Home > Archives > Additional Archives > J. Andrew McCammon   J. Andrew McCammon, Professor Department of Chemistry and Biochemistry University of California, San Diego La Jolla, California http://chemcca10.ucsd.edu/  Integrated Computational Biology from the Molecule to the Cell Biological activity is a tapestry of physical processes woven together from threads spanning an enormous range of spatial and temporal scales. At the smallest scales, receptor and ligand, enzyme and substrate, ion channel and ion recognize and interact with one another in an intricate dance of Brownian motion, biased by electostatic and other intra- and intermolecular forces. At the cellular level, molecules are arranged in highly organized systems of signal transduction cascades for the purpose of intra- and inter-cellular communication. Computational and structural biology will increasingly be used in the next decade to deepen our understanding of the emergence of biological function at the cellular and higher levels from the molecular level. Some early efforts toward this synthesis will be described, with special reference to neuronal activity. This type of work will set the stage for advances in medicine and other applications.
	Home | SDSC | UCSD | Campus Map | Contact Info
	The San Diego Supercomputer Center (SDSC) is a research unit of the University of California, San Diego, and the leading-edge site of the National Partnership for Advanced Computational Infrastructure. SDSC researchers conduct studies in computational science, develop high-performance computing and networking technologies, and participate in NPACI activities. SDSC -- UC San Diego, MC 0505 -- 9500 Gilman Drive -- La Jolla, CA 92093-0505 -- 858-534-5000 -- 858-534-5152 (fax) info@sdsc.edu © 2001, The Regents of the University of California