Home > Archives > Additional Archives > Helen M. Berman   Helen M. Berman Director, Protein Data Bank Rutgers University New Jersey berman@rcsb.rutgers.edu http://rutchem.rutgers.edu/faculty/berman.html  The progressive hydration of collagen.Systematic Analyses of Protein Nucleic Acid Interactions Our goal is to understand the structural properties of biological molecules and to relate these structures to their biological functions. Our work on nucleic acids has focused on the effects of base modification of the structure and on the interrelationships of hydration structure, crystal packing, and conformation. Our studies of DNA-protein complexes will help to elucidate the principles that underlie interactions between these macromolecules. Studies on collagen peptides have allowed us to define the structure of the triple helix at atomic resolution and to understand the role of water in mediating intermolecular interactions.
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