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Bob Sinkovits

sinkovit@sdsc.edu
Phone: (858) 822-0995
Personal URL: http://www.sdsc.edu/~sinkovit

Alliance for Cell Signalling Resources

The overall goal of the Alliance for Cellular Signaling (AfCS) is to understand as completely as possible the relationships between sets of inputs and outputs in signaling cells that vary both temporally and spatially. The same goal, stated from a slightly different perspective, is to understand fully how cells interpret signals in a context-dependent manner. The primary responsibility of the AfCS Bioinformatics Laboratory at SDSC is the analysis and dissemination of data generated by the AfCS experimental labs. I will describe the steps that are required to go from raw experimental data to an interactive display that is useful to biologists. I will also touch on some of the secondary data analysis being carried out at SDSC. A second major activity of our laboratory is the development of the Molecule Page database containing information on approximately 3000 proteins that are of importance to signal transduction. I will provide an overview and describe both the automated and author-entered aspects of the Molecule Page project.
   
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