Home > Archives > Additional Archives > Phil Bourne   Phil Bourne San Diego Supercomputer Center La Jolla, CA 92093 bourne@sdsc.edu http://www.scripps.edu/pub/olson-web/   Abstract: These are amazing times for biology. With a draft of the human genome complete, attention is turning to the proteome, the complement of proteins encoded by that genome. This focuses attention on the structure of those proteins to better understand function, protein-protein, and protein-ligand interactions. It is here that UCSD has a unique resource, the Protein Data Bank (PDB) from which these studies are possible. The PDB is the single worldwide repository for macromolecular structure data and is operated by the Research Collaboratory for Structural Bioinformatics (RCSB) consisting of Rutgers University, the National Institute of Standards and Technology (NIST), and UCSD. The PDB has recently achieved two milestones. First the 15,000th structure was released - estimates call for 35,000 structures in the next 4-5 years. Second, a paper describing the PDB^Òs capabilities under the direction of the RCSB was the second most cited paper of 2000 according to ScienceWatch®. Our next milestone is to be sure that the PDB is serving not just the global community but the local community in the best way possible. As a first step in this direction, please join us for an informal brown bag lunchtime seminar to learn about existing and new features of the PDB. At this meeting we will define further forums from which we can help you gain the most from this unique resource. All the UCSD PDB staff will be on hand and we look forward to meeting with you.
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