL 60208-3113, a-ott@northwestern.edu. Evaluation will begin on 6/1/2008 and continue until all positions are filled.
Other details: Northwestern University is an equal opportunity, affirmative action educator and employer.
Please submit: CV + 3 references
Person to contact: Andrew Ott
Surface mail address: 2145 N Sheridan Rd
Email address: a-ott@northwestern.edu
Phone number: (847) 467 -1622
Job Posted: 04/24/08
Job ID Number: 1209058050
i-SAFE Inc.
Location: Carlsbad, CA
URL: http://www.isafe.org
Start Date: Immediately
Description: Job Description / Summary: Under the direction of the Director of IT, develops all applications that are necessary for the successful, national and international execution of the i-SAFE Education and Community Outreach Initiative.
Key Responsibilities (work to be accomplished):
• Develops the applications required by the program projects
• Develops an online application to disseminate information to all teams relevant to all aspect of the project
• Develops an online application specifically used by the project implementation teams to post implementation problems and resolutions, to disseminate project execution information.
• Analyzes the requirements for each of these projects and create the requirements analysis documents, the use case scenario documents, the application overview documents
• Designs how the applications will work and how they will integrate with each other and with external systems and technologies; create the detailed application design document
• Defines functional dependencies
• Coordinates the database design, to create the Entity Relationship Diagram (Schema), to define the performance and implementation requirements
• Prototypes the applications and facilitate user review and acceptance sessions
• Integrates the applications with other internal or external systems
• Creates and prepare test data
• Executes testing of all aspects of the applications
• Implements the application into a production environment
• Continually modifies applications to meet changing needs of the Program Director and execution teams
• Continually modifies applications to correct unanticipated bugs.
Requirements / Guidelines:
• Ability to design and code web applications that interact with in-house custom CRM application (Goldmine) in a MS-SQL environment
• Ability to write SQL queries and Stored Procedures
• Develop applications required by the program projects and define functional dependencies
• Monitor website usage, leads, and hits generated through the websites using Microsoft IIS 5/6 tools
• Ability to investigate and analyze information and to draw conclusions.
• Report on and analyze effectiveness of website and optimize website and architecture
• Ability to implement and troubleshoot programming changes and modifications.
• Ability to manage multiple priorities in a fast-paced environment as well as perform and actively participate in a cross-functional team environment
• Must be Self-starter with ability to work independently and proactively.
• Must be extremely detail-oriented and possess excellent verbal and written communication skills.
• Experience working with Goldmine, Flash and Action script a Plus! MCDBA certification is a plus.
Scope / Territory:
This is a headquarters level position (i.e., without geographic dimensions or travel requirements) that has no contemporaries or associates – it is the only position in the corporation responsible for overseeing all Communication Systems and Information Technologies.
Other details: Salary is $52,000 annually with benefits
Please submit: CV, Resume
Person to contact: Roger DeVito
Surface mail address: rdevito@isafe.org
Email address: rdevito@isafe.org
Phone number: 760-603-7911 x11
Job Posted: 03/28/08
Job ID Number: 1206728179
University of Oklahoma
Department: Department of Chemistry and Biochemistry
Location: Norman, Oklahoma
URL: chem.ou.edu
Start Date: Immediate
Description: Macromolecular Crystallography Laboratory Manager. The University of Oklahoma Department of Chemistry and Biochemistry seeks an individual with a doctorate in Chemistry, Biochemistry, or Physics (or a related relevant field) OR a combination of education and experience (e.g. M.S. degree with several years of macromolecular crystallography experience). Experience in both X-ray crystallographic hardware maintenance and computer software support is required. The Manager of the Macromolecular Crystallography Laboratory (MCL) is responsible for: (i) operation and routine maintenance of the departmental X-ray instrumentation used by structural biologists (which includes a Rigaku/MSC RUH3 rotating anode generator, RAXIS IV++ image plate detector system, Osmic confocal optics, and an Oxford Cryosystem Series 700) and (ii) training and supervising users. The successful candidate will have the opportunity to engage in collaborative research in structural biology with users of the X-ray facilities and is also expected to actively participate in structural biology group meetings and spearhead efforts at writing external proposals for instrument upgrades or replacement. The successful candidate should have excellent interpersonal, communication and organizational skills. Experience with all aspects of macromolecular structure determination by X-ray crystallography is highly desirable. The position is available immediately and will remain open until filled. A competitive salary will be offered, commensurate with experience.
Other details: Applicants MUST apply for this position on-line at https://jobs.ou.edu. Computers and personal assistance are available at the Office of Human Resources, 905 Asp Avenue, Room 205, Norman, OK 73019. Refer to the job requisition #4933 on all correspondence. Applicants should submit a cover letter, CV, and at least three letters of reference addressed to: Professor Ann H. West, Department of Chemistry and Biochemistry, University of Oklahoma, Norman, OK 73019. Alternatively, applications in PDF format can be sent to Ms. Sandy Fisher (sgfisher@ou.edu). For further information on this or other OU job opportunities, please call (405) 325-1826, or access our web site at http://hr.ou.edu. The University of Oklahoma is an Affirmative Action/Equal Opportunity employer and encourages diversity in the workplace.
Please submit: Cover letter, CV, and at least three letters of reference
Person to contact: Professor Ann H. West
Surface mail address: Department of Chemistry and Biochemistry, 620 Parrington Oval, University of Oklahoma, Norman, OK 73019
Email address: awest@ou.edu
Phone number: 405-325-1529
Fax number: 405-325-6111
Job Posted: 03/10/08
Job ID Number: 1205171238
Leibniz Institute for Age Research - Fritz Lipmann Institute e.V. (FLI)
Department: Than Laboratory
Location: 07749 Jena, Germany
URL: www.fli-leibniz.de
Start Date: immediately
Duration: 3 to 4 years
Description: The protein crystallography group at the FLI is inviting applications for a
PhD student position (TV-L E13/2)
for the subject
“Crystal structure determination of proteins related to Alzheimer’s disease”.
Our recently established state of the art structural biology lab features well equipped wet lab space for large scale protein expression, purification and supporting biochemical ex-periments, facilities for automated protein crystallization, inhouse X-ray diffraction experiments, access to synchrotron facilities as well as a dedicated linux computer cluster for crystallographic calculations, model building, refinement and structure analysis. The activities of the lab focus on the structural biology of two related biological topics, first the pathological events leading to Alzheimer’s disease (AD) and the physiological functions of AD-related proteins as well as second the structure-function-relationship of proteases with a special focus on processing endoproteases of the secretory pathway.
We are looking for a highly motivated PhD student with genuine interest in structural biology and Alzheimer’s disease. The successful candidate will join a young and still growing team and will participate in both, biochemical/molecular biological and crystallographic work. Previous experience in relevant techniques (cloning, protein expression, purification, crystallization, crystallographic work) is an advantage, but not necessary. The FLI provides an international and dynamic research environment with highly interacting groups. Central activities are organized by the recently inaugurated Leibniz Graduate School on Aging and Age-Related Diseases (LGSA) and are open to all students of the institute.
The position is available immediately and the search will continue until a suitable candidate is found.
More information to the Leibniz Graduate School of Ageing and Age-Related Diseases (LGSA) can be found under http://www.fli-leibniz.de/phd/.
For informal enquiries about the position please contact Dr. Manuel Than +49(0)3641/656306 (http://www.fli-leibniz.de/groups/than_en.php).
The application form may be downloaded from
http://www.fli-leibniz.de/phd/frames/lgsaframesjobs.html.
Please send applications electronically to the LGSA Coordinator ckmueller@fli-leibniz.de citing the code number PhD-86.
05.02.2008
Please submit: for the application procedure please look at: http://www.fli-leibniz.de/phd/
Person to contact: Dr. Claudia Müller
Surface mail address: Beutenbergstraße 1,1 07749 Jena, Germany
Email address: CKMueller@fli-leibniz.de
Phone number: #49(0)3641 656340
Fax number: #49(0)3641 656335
Job Posted: 02/06/08
Job ID Number: 1202284833
Rosalind Franklin University of Medicine and Science
Department: Biochemistry and Molecular Biology
Location: North Chicago, Illinois
URL: www.rosalindfranklin.edu/cms/biochem/
Start Date: ASAP
Duration: Permanent
Description: Rosalind Franklin University of Medicine & Science seeks a ‘hands-on’ macromolecular crystallographer who values being helpful and a ‘hard-money’ academic position.
Job Requirements: A self-starter with good computer and people skills and post-doctoral experience in macromolecular crystallography, and X-ray hardware maintenance. Experience with MAD/SIRAS and MR structure determination, protein purification and crystallization, or extensive computer skills is a plus. Experience with membrane protein purification/crystallization is an additional plus.
Primary Duties/Responsibilities: This is a service position. The X-ray Laboratory Manager must be able to act independently within the framework of the goals and priorities of the Rosalind Franklin Structural Biology Laboratory X-ray Diffraction Facility. Duties include maintaining a user friendly data collection environment:
- Maintaining and operating a Rigaku RU-H X-ray generator, Bruker CCD and Rigaku R-axis IV++ X-ray detectors, Oxford and XSTREAM cryogenic systems, and a TTP LabTech Mosquito crystallization robot.
- Interfacing with vendors and service technicians during periods of instrumentation failure; attending and facilitating data collection during regularly scheduled University supported trips to the APS.
- Maintaining a user friendly operating computing environment.
- Installing and incorporating new computing hardware and peripherals into the computing environment.
- Seeking out projects within the biochemistry department and throughout the university that are amenable to crystallographic analysis.
- Assisting users and potential users in all phases of structure determination and analysis in either a service or teaching capacity, including: protein crystallization, data collection, and structural analysis.
- Acting in an advisory role in the purchase of new crystallographic instrumentation, and new computing hardware and software as opportunities present themselves.
Job training courses and/or attendance in scientific meetings in X-ray methods, X-ray maintenance, computer system administration, or protein crystallization/robotics will be made available to keep the X-ray Laboratory Managers skills up to date.
Other details: Competitive compensation package commensurate with qualifications is provided. Rosalind Franklin University of Medicine & Science is an Equal Opportunity/Affirmative Action Employer.
Please submit: CV and the names of three references
Person to contact: David Harrison
Surface mail address: 3333 Green Bay Rd., North Chicago IL 60064
Email address: David.Harrison@RosalindFranklin.edu
Phone number: 847-578-8609
Fax number: 847-578-3420
Job Posted: 01/24/08
Job ID Number: 1201213589
Rutgers University
Location: Piscataway, NJ
Start Date: January 2008
Duration: full-time
Description: A full-time position is available for an experienced macromolecular crystallographer to support operation and maintenance of a shared X-ray facility and to assist in data collection at home and at synchrotron facilities. The facility is associated with the laboratories of Eddy Arnold, Ann Stock, and Joe Marcotrigiano at the Center for Advanced Biotechnology and Medicine, a joint institute of Rutgers University and UMDNJ-Robert Wood Johnson Medical School in Piscataway, New Jersey. Salary will be commensurate with experience.
Please send a CV, a summary of relevant experience, and contact information for three references to arnold@cabm.rutgers.edu.
Please submit: CV, a summary of relevant experience, and contact information for three references
Person to contact: Eddy Arnold
Email address: arnold@cabm.rutgers.edu
Phone number: 732-235-5323
Fax number: 732-235-5788
Job Posted: 01/02/08
Job ID Number: 1199307447
Last posting: 07/16/08Problems? Send mail to aca@sdsc.edu.