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Protein Data Bank: 60,000 and Counting

As the single worldwide repository for the three-dimensional structures of large molecules and nucleic acids, the Protein Data Bank now contains about 53,000 molecule structures vital to pharmacology, bioinformatics, and education. Based at Rutgers University in New Jersey, and the San Diego Supercomputer Center (SDSC) and Skaggs School of Pharmacy and Pharmaceutical Sciences at the UC San Diego, the freely available online library lets biological researchers and students study, store and share molecular information on a global scale. Shown against a backdrop of just some of the structures archived during the PDB's 37-year history is hemoglobin (PDB ID 4hhb), one of the earliest structures deposited in the PDB. Today, there are dozens of structures of hemoglobin in the PDB, showing the process of oxygen binding and revealing the molecular details of sickle cell anemia.
Image: B. Tolo, SDSC. Source: RCSD PDB.
Source: San Diego Supercomputer Center, UC San Diego

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